Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Timuçin Avşar"'
Autor:
Seher Aydın, Yavuz Ergün, Salma Ghazy, Asuman Çelebi, Turker Kilic, Timuçin Avşar, Serdar Durdağı
Publikováno v:
ACS Omega, Vol 9, Iss 44, Pp 44262-44281 (2024)
Externí odkaz:
https://doaj.org/article/c6f1a1c015fe4736b95a0fe9e3449c86
Autor:
Mark W. Youngblood, Zeynep Erson-Omay, Chang Li, Hinda Najem, Süleyman Coșkun, Evgeniya Tyrtova, Julio D. Montejo, Danielle F. Miyagishima, Tanyeri Barak, Sayoko Nishimura, Akdes Serin Harmancı, Victoria E. Clark, Daniel Duran, Anita Huttner, Timuçin Avşar, Yasar Bayri, Johannes Schramm, Julien Boetto, Matthieu Peyre, Maximilien Riche, Roland Goldbrunner, Nduka Amankulor, Angeliki Louvi, Kaya Bilgüvar, M. Necmettin Pamir, Koray Özduman, Türker Kilic, James R. Knight, Matthias Simon, Craig Horbinski, Michel Kalamarides, Marco Timmer, Amy B. Heimberger, Ketu Mishra-Gorur, Jennifer Moliterno, Katsuhito Yasuno, Murat Günel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Hedgehog signaling mediates embryologic development of the central nervous system and other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular proliferation. Meningiomas, the most common primary brain tumor,
Externí odkaz:
https://doaj.org/article/32c53254d0434114aadc0376769d30b2
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Introduction Peritumoral brain edema (PTBE) has been widely reported with many brain tumors, especially with glioma. Since the blood–brain barrier (BBB) is essential for maintaining minimal permeability, any alteration in the interaction o
Externí odkaz:
https://doaj.org/article/6cd7d3924b3c47ce9068b956e9e68905
Autor:
George Liapakis, Sara Alkhatib, Yavuz Ergun, Berfu Nur Yigit, Gülay Bulut, Melih Acar, Busecan Aksoydan, Ismail Erol, Ramin Ekhteiari Salmas, Bahar Kurt, Vlasios Karageorgos, Turker Kilic, Isik Kantarcioglu, Kutay Cantasir, Serdar Durdagi, Gizem Turan, Timuçin Avşar, Barış Sergi
Publikováno v:
European Journal of Medicinal Chemistry. 145:273-290
AT1 antagonists is the most recent drug class of molecules against hypertension and they mediate their actions through blocking detrimental effects of angiotensin II (A-II) when acts on type I (AT1) A-II receptor. The effects of AT1 antagonists are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08fe56a07c296e06a0ef5b2e96481ab
https://doi.org/10.1016/j.ejmech.2017.12.021
https://doi.org/10.1016/j.ejmech.2017.12.021
Autor:
Fulya Cosan, Ozlem Unay Demirel, Demet Yalcin, Muhammed Mert Sonkaya, Isilsu Ezgi Uluisik, Olida Cecen, Yavuz Furuncuoglu, Deniz Maktav Celikmen, Osman Kara, Erkan Ceylan, Timucin Avsar
Publikováno v:
BMC Rheumatology, Vol 7, Iss 1, Pp 1-17 (2023)
Abstract Background The importance of COVID-19 vaccination for patients on immunosuppressive (IS) medication has increased due to the high risk of severe disease or mortality. Different vaccines have varying efficacy rates against symptomatic COVID-1
Externí odkaz:
https://doaj.org/article/b72f253e97dc444ab02c95e3039493ba
Autor:
Seyma Calis, Berna Dogan, Serdar Durdagi, Asuman Celebi, Ozlem Yapicier, Turker Kilic, Eda Tahir Turanli, Timucin Avsar
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Anti-apoptotic members of the Bcl-2 family proteins play central roles in the regulation of cell death in glioblastoma (GBM), the most malignant type of brain tumor. Despite the advances in GBM treatment, there is still an urgent need for ne
Externí odkaz:
https://doaj.org/article/1572c5b11494469fa14f9d1429dfa998
Autor:
Elif Everest, Ugur Uygunoglu, Melih Tutuncu, Alper Bulbul, Umut Inci Onat, Mehmetcan Unal, Timucin Avsar, Sabahattin Saip, Ugur Bilge, Eda Tahir Turanli, Aksel Siva
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287463 (2023)
BackgroundPredicting the long-term disability outcomes of multiple sclerosis (MS) cases is challenging.ObjectiveWe prospectively analysed our previous MS cohort with initial cerebrospinal fluid (CSF) proteomics data to reveal disability markers after
Externí odkaz:
https://doaj.org/article/afa0c2a5be9545d6a02ccc4aec91fba3
Autor:
Hikmet Turan Suslu, Necati Tatarlı, Davut Ceylan, Hüsnü Süslü, Süheyla Uyar Bozkurt, Timucin Avsar, Bülent Güçlü
Publikováno v:
Neurological Sciences and Neurophysiology, Vol 38, Iss 1, Pp 60-66 (2021)
Objective: Cerebral vasospasm after subarachnoid hemorrhage (SAH) is a major cause of morbidity and mortality. Inflammation is the major molecular mechanism observed in vasospastic SAH. Ozone (O3) has been used as a therapeutic agent in the treatment
Externí odkaz:
https://doaj.org/article/fc319804e48c46b6b0265553a756b306
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Antiapoptotic members of B-cell leukemia/lymphoma-2 (BCL-2) family proteins are one of the overexpressed proteins in cancer cells that are oncogenic targets. As such, targeting of BCL-2 family proteins raises hopes for new therapeutic discoveries. Th
Externí odkaz:
https://doaj.org/article/d6d913ea9c3143c1a13f3237452571d3
Autor:
Timucin Avsar, İlknur Melis Durası, Uğur Uygunoğlu, Melih Tütüncü, Nuri Onat Demirci, Sabahattin Saip, O Uğur Sezerman, Aksel Siva, Eda Tahir Turanlı
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0122045 (2015)
Multiple sclerosis (MS) is an immune-mediated, neuro-inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS) with a heterogeneous clinical presentation and course. There is a remarkable phenotypic heterogeneity i
Externí odkaz:
https://doaj.org/article/06e768ed585c4ccdb304110374274f75