Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Timothy W Lefever"'
Autor:
Timothy W Lefever, Julie A Marusich, Brian F Thomas, Daniel G Barrus, Nicholas C Peiper, Richard C Kevin, Jenny L Wiley
Publikováno v:
Substance Abuse: Research and Treatment, Vol 11 (2017)
Smoking is the most common route of administration for cannabis; however, vaping cannabis extracts and synthetic cannabinoids (“fake marijuana”) in electronic cigarette devices has become increasingly popular. Yet, most animal models used to inve
Externí odkaz:
https://doaj.org/article/a65c2fc707214d2d8cf8704090b35c12
Autor:
M Hunter Land, Siva A. Vanapalli, Marton L. Toth, Marcel O. Bonn-Miller, Laura MacNair, Timothy W Lefever, Erica N. Peters
Publikováno v:
Cannabis and Cannabinoid Research. 6:522-527
Introduction: Despite widespread use of cannabidiol (CBD), no lifelong toxicity study has been published to date. Caenorhabditis elegans is often used in preclinical lifelong toxicity studies, due ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e53d5933a60568d25107c0e1ca04f58
https://doi.org/10.1089/can.2020.0103
https://doi.org/10.1089/can.2020.0103
Autor:
Rayetta G. Henderson, Timothy W. Lefever, Melissa M. Heintz, Kristen R. Trexler, Susan J. Borghoff, Marcel O. Bonn-Miller
Publikováno v:
Food and Chemical Toxicology. 176:113778
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0afc1aa6239d18e078ba461c4fd185b
https://doi.org/10.1016/j.fct.2023.113778
https://doi.org/10.1016/j.fct.2023.113778
Autor:
Rayetta G. Henderson, Brian T. Welsh, John M. Rogers, Susan J. Borghoff, Kristen R. Trexler, Marcel O. Bonn-Miller, Timothy W. Lefever
Publikováno v:
Food and Chemical Toxicology. 176:113786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44658cd7694861a170d44b240720043e
https://doi.org/10.1016/j.fct.2023.113786
https://doi.org/10.1016/j.fct.2023.113786
Publikováno v:
NeuroToxicology. 73:161-167
A recent push to provide more translationally relevant preclinical models for examination of pharmacological mechanisms underlying inhaled substances of abuse has resulted in the development of equipment and methods that allows exposure of freely mov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c82405defb6dd7103a3d70f7d1118a
https://doi.org/10.1016/j.neuro.2019.04.002
https://doi.org/10.1016/j.neuro.2019.04.002
Autor:
Susan Sumner, Maria Moreno Caffaro, Shyam Aravamudhan, Scott L. Watson, Purvi R. Patel, Timothy R. Fennell, Ninell P. Mortensen, Timothy W. Lefever, Rodney W. Snyder, Stephanie A. Montgomery
Publikováno v:
J Appl Toxicol
Little is known about the uptake, biodistribution, and biological responses of nanoparticles (NPs) and their toxicity in developing animals. Here, male and female juvenile Sprague-Dawley rats received four consecutive daily doses of 10 mg/kg Al2 O3 N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5047a8922424d7bd27102132da7621d8
https://europepmc.org/articles/PMC8169715/
https://europepmc.org/articles/PMC8169715/
Autor:
Jenny L, Wiley, Daniel G, Barrus, Charlotte E, Farquhar, Timothy W, Lefever, Thomas F, Gamage
Publikováno v:
Prog Neuropsychopharmacol Biol Psychiatry
Cannabis edibles are becoming more common in an increasingly diverse population of users, and the impact of first pass metabolism on cannabis’s pharmacological profile across age and sex is not well understood. The present study examined the impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc38ab91aa13a99a7d068b1cc84b4739
https://pubmed.ncbi.nlm.nih.gov/32810571
https://pubmed.ncbi.nlm.nih.gov/32810571
Publikováno v:
Neuropharmacology. 137:133-140
Edible cannabis-infused products are an increasingly popular method of using cannabis in the United States. Yet, preclinical research to determine mechanisms underlying abuse of Δ9-tetrahydrocannabinol (THC), the primary psychoactive constituent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e332c398b8234e8d4a32622f72cf8e2d
https://doi.org/10.1016/j.neuropharm.2018.04.018
https://doi.org/10.1016/j.neuropharm.2018.04.018
Autor:
Timothy W. Lefever, Richard C. Kevin, Brian F. Thomas, Iain S. McGregor, Alexander L. Kovach, Jenny L. Wiley, Thomas F. Gamage
Publikováno v:
Forensic Toxicology. 37:17-26
The use of novel synthetic cannabinoids as intoxicants continues in spite of associated health risks. These compounds are typically smoked or vaporized, but many synthetic cannabinoids contain thermally labile chemical moieties. This study investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac2a3f9994f9809b3fbf9b8d8dd789d
https://doi.org/10.1007/s11419-018-0430-0
https://doi.org/10.1007/s11419-018-0430-0
Publikováno v:
Neuropharmacology. 134:73-81
Diversion of synthetic cannabinoids from the lab to drugs of abuse has become increasingly prevalent in recent years. Moreover, as earlier synthetic cannabinoids were banned, manufacturers introduced a new supply of novel compounds to serve as replac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbe06468ed0984db20308bac2018596
https://doi.org/10.1016/j.neuropharm.2017.10.041
https://doi.org/10.1016/j.neuropharm.2017.10.041