A rare case of uncharacterized autoinflammatory disease: Patient carrying variations in NLRP3 and TNFRSF1A genes.

Autor: Kilinc OC; Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey., Gayibova K; Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey., Onen MO; Faculty of Science and Letters, Department of Molecular Biology and Genetics, Istanbul Technical University, Istanbul, Turkey., Onat UI; Graduate School of Natural and Applied Sciences, Acibadem University, Istanbul, Turkey.; Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Acibadem University, Istanbul, Turkey., Bülbül A; Graduate School of Health Sciences, Bioinformatics and Biostatistics Department, Acibadem University, Istanbul, Turkey., Timucin AC; Graduate School of Natural and Applied Sciences, Acibadem University, Istanbul, Turkey.; Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Acibadem University, Istanbul, Turkey., Ugurlu S; Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey., Turanli ET; Graduate School of Natural and Applied Sciences, Acibadem University, Istanbul, Turkey.; Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Acibadem University, Istanbul, Turkey.

Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2024 Oct; Vol. 194 (10), pp. e63715. Date of Electronic Publication: 2024 May 20.

Toward Compilation of Balanced Protein Stability Data Sets: Flattening the ΔΔ G Curve through Systematic Enrichment.

Autor: Kebabci N; Department of Biostatistics and Bioinformatics, Institute of Health Sciences, Acibadem University, Istanbul 34752, Turkey., Timucin AC; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem University, Istanbul 34752, Turkey., Timucin E; Department of Biostatistics and Medical Informatics, School of Medicine, Acibadem University, Istanbul 34752, Turkey.

Publikováno v: Journal of chemical information and modeling [J Chem Inf Model] 2022 Mar 14; Vol. 62 (5), pp. 1345-1355. Date of Electronic Publication: 2022 Feb 24.

Structure based peptide design, molecular dynamics and MM-PBSA studies for targeting C terminal dimerization of NFAT5 DNA binding domain.

Autor: Timucin AC; Department of Chemical Engineering, Faculty of Natural Sciences and Engineering, Üsküdar University, Turkey; Neuropsychopharmacology Application and Research Center (NPARC), Üsküdar University, Turkey. Electronic address: ahmetcan.timucin@uskudar.edu.tr.

Publikováno v: Journal of molecular graphics & modelling [J Mol Graph Model] 2021 Mar; Vol. 103, pp. 107804. Date of Electronic Publication: 2020 Nov 13.

Selective targeting of antiapoptotic BCL-2 proteins in cancer.

Autor: Timucin AC; Faculty of Engineering and Natural Sciences, Department of Chemical and Biological Engineering, Uskudar University, Uskudar, Istanbul, Turkey.; Faculty of Engineering and Natural Sciences, Molecular Biology, Genetics and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey., Basaga H; Faculty of Engineering and Natural Sciences, Molecular Biology, Genetics and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey., Kutuk O; Department of Medical Genetics, Adana Medical and Research Center, School of Medicine, Baskent University, Yuregir, Adana, Turkey.

Publikováno v: Medicinal research reviews [Med Res Rev] 2019 Jan; Vol. 39 (1), pp. 146-175. Date of Electronic Publication: 2018 May 30.

AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins.

Autor: Bodur C; Molecular Biology, Genetics, and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey. cagribodur@gmail.com., Karakas B; Molecular Biology, Genetics, and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey., Timucin AC; Molecular Biology, Genetics, and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey., Tezil T; Molecular Biology, Genetics, and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey., Basaga H; Molecular Biology, Genetics, and Bioengineering Program, Sabanci University, Tuzla, Istanbul, Turkey.

Publikováno v: Molecular carcinogenesis [Mol Carcinog] 2016 Nov; Vol. 55 (11), pp. 1584-1597. Date of Electronic Publication: 2015 Sep 16.