Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Timur V. Schäfer"'
Publikováno v:
Journal of applied toxicology : JATREFERENCES.
The vascular endothelium is not only the semipermeable membrane that separates tissue from blood but also an organ that regulates inflammation, vascular tone, blood clotting, angiogenesis and synthesis of connective tissue proteins. It is susceptible
Publikováno v:
ISRN Toxicology
To estimate the influence of the digestive tract luminal ammonia pool on acute toxic effects of cyclophosphamide, the dynamics of blood ammonia, glutamine and urea level, symptoms of toxic action and the survival time have been studied in rats, intra
Publikováno v:
Toxicology. 224:184-190
Fulminant hyperammonaemia as a threshold effect of coma-inducing dose of sodium thiopental has been revealed in rats. Blood ammonia content increased progressively after the introduction of 1.0 LD50 (but not 0.8 LD50) of sodium thiopental three times
Publikováno v:
Bulletin of Experimental Biology and Medicine. 145:741-743
Blood ammonia concentration increased in the portal vein (by 1.4 times) and inferior vena cava (caudal to the renal vein inflow, by 2.2 times; and cranial to the hepatic vein inflow, by 2.5 times) of rats 3 h after intragastric administration of 16.5
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:692-694
Ammonia inhalation (0.84-1.07 mg/liter, 3 h) was accompanied by a 65% increase in ammonia concentration in mixed blood of intact rats. This treatment did not cause death of intact animals, but potentiated the lethal effect of sodium thiopental and in
Publikováno v:
Drug and chemical toxicology. 34(1)
The kinetics of ammonia of gastrointestinal origin has been studied in rats in hematopoietic or neurovascular forms of acute lethal cyclophosphamide intoxication. Portal and caval blood ammonia, glutamine and urea, and blood markers of cytolysis were
Publikováno v:
Toxicology. 218(1)
Under modeling of thiopental coma influence of sodium succinate and (or) external warming for the support of normal body temperature (isothermal regimen) on the gas exchange, blood gas content, acid–base status and survival rate was studied in rats
Publikováno v:
Toxicology. 202(3)
Rats poisoned with one LD50 of thiopental or amytal are shown to increase oxygen consumption when intraperitoneally given sucinate, malate, citrate, alpha-ketoglutarate, dimethylsuccinate or glutamate (the Krebs cycle intermediates or their precursor