Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Tin Oo Khor"'
Autor:
Wenji Li, Ying Huang, Davit Sargsyan, Tin Oo Khor, Yue Guo, Limin Shu, Anne Yuqing Yang, Chengyue Zhang, Ximena Paredes-Gonzalez, Michael Verzi, Ronald P. Hart, Ah-Ng Kong
Publikováno v:
Cell & Bioscience, Vol 8, Iss 1, Pp 1-19 (2018)
Abstract Purpose We investigated the genomic DNA methylation profile of prostate cancer in transgenic adenocarcinoma of the mouse prostate (TRAMP) cancer model and to analyze the crosstalk among targeted genes and the related functional pathways. Met
Externí odkaz:
https://doaj.org/article/36008436c6f24ebeaed303d009626353
Autor:
Siwang Yu, Tin Oo Khor, Ka-Lung Cheung, Wenge Li, Tien-Yuan Wu, Ying Huang, Barbara A Foster, Yuet Wai Kan, Ah-Ng Kong
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8579 (2010)
Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is a transcription factor which regulates the expression of many cytoprotective genes. In the present study, we found that the expression of Nrf2 was suppressed in prostate tumor of the Transgeni
Externí odkaz:
https://doaj.org/article/e955338a3a474214a99b7169fc4565cc
Data from Epigenetic DNA Methylation of Antioxidative Stress Regulator NRF2 in Human Prostate Cancer
Autor:
Ah-Ng Tony Kong, William G. Nelson, Srinivasan Yegnasubramanian, Dominic J. Smiraglia, Yue Liu, Anne Yuqing Yang, Ximena Paredes-Gonzalez, Limin Shu, Francisco Fuentes, Tin Oo Khor
Epigenetic control of NRF2, a master regulator of many critical antioxidative stress defense genes in human prostate cancer (CaP), is unknown. Our previous animal study found decreased Nrf2 expression through promoter CpG methylation/histone modifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3137e457209815a2fa2f3f9cf933596e
https://doi.org/10.1158/1940-6207.c.6544503
https://doi.org/10.1158/1940-6207.c.6544503
Autor:
Ah-Ng Kong, Chung S. Yang, Bandaru S. Reddy, Jefferson Y. Chan, William Ka Lung Cheung, Siwang Yu, Xingpei Hao, Yue Liu, Auemduan Prawan, Mou-Tuan Huang, Tin Oo Khor
The nuclear factor-erythroid 2-related factor 2 (Nrf2) plays a critical role in protecting various tissues against inflammation, which is a potential risk factor for colorectal and other cancers. Our previously published mouse model work showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ca0c17179bbcd355f49a297976851a
https://doi.org/10.1158/1940-6207.c.6543606.v1
https://doi.org/10.1158/1940-6207.c.6543606.v1
Autor:
Ah-Ng Kong, Chung S. Yang, Bandaru S. Reddy, Jefferson Y. Chan, William Ka Lung Cheung, Siwang Yu, Xingpei Hao, Yue Liu, Auemduan Prawan, Mou-Tuan Huang, Tin Oo Khor
Perspective from Increased Susceptibility of Nrf2 Knockout Mice to Colitis-Associated Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb8c0bd48526f38f2b3637df2334dd0
https://doi.org/10.1158/1940-6207.22523130.v1
https://doi.org/10.1158/1940-6207.22523130.v1
Autor:
Ah-Ng Tony Kong, William G. Nelson, Srinivasan Yegnasubramanian, Dominic J. Smiraglia, Yue Liu, Anne Yuqing Yang, Ximena Paredes-Gonzalez, Limin Shu, Francisco Fuentes, Tin Oo Khor
Supplementary figure S2. pGL-1526 or pGL-1169 reporters, either methylated by CpG methyltransferase or not, were co-transfected with pGL 4.75 vector which contains a β-galactosidase gene driven by CMV promoter into PC-3 and HeLa cells, and the lucif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30115338a6d7ca8d1bc8c6cea1b925fa
https://doi.org/10.1158/1940-6207.22524969.v1
https://doi.org/10.1158/1940-6207.22524969.v1
Autor:
Ah-Ng Tony Kong, William G. Nelson, Srinivasan Yegnasubramanian, Dominic J. Smiraglia, Yue Liu, Anne Yuqing Yang, Ximena Paredes-Gonzalez, Limin Shu, Francisco Fuentes, Tin Oo Khor
Supplementary table S1. Supplementary table S1Primers used for MAQMA, BGS, qPCR and ChIP assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034045274eb75b6d45fc810bdcbd8b0a
https://doi.org/10.1158/1940-6207.22524960.v1
https://doi.org/10.1158/1940-6207.22524960.v1
Autor:
Ah-Ng Tony Kong, Harold L. Newmark, Mou-Tuan Huang, Bandaru S. Reddy, Chi-Tang Ho, Sujit Nair, Siwang Yu, Rong Hu, Tin Oo Khor, Guoxiang Shen
Cancer chemopreventive agent sulforaphane (SFN) and dibenzoylmethane (DBM) showed antitumorigenesis effects in several rodent carcinogenesis models. In this study, we investigated the cancer chemopreventive effects and the underlying molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2459d1c4e7e6c255150cf840c1dd267
https://doi.org/10.1158/0008-5472.c.6496811
https://doi.org/10.1158/0008-5472.c.6496811
Autor:
Ah-Ng Tony Kong, Harold L. Newmark, Mou-Tuan Huang, Bandaru S. Reddy, Chi-Tang Ho, Sujit Nair, Siwang Yu, Rong Hu, Tin Oo Khor, Guoxiang Shen
Supplementary Tables 1-2 from Chemoprevention of Familial Adenomatous Polyposis by Natural Dietary Compounds Sulforaphane and Dibenzoylmethane Alone and in Combination in ApcMin/+ Mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a29f1ef433ede19f8f48df9094bb58f
https://doi.org/10.1158/0008-5472.22371467.v1
https://doi.org/10.1158/0008-5472.22371467.v1
Autor:
Akira Inoue, Takashi Shingu, Johnathon L. Rose, Xiaoyan Ma, Christopher A. Bristow, Takahiro Kodama, Alessandro Carugo, Andy M. Zuniga, Angela K. Deem, Giannicola Genovese, Timothy P. Heffernan, Bahar Salimian Rizi, Frederick S. Robinson, Joseph R. Daniele, Ningping Feng, Scott Kopetz, Rosalba Minelli, Mary Sobieski, Kadir C. Akdemir, Jason Roszik, Robert A. Mullinax, Sahil Seth, Michael Peoples, Hideo Tomihara, David G. Menter, Clifford Stephan, Sanjana Srinivasan, Giulio Draetta, Sara Loponte, Yonathan Lissanu Deribe, David Brunell, Virginia Giuliani, Tin Oo Khor, Angela L. Harris, Andrea Viale
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Understanding the mechanisms by which tumors adapt to therapy is critical for developing effective combination therapeutic approaches to improve clinical outcomes for patients with cancer. Methods To identify promising and clinicall