Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Timothy W. McCardle"'
Autor:
Ricardo J. Gonzalez, Geoffrey T. Gibney, Leslie M. Turner, Ragini R. Kudchadkar, Keiran S.M. Smalley, Timothy W. McCardle, Jacob J. Benedict, Sarah Sloot, Vernon K. Sondak, Jonathan S. Zager, Jeffrey S. Weber, Jane L. Messina, R. C. DeConti
Publikováno v:
Melanoma Research, 26(1), 83-87. LIPPINCOTT WILLIAMS & WILKINS
Selective BRAF inhibitors (BRAFi) yield objective responses in 50% of patients with metastatic BRAF V600E mutant melanoma. Adding an MEK inhibitor increases this response rate to 70%. Limited data are available on the outcomes of unresectable stage I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16d38f31c0846b2de9e11dd6e633516
https://research.rug.nl/en/publications/e7053d76-4bbe-428d-9d29-4187e5918d44
https://research.rug.nl/en/publications/e7053d76-4bbe-428d-9d29-4187e5918d44
Publikováno v:
Molecular Pathology and Diagnostics of Cancer ISBN: 9789400771918
Advances and discoveries in molecular genetics over the past decade have literally changed the face of diagnosis and treatment decisions for patients with melanoma and non-melanoma skin cancer. These include genetic analysis of skin biopsies as a dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51c82f47ba9269da5aa2e66dac4012d2
https://doi.org/10.1007/978-94-007-7192-5_16
https://doi.org/10.1007/978-94-007-7192-5_16
Autor:
Narges K. Tafreshi, Josef Vagner, Mark C. Lloyd, Keiran S.M. Smalley, Ariosto S. Silva, Steven A. Enkemann, Vernon K. Sondak, Yolaine Jeune-Smith, Timothy W. McCardle, Veronica Estrella, Tingan Chen, David L. Morse
The melanocortin 1 receptor (MC1R) is overexpressed in most melanoma metastases, making it a promising target for imaging of melanomas. In this study, the expression of MC1R in a large fraction of patients with melanoma was confirmed using mRNA and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b053d03a2c4fcb1b457dc274fd3ec4c3
https://europepmc.org/articles/PMC3785103/
https://europepmc.org/articles/PMC3785103/
Publikováno v:
Current problems in cancer. 34(1)
Publikováno v:
Seminars in oncology. 36(6)
Autor:
Josef Vagner, Tingan Chen, David L. Morse, Veronica Estrella, Natalie M. Barkey, Timothy W. McCardle, Narges K. Tafreshi, Robert J. Gillies, Steven A. Enkemann
Publikováno v:
Cancer Research. 72:4557-4557
Melanoma is curable by means of surgical excision if diagnosed in early stages, but once the metastatic stage is reached, prognosis is poor because the tumor is resistant to most cures. Therefore, a melanoma targeted probe that can deliver therapy to