Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tin Yu Samuel Law"'
Autor:
Kathleen Hoi Kei Choy, Sze Yan Chan, William Lam, Jing Jin, Tingting Zheng, Tin Yu Samuel Law, Sidney Siubun Yu, Weiping Wang, Linxian Li, Gangcai Xie, Howard Chi Ho Yim, Hao Chen, Ellis Kin Lam Fok
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Spermatogenesis is regulated by a complex network of intercellular communication processes. Extracellular vesicles (EVs) are one of the important mediators in intercellular communication. Previous reports have demonstrated the inv
Externí odkaz:
https://doaj.org/article/c49f4c1b3bd24713bcd24a07ed7c4086
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 1564-1570 (2020)
Cadmium (Cd2+) is considered a human carcinogen as it causes oxidative stress and alters DNA repair responses. However, how Cd2+ is taken up by cells remains unclear. We hypothesized that Cd2+ could be transported into cells via a membrane copper (Cu
Externí odkaz:
https://doaj.org/article/921ae10c67c544e7b1853d2f70404218
Autor:
Sze Yan Chan, Crystal Wing Tung Wan, Tin Yu Samuel Law, David Yiu Leung Chan, Ellis Kin Lam Fok
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15716 (2022)
Apart from the paternal half of the genetic material, the male gamete carries assorted epigenetic marks for optimal fertilization and the developmental trajectory for the early embryo. Recent works showed dynamic changes in small noncoding RNA (sncRN
Externí odkaz:
https://doaj.org/article/8b2e2552d6814038b7fca4bbd2ddc601
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 1564-1570 (2020)
Toxicology Reports, Vol 7, Iss, Pp 1564-1570 (2020)
Graphical abstract
Highlights • CTR1-overexpressing HepG2 and ZFL cell lines were created. • CTR1 overexpression in both HepG2 and ZFL cells increased Cd2+ uptake and toxicity. • CTR1 knockdown in HepG2 cells decreased Cd2+ uptake and toxi
Highlights • CTR1-overexpressing HepG2 and ZFL cell lines were created. • CTR1 overexpression in both HepG2 and ZFL cells increased Cd2+ uptake and toxicity. • CTR1 knockdown in HepG2 cells decreased Cd2+ uptake and toxi
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 66
Copper (Cu) is an essential element regulated by four genes (hCTR1, hATOX1, hATP7A, and hATP7B in humans and zctr1, zatox1, zatp7a, and zatp7b in zebrafish) in copper uptake, distribution, and transport in animal cells. Zebrafish (Danio rerio) shows