Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Timur Samatov"'
Autor:
Anzhalika Sidarovich, Cindy L Will, Maria M Anokhina, Javier Ceballos, Sonja Sievers, Dmitry E Agafonov, Timur Samatov, Penghui Bao, Berthold Kastner, Henning Urlaub, Herbert Waldmann, Reinhard Lührmann
Publikováno v:
eLife, Vol 6 (2017)
Small molecule inhibitors of pre-mRNA splicing are important tools for identifying new spliceosome assembly intermediates, allowing a finer dissection of spliceosome dynamics and function. Here, we identified a small molecule that inhibits human pre-
Externí odkaz:
https://doaj.org/article/db1e5a6f34b4401e948028326c4304a0
Autor:
Andrea Pawallek, Stuart McElroy, Timur Samatov, Lee Mitchell, Andrew Woodland, Ursula Ryder, David Gray, Reinhard Lührmann, Angus I. Lamond
Publikováno v:
The Journal of Biological Chemistry
Background: There is a need for new small molecule pre-mRNA splicing inhibitors as biotools. Results: High throughput screening resulted in the identification of small molecule splicing inhibitors that are active in vitro and in cells. Conclusion: Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3a380045da0527d6a956470aca343f
http://europepmc.org/articles/PMC4263873
http://europepmc.org/articles/PMC4263873