Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Timothy Z. Vitalis"'
Autor:
Chaahat S. B. Singh, Brett A. Eyford, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Mark Okon, Timothy Z. Vitalis, Reinhard Gabathuler, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of diseases of the brain. Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and
Externí odkaz:
https://doaj.org/article/288f8666a28c48d19137c9e3c081e799
Autor:
Brett A. Eyford, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Jacob A. Gordon, Hans Adomat, Emma S.T. Guns, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/7daf6dbc7b4446ec819ea423dd4285c0
Autor:
Brett A. Eyford, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Jacob A. Gordon, Hans Adomat, Emma S.T. Guns, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that transcytoses the BBB, termed MTfp, was chemically conjugated to si
Externí odkaz:
https://doaj.org/article/a03a0a8be37540beb76b28f2d46208c8
Autor:
Delara Karkan, Cheryl Pfeifer, Timothy Z. Vitalis, Gavin Arthur, Maki Ujiie, Qingqi Chen, Sam Tsai, Gerrasimo Koliatis, Reinhard Gabathuler, Wilfred A. Jefferies
Publikováno v:
PLoS ONE, Vol 3, Iss 7 (2008)
Externí odkaz:
https://doaj.org/article/9f67506ae6a349cab9d7a07c614f162f
Autor:
Brett A. Eyford, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Jacob A. Gordon, Hans Adomat, Emma S.T. Guns, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that transcytoses the BBB, termed MTfp, was chemically conjugated to si
Autor:
Chaahat S. B. Singh, Brett A. Eyford, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Mark Okon, Timothy Z. Vitalis, Reinhard Gabathuler, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of diseases of the brain. Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and
Autor:
Chieh-Ju Lu, Hans Adomat, Cheryl G. Pfeifer, Reinhard Gabathuler, Mark Okon, Ian Welch, Kyung Bok Choi, Brett A. Eyford, Jacob A. Gordon, Timothy Z. Vitalis, Rhonda Hildebrandt, Tracy Hill, Mei Mei Tian, Thomas Abraham, Emma S. Tomlinson Guns, Lonna Munro, Chaahat S.B. Singh, Wilfred A. Jefferies
The blood-brain barrier (BBB), hinders the distribution of therapeutics, intended for treatment of diseases of the brain. A twelve-amino acid peptide, termed MTfp, was derived from MTf, and retains the ability to cross the BBB intact and ferry cargo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82474a6d2d9601b56620385b76ec2ede
https://doi.org/10.1101/871186
https://doi.org/10.1101/871186
Autor:
Wilfred A. Jefferies, George Thom, Carl I. Webster, Thomas Abraham, Reinhard Gabathuler, Ian Gurrell, Mei Mei Tian, Timothy Z. Vitalis, Natalia Rodrigo, Jon P. Hatcher, Matthew Burrell
Publikováno v:
J Cereb Blood Flow Metab
Delivery of biologic drugs across the blood–brain barrier is becoming a reality. However, the solutions often involve the assembly of complex multi-specific antibody molecules. Here we utilize a simple 12 amino-acid peptide originating from the mel
Publikováno v:
Cytotechnology. 58:173-179
The expansion of stem cell numbers while retaining their developmental properties is a bioprocess challenge. We compared the growth rates and embryoid body (EB) formation yields of R1 and EFC murine embryonic stem cells (mESC) cultured in two basal m
Autor:
Wilfred A. Jefferies, Robyn P. Seipp, Timothy Z. Vitalis, Alexander R. Moise, Yuanmei Lou, Andrew P. Jeffries, Susan S. Chen, Genc Basha, Bing Cai, Ray S. Gopaul
Publikováno v:
Clinical Cancer Research. 14:1494-1501
Purpose: Tpn is a member of the MHC class I loading complex and functions to bridge the TAP peptide transporter to MHC class I molecules. Metastatic human carcinomas often express low levels of the antigen-processing components Tapasin and TAP and di