Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Timothy Wu"'
Autor:
Kelsey Lykins, Robert J. Ossiboff, Ellis Chase, Nina Thompson, Terence M. Farrell, Timothy Wu, Steve A. Johnson, Heather D. S. Walden
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Species of Pterygodermatites are spirurid nematodes that have expanded their geographic distribution worldwide. They infect a variety of mammalian definitive hosts with few reports of potential paratenic infections in amphibian and reptile hosts. In
Externí odkaz:
https://doaj.org/article/97fbf6b1b3cc4452aac1ab11b37beb97
Autor:
Robert Stewart, Shaunik Sharma, Timothy Wu, Sho Okuda, George Xie, Xiao Zhen Zhou, Brian Shilton, Kun Ping Lu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
This review examines the complex role of Pin1 in the development and treatment of cancer. Pin1 is the only peptidyl–prolyl isomerase (PPIase) that can recognize and isomerize phosphorylated Ser/Thr-Pro peptide bonds. Pin1 catalyzes a structural cha
Externí odkaz:
https://doaj.org/article/64cee929871a4400ba07f61aa0b950f8
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Background Praziquantel is the drug of choice for treating the tapeworm Dipylidium caninum in dogs; however, resistance is possible, and regular, non-targeted administration of praziquantel may select for anthelminthic-resistant populations.
Externí odkaz:
https://doaj.org/article/06e83b5ac625437ea31842a372912e00
Autor:
Timothy Wu, Jennifer M Deger, Hui Ye, Caiwei Guo, Justin Dhindsa, Brandon T Pekarek, Rami Al-Ouran, Zhandong Liu, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman
Publikováno v:
eLife, Vol 12 (2023)
Aging is a major risk factor for Alzheimer’s disease (AD), and cell-type vulnerability underlies its characteristic clinical manifestations. We have performed longitudinal, single-cell RNA-sequencing in Drosophila with pan-neuronal expression of hu
Externí odkaz:
https://doaj.org/article/38917c6a7164451fa76d94b52a50b80c
Autor:
Meigen Yu, Hui Ye, Ruth B De-Paula, Carl Grant Mangleburg, Timothy Wu, Tom V Lee, Yarong Li, Duc Duong, Bridget Phillips, Carlos Cruchaga, Genevera I Allen, Nicholas T Seyfried, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010760 (2023)
Heterozygous variants in the glucocerebrosidase (GBA) gene are common and potent risk factors for Parkinson's disease (PD). GBA also causes the autosomal recessive lysosomal storage disorder (LSD), Gaucher disease, and emerging evidence from human ge
Externí odkaz:
https://doaj.org/article/2fca0b159dad43719f3d2b2f9cfef08b
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d79529441e724a4ca74ebe838c9152f8
Autor:
Carl Grant Mangleburg, Timothy Wu, Hari K. Yalamanchili, Caiwei Guo, Yi-Chen Hsieh, Duc M. Duong, Eric B. Dammer, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-17 (2020)
Abstract Background Tau neurofibrillary tangle pathology characterizes Alzheimer’s disease and other neurodegenerative tauopathies. Brain gene expression profiles can reveal mechanisms; however, few studies have systematically examined both the tra
Externí odkaz:
https://doaj.org/article/110a287c3f324a6eb0a20036440b10b1
Publikováno v:
Pathogens, Vol 12, Iss 2, p 204 (2023)
Taenia crassiceps is a parasite of wild canids and dogs that serve as definite hosts, harboring the adult cestode, whereas rodents are the intermediate hosts in which the metacestode/cysticercus/larval stage occurs. Fecal-oral transmission ensures th
Externí odkaz:
https://doaj.org/article/d967ca6a9414404fa3c3a4c43b8262fd
Autor:
Loes M. Olde Loohuis, Serghei Mangul, Anil P. S. Ori, Guillaume Jospin, David Koslicki, Harry Taegyun Yang, Timothy Wu, Marco P. Boks, Catherine Lomen-Hoerth, Martina Wiedau-Pazos, Rita M. Cantor, Willem M. de Vos, René S. Kahn, Eleazar Eskin, Roel A. Ophoff
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract The role of the human microbiome in health and disease is increasingly appreciated. We studied the composition of microbial communities present in blood across 192 individuals, including healthy controls and patients with three disorders aff
Externí odkaz:
https://doaj.org/article/17562bdf44234e028412afcbfe62fa09
Autor:
Timothy Wu, Caiwei Guo, Jennifer Marie Deger, Justin Dhindsa, Rami Al‐Ouran, Joshua M Shulman
Publikováno v:
Alzheimer's & Dementia. 18