Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Timothy W. Church"'
Autor:
Georgiana F. Stan, Timothy W. Church, Ellie Randall, Jenna R. M. Harvey, Jon T. Brown, Kevin A. Wilkinson, Jonathan G. Hanley, Neil V. Marrion
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Accumulation of tau is observed in dementia, with human tau displaying 6 isoforms grouped by whether they display either 3 or 4 C-terminal repeat domains (3R or 4R) and exhibit no (0N), one (1N) or two (2N) N terminal repeats. Overexpression
Externí odkaz:
https://doaj.org/article/479dc19da1834338ad8d3270d0699c51
Autor:
Matthew G. Gold, João Antunes, Trevor G. Smart, Parul Tewatia, Olivia Eriksson, Saad Hannan, Jeanette Hellgren Kotaleski, Timothy W Church
Publikováno v:
eLife, Vol 10 (2021)
eLife, Vol. 10
eLife
eLife, Vol. 10
eLife
Interplay between the second messengers cAMP and Ca2+ is a hallmark of dynamic cellular processes. A common motif is the opposition of the Ca2+-sensitive phosphatase calcineurin and the major cAMP receptor, protein kinase A (PKA). Calcineurin dephosp
Autor:
Trevor G. Smart, Saad Hannan, Jeanette Hellgren Kotaleski, Parul Tewatia, Matthew G. Gold, Olivia Eriksson, João Antunes, Timothy W Church
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a61fe525ed30adbe747333e58f7adc2
https://doi.org/10.7554/elife.68164.sa2
https://doi.org/10.7554/elife.68164.sa2
Autor:
Matthew G. Gold, Timothy W Church
Publikováno v:
Patch Clamp Electrophysiology ISBN: 9781071608173
Cultured hippocampal slices from rodents, in which the architecture and functional properties of the hippocampal network are largely preserved, have proved to be a powerful substrate for studying healthy and pathological neuronal mechanisms. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::912c869bf03ad48eccc7d995fbf18f28
https://doi.org/10.1007/978-1-0716-0818-0_12
https://doi.org/10.1007/978-1-0716-0818-0_12
Autor:
Timothy W, Church, Matthew G, Gold
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2188
Cultured hippocampal slices from rodents, in which the architecture and functional properties of the hippocampal network are largely preserved, have proved to be a powerful substrate for studying healthy and pathological neuronal mechanisms. Here, we
Publikováno v:
Church, T W, Brown, J & Marrion, N 2019, ' β3-Adrenergic receptor-dependent modulation of the medium afterhyperpolarization in rat hippocampal CA1 pyramidal neurons ', Journal of Neurophysiology, vol. 121, no. 3, pp. 773-784 . https://doi.org/10.1152/jn.00334.2018
Action potential firing in hippocampal pyramidal neurons is regulated by generation of an afterhyperpolarization (AHP). Three phases of AHP are recognized, with the fast AHP regulating action potential firing at the onset of a burst and the medium an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697586329ff1ac1389d82c88cb6b6489
https://research-information.bris.ac.uk/en/publications/b32515a6-e7ca-40f1-a130-ef73ecfe9a3e
https://research-information.bris.ac.uk/en/publications/b32515a6-e7ca-40f1-a130-ef73ecfe9a3e
Publikováno v:
Journal of neurophysiology. 121(3)
Action potential firing in hippocampal pyramidal neurons is regulated by generation of an afterhyperpolarization (AHP). Three phases of AHP are recognized, with the fast AHP regulating action potential firing at the onset of a burst and the medium an
Autor:
Nathaniel Moulson, Bradley J. Petek, Michael J. Ackerman, Timothy W. Churchill, Sharlene M. Day, Jonathan H. Kim, Stephanie A. Kliethermes, Rachel Lampert, Benjamin D. Levine, Matthew W. Martinez, Manesh R. Patel, Dermot Phelan, Kimberly G. Harmon, Aaron L. Baggish, Jonathan A. Drezner
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 11 (2023)
Background Clinical practice recommendations for participation in sports and exercise among young competitive athletes with cardiovascular conditions at risk for sudden death are based largely on expert consensus with a paucity of prospective outcome
Externí odkaz:
https://doaj.org/article/dd29d276c5bf452f8ae88ebd7aea44fd
Autor:
Nathaniel Moulson, Bradley J. Petek, Timothy W. Churchill, Jonathan A. Drezner, Kimberly G. Harmon, Stephanie A. Kliethermes, Pranav Mellacheruvu, Manesh R. Patel, Aaron L. Baggish
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 16 (2022)
Background Initial protocols for return to play cardiac testing in young competitive athletes following SARS‐CoV‐2 infection recommended cardiac troponin (cTn) to screen for cardiac involvement. This study aimed to define the diagnostic yield of
Externí odkaz:
https://doaj.org/article/5f074a8996844fc0946d7d6504805dfb
Autor:
Nathaniel Moulson, Bradley J. Petek, Aaron L. Baggish, Kimberly G. Harmon, Stephanie A. Kliethermes, Manesh R. Patel, Timothy W. Churchill, Jonathan A. Drezner
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 2, p 72 (2023)
The Outcomes Registry for Cardiac Conditions in Athletes (ORCCA) study is a large-scale prospective investigation evaluating the cardiovascular effects and outcomes of SARS-CoV-2 infection on young competitive athletes. This review provides an overvi
Externí odkaz:
https://doaj.org/article/f76b8be9da46413b80ab6527c6bcc7c0