Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Timur R. Samatov"'
Publikováno v:
BioTechniques, Vol 33, Iss 1, Pp 150-156 (2002)
When PCR is carried out in a polyacrylamide gel, each target molecule forms a molecular colony that comprises many copies of the original template. By counting the number of colonies, one can directly determine the target titer, with 100% of the DNA
Externí odkaz:
https://doaj.org/article/722748bc0bb046c9929757787c9d8cdf
Publikováno v:
BioTechniques, Vol 26, Iss 2, Pp 194-198 (1999)
Externí odkaz:
https://doaj.org/article/a4dda1402bab471486f87809328390a4
Autor:
Ann-Kathrin Ernst, Annika Putscher, Timur R Samatov, Anna Suling, Vladimir V Galatenko, Maxim Yu Shkurnikov, Evgeny N Knyazev, Alexander G Tonevitsky, Thomas Haalck, Tobias Lange, Hanna Maar, Jennifer Schröder-Schwarz, Kristoffer Riecken, Udo Schumacher, Daniel Wicklein
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192525 (2018)
Finding additional functional targets for combination therapy could improve the outcome for melanoma patients. In a spontaneous metastasis xenograft model of human melanoma a shRNA mediated knockdown of L1CAM more than sevenfold reduced the number of
Externí odkaz:
https://doaj.org/article/35f4bb6c08f24b1ea2f9c87854f2c513
Autor:
Stepan Nersisyan, Sabrina Arnold, Alexander G. Tonevitsky, Christine Stürken, Susanne Lezius, Udo Schumacher, Timur R. Samatov, D. V. Maltseva, Jan Kortland, Daniel Wicklein, Karin Milde-Langosch
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:1525-1542
PurposeThe transcription factor Fra-2 affects the invasive potential of breast cancer cells by dysregulating adhesion molecules in vitro. Previous results suggested that it upregulates the expression of E- and P-selectin ligands. Such selectin ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09586e4f8cdc28cb9fc76b952300f8c7
https://doi.org/10.1007/s00432-021-03812-2
https://doi.org/10.1007/s00432-021-03812-2
Autor:
Vladimir V. Galatenko, Guido Sauter, Kristoffer Riecken, Hanna Maar, Thorsten Schlomm, Daniel Wicklein, Timur R. Samatov, Tobias Lange, Hartwig Huland, Adam Polonski, Ann Kristin Ahlers, Vera Labitzky, Kristine Kupfernagel, Pascal Steffen, Hartmut Schlüter, Sandra Hanika, Alexander G. Tonevitsky, Ronald Simon, Sarah Starzonek, Tanja Spethmann, Helge von Kriegstein, Udo Schumacher, Steven A. Johnsen
Publikováno v:
European Journal of Cancer. 137:93-107
Background Distant metastasis formation is the major clinical problem in prostate cancer (PCa) and the underlying mechanisms remain poorly understood. Our aim was to identify novel molecules that functionally contribute to human PCa systemic dissemin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62472cbc677e329aedbec4d36d63e894
https://doi.org/10.1016/j.ejca.2020.06.025
https://doi.org/10.1016/j.ejca.2020.06.025
Publikováno v:
Frontiers in Genetics, Vol 4 (2013)
Nuclease resistant extracellular miRNAs have been found in all known biological fluids. The biological function of extracellular miRNAs remains questionable; however, strong evidence suggests that these miRNAs can be more than just byproducts of cell
Externí odkaz:
https://doaj.org/article/ebe1caea3a1c45faad7a934269e376da
Autor:
Udo Schumacher, Dmitry A. Sakharov, Maxim Shkurnikov, Timur R. Samatov, Alexander G. Tonevitsky, N. V. Senyavina, S. A. Tonevitskaya, Vladimir V. Galatenko, Alexey V. Galatenko, Hermann Ehrlich, Uwe Marx
Publikováno v:
BioChip Journal. 11:262-269
Changes in cell adhesion molecule (CAM) expression and miRNAs regulating them are known to be involved in malignant progression in colon cancer. We investigated expression profiles of CAM genes and non-coding RNAs in CaCo2 colon cancer cells in stati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97ffbf886285cbf96bc6484f904bfcc8
https://doi.org/10.1007/s13206-017-1305-x
https://doi.org/10.1007/s13206-017-1305-x
Autor:
Tobias Lange, Daniel Wicklein, Andrey Turchinovich, Alexander G. Tonevitsky, J. A. Makarova, Maxim Shkurnikov, Timur R. Samatov
Publikováno v:
Progress in Histochemistry and Cytochemistry. 51:33-49
MicroRNA (miRNA) is a class of small non-coding RNAs which mediate post-transcriptional gene silencing (PTGS) by sequence-specific inhibition of target mRNAs translation and/or lowering their half-lives in the cytoplasm. Together with their binding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d3f40097f9e19dfa26a01d6c4a33a9
https://doi.org/10.1016/j.proghi.2016.06.001
https://doi.org/10.1016/j.proghi.2016.06.001
Publikováno v:
Progress in Histochemistry and Cytochemistry. 51:25-32
L1CAM is a cell adhesion molecule of the immunoglobulin superfamily which was originally discovered as a major player in the development of the nervous system. L1CAM was demonstrated to have prognostic value in different cancers and to be a promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d604b6a26f0aae720817ba0fb2ec2757
https://doi.org/10.1016/j.proghi.2016.05.001
https://doi.org/10.1016/j.proghi.2016.05.001
Autor:
E. V. Trushkin, Timur R. Samatov, Udo Schumacher, Vladimir V. Galatenko, Dmitriy E. Alexandrov, Galina P. Shibukhova, S. A. Tonevitskaya, Alexander G. Tonevitsky, N. V. Senyavina
Publikováno v:
BioChip Journal. 10:215-220
The human-on-chip technology provides an efficient basis for preclinical studies and has potentially a greater predictive power for human drug response than classical 2D cell culture. Here we report the expression profile of druggable genes in the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fc9557f91c23d1f919825c1dce6032e
https://doi.org/10.1007/s13206-016-0308-3
https://doi.org/10.1007/s13206-016-0308-3