Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Timur Sander"'
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Bacterial viruses, or bacteriophages, are highly abundant in the biosphere and have a major impact on microbial populations. Many examples of phage interactions with their hosts, including establishment of dormant lysogenic and active lytic
Externí odkaz:
https://doaj.org/article/6e05b1b058324b10a609d89d7833c1df
Publikováno v:
ACS Synthetic Biology. 8:1983-1990
Removing transcriptional feedback regulation of metabolic pathways is a classical approach to enhance overproduction of chemicals in microbes. However, disrupting transcriptional regulation can have broad physiological consequences that decrease cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ebcc93e2927087d86606c93e44d550
https://doi.org/10.1021/acssynbio.9b00183
https://doi.org/10.1021/acssynbio.9b00183
The impact of different metabolic environments on cancer cell behavior is poorly understood. Here, we systematically altered nutrient composition of cell culture media and examined the impact on three phenotypes—drug-treatment survival, cell migrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f945fee32a065e5d565e31d3e731aee
https://doi.org/10.1101/2020.06.23.167437
https://doi.org/10.1101/2020.06.23.167437
Publikováno v:
Analytical Chemistry. 89:1624-1631
Cellular metabolite concentrations hold information on the function and regulation of metabolic networks. However, current methods to measure metabolites are either low-throughput or not quantitative. Here we optimized conditions for liquid chromatog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d66ca92de98b9d7f29e8beed2daec3a
https://doi.org/10.1021/acs.analchem.6b03731
https://doi.org/10.1021/acs.analchem.6b03731
Publikováno v:
mBio
mBio, Vol 10, Iss 5, p e01884-19 (2019)
mBio, Vol 10, Iss 5 (2019)
mBio, Vol 10, Iss 5, p e01884-19 (2019)
mBio, Vol 10, Iss 5 (2019)
The dynamics of microbial communities are heavily shaped by bacterium-bacteriophage interactions. But despite the apparent importance of bacteriophages, our understanding of the mechanisms controlling phage dynamics in bacterial populations, and part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cd039f922a2ee8065735b6fdadf810
http://europepmc.org/articles/PMC6737242
http://europepmc.org/articles/PMC6737242
Publikováno v:
Cell Systems
Summary Microbes must ensure robust amino acid metabolism in the face of external and internal perturbations. This robustness is thought to emerge from regulatory interactions in metabolic and genetic networks. Here, we explored the consequences of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c573d12b81bfe1b0d18c4774bf4017
https://pubmed.ncbi.nlm.nih.gov/30638812
https://pubmed.ncbi.nlm.nih.gov/30638812
Publikováno v:
Wiley interdisciplinary reviews. Systems biology and medicine. 10(1)
Cells employ various mechanisms for dynamic control of enzyme expression. An important mechanism is mutual feedback-or crosstalk-between transcription and metabolism. As recently suggested, enzyme levels are often much higher than absolutely needed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3407687576b456f9840e7ef602096452
https://pubmed.ncbi.nlm.nih.gov/28810056
https://pubmed.ncbi.nlm.nih.gov/28810056