Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Timur O. Yarovinsky"'
Autor:
Nicholas S. Wilcox, Timur O. Yarovinsky, Prakruti Pandya, Vinod S. Ramgolam, Albertomaria Moro, Yinyu Wu, Stefania Nicoli, Karen K. Hirschi, Jeffrey R. Bender
Publikováno v:
iScience, Vol 26, Iss 12, Pp 107985- (2023)
Summary: Tissue resident macrophages are largely of embryonic (fetal liver) origin and long-lived, while bone marrow–derived macrophages (BMDM) are recruited following an acute perturbation, such as hypoxia in the setting of myocardial ischemia. Pr
Externí odkaz:
https://doaj.org/article/9e5e710e290d45e49a4b6036fefe5318
Autor:
Timur O. Yarovinsky, Stephen W. Mason, Manisha Menon, Marie M. Krady, Maria Haslip, Bhaskara R. Madina, Xianyong Ma, Safiehkhatoon Moshkani, Carolina Chiale, Anasuya Chattopadhyay Pal, Bijan Almassian, John K. Rose, Michael D. Robek, Valerian Nakaar
Publikováno v:
iScience, Vol 21, Iss , Pp 391-402 (2019)
Summary: Infections with hepatitis B virus (HBV) can initiate chronic hepatitis and liver injury, causing more than 600,000 deaths each year worldwide. Current treatments for chronic hepatitis B are inadequate and leave an unmet need for immunotherap
Externí odkaz:
https://doaj.org/article/9e64bffbe3444bc090c0083118c49c3a
Autor:
Carolina Chiale, Timur O. Yarovinsky, Stephen W. Mason, Bhaskara R. Madina, Manisha Menon, Marie M. Krady, Safiehkhatoon Moshkani, Anasuya Chattopadhyay Pal, Bijan Almassian, John K. Rose, Michael D. Robek, Valerian Nakaar
Publikováno v:
Vaccines, Vol 8, Iss 2, p 279 (2020)
Virus-like vesicles (VLV) are hybrid vectors based on an evolved Semliki Forest virus (SFV) RNA replicon and the envelope glycoprotein (G) from vesicular stomatitis virus (VSV). Previously, we showed that VLV can be used to express protein antigens a
Externí odkaz:
https://doaj.org/article/efdc067d90fc45c5b1ca5f61f0988c53
Autor:
Timur O. Yarovinsky
Publikováno v:
BioTechniques, Vol 28, Iss 6, Pp 1160-1165 (2000)
Topoisomerase-activated adapters for rapid incorporation of the T7 promoter into PCR products were made by hybridizing synthetic oligonucleotides and activating vaccinia DNA topoisomerase I. The adapters were used to incorporate the T7 promoter seque
Externí odkaz:
https://doaj.org/article/ff1f40cef35e49e6a18f9aaf9490d453
Publikováno v:
Applied Microbiology and Biotechnology
The coronavirus disease (COVID-19) caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. Given that this contagious viral outbreak is still unfolding, it is urgent to understand the pathogenesis of SAR
Publikováno v:
The FASEB Journal. 36
Autor:
Ping Huang, John Hwa, Luoxing Xia, Min Hui Zheng, Kai Weng, Wai Ho Tang, Zhi Zeng, Kathleen A. Martin, Meiling Su, Ying-Ying Liu, Yanfei Wang, Allison C. Ostriker, Timur O. Yarovinsky, Xuejiao Fan, Li Zhang, Yuan Zhang
Publikováno v:
Circ Res
Rationale: Kawasaki disease (KD) is an acute vasculitis of early childhood that can result in permanent coronary artery structural damage. The cause for this arterial vulnerability in up to 15% of patients with KD is unknown. Vascular smooth muscle c
Autor:
Tarun Tyagi, Kanika Jain, Timur O. Yarovinsky, Michael Chiorazzi, Jing Du, Cecilia Castro, Jules Griffin, Asawari Korde, Kathleen A. Martin, Shervin S. Takyar, Richard A. Flavell, Abhijit A. Patel, John Hwa
Publikováno v:
The Journal of experimental medicine. 220(1)
Current understanding of tumor immunosuppressive mechanisms forms the basis for modern day immunotherapies. Immunoregulatory role of platelets in cancer remains largely elusive. Platelets from non-small cell lung cancer (NSCLC) patients revealed a di
Autor:
Hugh S. Taylor, Charlotte W. Usselman, Nina S. Stachenfeld, Jeffrey R. Bender, Timur O. Yarovinsky, Frances E. Steele, Cheryl Leone
Publikováno v:
The Journal of Physiology. 597:2853-2865
KEY POINTS Polycystic ovary syndrome (PCOS) is a complex syndrome with cardiovascular risk factors, including obesity and insulin resistance. PCOS is also associated with high androgens, increases the risk of cardiovascular dysfunction in women. Due
Autor:
Renjing Liu, Luoxing Xia, Sookja K. Chung, Xuejiao Fan, Xiangwen Peng, Yi Xie, Allison C. Ostriker, Kathleen A. Martin, Yuan Zhang, Zhi Zeng, John Hwa, Lei Pi, Timur O. Yarovinsky, Wai Ho Tang, Meiling Su, Xiaoqiong Gu
Publikováno v:
Journal of Clinical Investigation. 129:1372-1386
Upon arterial injury, endothelial denudation leads to platelet activation and delivery of multiple agents (e.g., TXA2, PDGF), promoting VSMC dedifferentiation and proliferation (intimal hyperplasia) during injury repair. The process of resolution of