Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Timothy Yung"'
Autor:
Molly DiScala, Matthew S Najor, Timothy Yung, Deri Morgan, Abde M Abukhdeir, Melody A Cobleigh
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234146 (2020)
Approximately 20% of breast cancers are HER2-positive. Trastuzumab has improved patient outcomes significantly for these cancers. However, acquired resistance remains a major hurdle in the clinical management of these patients. Therefore, identifying
Externí odkaz:
https://doaj.org/article/53bcf4b5a1294ff8a62f60026c5f7c46
Autor:
Liam Portt, Melody A. Cobleigh, Sanja Turturro, Matthew S. Najor, Satnam Brar, Abde M. Abukhdeir, Timothy Yung
Publikováno v:
Cancer Research. 81:PS18-30
Background: The Ras signaling pathway is a key oncogenic growth signaling pathway. The neurofibromatosis gene (NF1) is a tumor suppressor gene and negative regulator of Ras. Approximately 20% of breast cancers experience loss of active NF1 protein, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16fe5a357eaae6aec9f69ad5087a6a17
https://doi.org/10.1158/1538-7445.sabcs20-ps18-30
https://doi.org/10.1158/1538-7445.sabcs20-ps18-30
Autor:
Sofia Grigoriadou, Asim Khan, Debasish Pyne, Rohit R Ghurye, Timothy Yung, Sorena Kiani-Alikhan
Publikováno v:
Journal of Clinical Immunology. 40:240-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d64829354f9fbfbcabe8fd671aea35f
https://doi.org/10.1007/s10875-019-00722-4
https://doi.org/10.1007/s10875-019-00722-4
Autor:
Liam Portt, Melody A. Cobleigh, Timothy Yung, Matthew S. Najor, Abde M. Abukhdeir, Sanja Turturro, Christopher S. Malarkey
Publikováno v:
Breast Cancer Research and Treatment. 177:325-333
The PI3K pathway, which includes the PI3K catalytic subunits p110α (PIK3CA) and the PI3K regulatory subunit p85α (PIK3R1), is the most frequently altered pathway in cancer. We encountered a breast cancer patient whose tumor contained a somatic alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b2815fcd20ba30ab9171fe0b0380472
https://doi.org/10.1007/s10549-019-05320-x
https://doi.org/10.1007/s10549-019-05320-x
Autor:
Sanja B, Turturro, Matthew S, Najor, Timothy, Yung, Liam, Portt, Christopher S, Malarkey, Abde M, Abukhdeir, Melody A, Cobleigh
Publikováno v:
Breast cancer research and treatment. 177(2)
The PI3K pathway, which includes the PI3K catalytic subunits p110α (PIK3CA) and the PI3K regulatory subunit p85α (PIK3R1), is the most frequently altered pathway in cancer. We encountered a breast cancer patient whose tumor contained a somatic alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93b97457d6a0cccf860c6202250dbc8a
https://pubmed.ncbi.nlm.nih.gov/31209687
https://pubmed.ncbi.nlm.nih.gov/31209687
Autor:
Timothy Yung, Melody A. Cobleigh, Abde M. Abukhdeir, Deri Morgan, Molly DiScala, Matthew S. Najor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0234146 (2020)
PLoS ONE, Vol 15, Iss 6, p e0234146 (2020)
Approximately 20% of breast cancers are HER2-positive. Trastuzumab has improved patient outcomes significantly for these cancers. However, acquired resistance remains a major hurdle in the clinical management of these patients. Therefore, identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1ae28856a4595c9acd4b2541491547
https://doi.org/10.1371/journal.pone.0234146
https://doi.org/10.1371/journal.pone.0234146
Publikováno v:
Journal of Clinical Oncology. 38:e13006-e13006
e13006 Background: Approximately 20% of breast cancers are HER2-positive. Trastuzumab has improved patient outcomes significantly for these cancers. However, acquired resistance occurs in almost all patients with metastatic breast cancer. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a274bf866e93b6668580e3cf40351d95
https://doi.org/10.1200/jco.2020.38.15_suppl.e13006
https://doi.org/10.1200/jco.2020.38.15_suppl.e13006
Autor:
Satnam Brar, Sanja Turturro, Liam Portt, Matthew S. Najor, Timothy Yung, Abde M. Abukhdeir, Melody A. Cobleigh
Publikováno v:
Journal of Clinical Oncology. 36:e24284-e24284
e24284Background: The neurofibromatosis gene (NF1) is a negative regulator of the Ras protein and is lost in ~20% of breast cancers, leading to constitutive activation of Ras. Few studies have expl...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24cc5dc6e4b34a14fb52f6d1a3f7e0da
https://doi.org/10.1200/jco.2018.36.15_suppl.e24284
https://doi.org/10.1200/jco.2018.36.15_suppl.e24284
Publikováno v:
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-LaryngologyCervico-Facial Surgery. 41(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9551066e3631e845733044977cdb5c39
https://pubmed.ncbi.nlm.nih.gov/26293292
https://pubmed.ncbi.nlm.nih.gov/26293292
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.