Výsledky vyhledávání - "Timothy W. Noblitt"

Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT

Autor: Kelly A Davis, Timothy W. Noblitt, Victor J. Wroblewski, John E. Hale, Gerald W. Becker, Christy Michelle Newton, Derrick R. Witcher, Radmila Micanovic, Ho Yeong Song, John M. Richardson, Shenshen Dou

Publikováno v: Biochemical Pharmacology. 65:657-667

Fas ligand (FasL) and Fas receptor are members of the tumor necrosis factor (TNF) receptor and ligand family that play an important role in regulating apoptosis in normal physiology. Decoy receptor 3 (DcR3) is a novel member of the TNF receptor super

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72614f79284d3cbfbbf6cd41f7cfdc83
https://doi.org/10.1016/s0006-2952(02)01612-x

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Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20

Autor: Scott W. Rowlinson, Timothy W. Noblitt, Victor J. Wroblewski, Scott Cooper, Peter K. Lambooy, Hal E. Broxmeyer, Jonathan Wendell Tetreault, Derrick Ryan Witcher, Kellie A. Brune, Niles Fox, Giao Hangoc, Josef G. Heuer, Danise Paige Rogers, Ling Liu, Chunjin Ding, Wei Zeng, James R. Miller, Ganesh R. Sharma

Publikováno v: Blood. 102(9)

In a search for novel growth factors, we discovered that human interleukin-20 (IL-20) enhanced colony formation by CD34+ multipotential progenitors. IL-20 had no effect on erythroid, granulocyte-macrophage, or megakaryocyte progenitors. IL-20 transge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e444aed6494777f127ea9e986a50e385
https://pubmed.ncbi.nlm.nih.gov/12855566

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High-efficiency gene transfer into normal and adenosine deaminase-deficient T lymphocytes is mediated by transduction on recombinant fibronectin fragments

Autor: Karen E. Pollok, David R. Williams, Helmut Hanenberg, Ikunoshin Kato, David J. Emanuel, Wendy L. Schroeder, Timothy W. Noblitt

Publikováno v: Journal of virology. 72(6)

Primary human T lymphocytes are powerful targets for genetic modification, although the use of these targets in human gene therapy protocols has been hampered by low levels of transduction. We have shown previously that significant increases in the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf48b4f6cab60ec11f28d7f9654419b
https://pubmed.ncbi.nlm.nih.gov/9573255

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