Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Timothy W. Felton"'
Publikováno v:
npj Antimicrobials and Resistance, Vol 2, Iss 1, Pp 1-6 (2024)
Abstract Nitrofurantoin has shown exceptional durability against resistance over 70 years of use. This longevity stems from factors such as rapid achievement of therapeutic concentrations, multiple physiological targets against bacteria, low risk of
Externí odkaz:
https://doaj.org/article/77006aca0fa841e6a3bb50fe2fa4c7f0
Autor:
Mohammad H. Alshaer, PharmD, PhD, Roy Williams, MPH, Mays J. Mousa, PharmD, MBA, Kaitlin M. Alexander, PharmD, Kelly L. Maguigan, PharmD, Kayihura Manigaba, PharmD, Nicole Maranchick, PharmD, Bethany R. Shoulders, PharmD, Timothy W. Felton, MBBS, PhD, Sumith K. Mathew, MD, Charles A. Peloquin, PharmD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 11, p e0993 (2023)
IMPORTANCE:. Sepsis and septic shock are major healthcare problems that need early and appropriate management. OBJECTIVES:. To evaluate the association of daily cefepime pharmacokinetic/pharmacodynamic (PK/PD) parameters with change in Sequential Org
Externí odkaz:
https://doaj.org/article/5bf159a8cfa740ee8799b467d4b4c8cf
Autor:
Nicole F. Maranchick, Jessica Webber, Mohammad H. Alshaer, Timothy W. Felton, Charles A. Peloquin
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1696 (2023)
Background: The objective was to identify associations between beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) targets and Gram-negative bacteria resistance emergence in patients. Methods: Retrospective data were collected between 2016 to 2019 at
Externí odkaz:
https://doaj.org/article/f04399bc18b84c49959109bff8c455cb
Autor:
Peter S. Cunningham, Gareth B. Kitchen, Callum Jackson, Stavros Papachristos, Thomas Springthorpe, David van Dellen, Julie Gibbs, Timothy W. Felton, Anthony J. Wilson, Jonathan Bannard-Smith, Martin K. Rutter, Thomas House, Paul Dark, Titus Augustine, Ozgur E. Akman, Andrew L. Hazel, John F. Blaikley
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Background Assessing circadian rhythmicity from infrequently sampled data is challenging; however, these types of data are often encountered when measuring circadian transcripts in hospitalized patients.Methods We present ClinCirc. This method combin
Externí odkaz:
https://doaj.org/article/db8cfa4c021e4b49aecacbf1e0167777
Autor:
Tjeerd Pieter van Staa, Victoria Palin, Yan Li, William Welfare, Timothy W. Felton, Paul Dark, Darren M. Ashcroft
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Previous research reported that individuals prescribed antibiotics frequently develop antimicrobial resistance. The objective of this study was to evaluate whether frequent antibiotic use is associated with reduced hospital admiss
Externí odkaz:
https://doaj.org/article/cb799d763acd4ee4864b92da2f041f79
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Type 1 myotonic dystrophy (DM1) causes sleep disordered breathing and respiratory failure due to a combination of obstructive sleep apnoea, reduced central drive and respiratory muscle weakness. Noninvasive ventilation (NIV) is commonly used for trea
Externí odkaz:
https://doaj.org/article/57d8f625ad34486195973159a3ff325e
Autor:
Mohammad H. Alshaer, Nicole Maranchick, Chen Bai, Kelly L. Maguigan, Bethany Shoulders, Timothy W. Felton, Sumith K. Mathew, Mamoun T. Mardini, Charles A. Peloquin
Publikováno v:
Antimicrob Agents Chemother
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are the most common intensive care unit (ICU) infections. We aimed to evaluate the association of early and cumulative beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197d4d4b1fdf1b60c020f135b7bb8a71
https://doi.org/10.1128/aac.00563-22
https://doi.org/10.1128/aac.00563-22