Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Timothy V. Hartke"'
Autor:
Amanda Klein, Hans Jürgen Solinski, Nathalie M Malewicz, Hada Fong-ha Ieong, Elizabeth I Sypek, Steven G Shimada, Timothy V Hartke, Matthew Wooten, Gang Wu, Xinzhong Dong, Mark A Hoon, Robert H LaMotte, Matthias Ringkamp
Publikováno v:
eLife, Vol 10 (2021)
In humans, intradermal administration of β-alanine (ALA) and bovine adrenal medulla peptide 8–22 (BAM8-22) evokes the sensation of itch. Currently, it is unknown which human dorsal root ganglion (DRG) neurons express the receptors of these prurito
Externí odkaz:
https://doaj.org/article/e6aba7ebcd4b4ee18d4d4f7f6c1487b1
Publikováno v:
Pain.
Transient voltage-gated sodium currents are essential for the initiation and conduction of action potentials in neurons and cardiomyocytes. The amplitude and duration of sodium currents are tuned by intracellular fibroblast growth factor homologous f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20850ff4bba8d6b9655063cd33c94e65
https://pubmed.ncbi.nlm.nih.gov/36607284
https://pubmed.ncbi.nlm.nih.gov/36607284
Autor:
Nathalie M. Malewicz, Gang Wu, Hans Jürgen Solinski, Matthew Wooten, Hada Fong-ha Ieong, Elizabeth I. Sypek, Timothy V. Hartke, Amanda H. Klein, Mark A. Hoon, Steven G. Shimada, Matthias Ringkamp, Xinzhong Dong, Robert H. LaMotte
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
In human, intradermal administration of β-alanine (ALA) and bovine adrenal medulla peptide 8-22 (BAM8-22) evokes the sensation of itch. Currently, it is unknown which human dorsal root ganglion (DRG) neurons express the receptors of these pruritogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b1c8729811750e65ca02b9443ac89c
https://elifesciences.org/articles/64506
https://elifesciences.org/articles/64506
Autor:
Matthias Ringkamp, Michael Tal, Timothy V Hartke, Matthew Wooten, Alvin McKelvy, Brian P Turnquist, Yun Guan, Richard A Meyer, Srinivasa N Raja
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42105 (2012)
Loperamide reverses signs of mechanical hypersensitivity in an animal model of neuropathic pain suggesting that peripheral opioid receptors may be suitable targets for the treatment of neuropathic pain. Since little is known about loperamide effects
Externí odkaz:
https://doaj.org/article/f92b488c86624eb2b2eb6e658d0acba4
Autor:
Matthias Ringkamp, Lisa M Johanek, Jasenka Borzan, Timothy V Hartke, Gang Wu, Esther M Pogatzki-Zahn, James N Campbell, Beom Shim, Raf J Schepers, Richard A Meyer
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9076 (2010)
Different classes of unmyelinated nerve fibers appear to exhibit distinct conductive properties. We sought a criterion based on conduction properties for distinguishing sympathetic efferents and unmyelinated, primary afferents in peripheral nerves.In
Externí odkaz:
https://doaj.org/article/e0f197db62ab4bbaa186c9674624ef5a
Autor:
Amanda H. Klein, Roberto De Col, Martin Schmelz, Alina Vyshnevska, Richard W. Carr, Frank Bosmans, Timothy V. Hartke, Peter W. Reeh, Brian Turnquist, Matthias Ringkamp, Joseph L. Mankowski
Publikováno v:
The Journal of Neuroscience. 37:5204-5214
Voltage-gated sodium (NaV) channels are responsible for the initiation and conduction of action potentials within primary afferents. The nine NaVchannel isoforms recognized in mammals are often functionally divided into tetrodotoxin (TTX)-sensitive (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c15181b93a62a40541b28f9703583a7
https://doi.org/10.1523/jneurosci.3799-16.2017
https://doi.org/10.1523/jneurosci.3799-16.2017
Autor:
Xinzhong Dong, Matthias Ringkamp, Alene F. Carteret, Alvin D. McKelvy, Chih-yang Chung, Yun Guan, Fei Yang, Srinivasa N. Raja, Timothy V. Hartke
Publikováno v:
European Journal of Pain. 16:1021-1032
Background The analgesic properties and mechanisms of loperamide hydrochloride, a peripherally acting opioid receptor agonist, in neuropathic pain warrant further investigation. Methods We examined the effects of systemic or local administration of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2196deb9939c75036f9e39d5c2f24c48
https://doi.org/10.1002/j.1532-2149.2012.00148.x
https://doi.org/10.1002/j.1532-2149.2012.00148.x
Autor:
Lisa M. Johanek, Richard A. Meyer, Matthias Ringkamp, Yun Guan, Beom Shim, Yuan Xiang Tao, Timothy V. Hartke, Srinivasa N. Raja
Publikováno v:
Pain. 138:318-329
Studies in experimental models and controlled patient trials indicate that opioids are effective in managing neuropathic pain. However, side effects secondary to their central nervous system actions present barriers to their clinical use. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5a70f2df4f92e9c283266d01a5d443
https://doi.org/10.1016/j.pain.2008.01.004
https://doi.org/10.1016/j.pain.2008.01.004
Autor:
Richard A. Meyer, George L. Lambrinos, Timothy V. Hartke, John W. Griffin, Matthias Ringkamp, Beom Shim
Publikováno v:
Pain. 128:40-51
Growing evidence suggests that uninjured afferents may play an important role in neuropathic pain following nerve injury. The excitability of nociceptive neurons in the L4 spinal nerve appears to be enhanced following an injury to the adjacent L5 spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425793d7701bde52f7abe6e0633be3ff
https://doi.org/10.1016/j.pain.2006.08.023
https://doi.org/10.1016/j.pain.2006.08.023
Autor:
Timothy V. Hartke, Michael Lim, Michael Guarnieri, Matthew Wooten, Benjamin S. Carson, Matthias Ringkamp
Publikováno v:
Journal of neurosurgery. 124(2)
OBJECT Percutaneous treatments for trigeminal neuralgia are safe, simple, and effective for achieving good pain control. Procedural risks could be minimized by using noninvasive imaging techniques to improve the placement of the radiofrequency thermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22ba22654134e061691ca53fdfd27c5
https://pubmed.ncbi.nlm.nih.gov/26274997
https://pubmed.ncbi.nlm.nih.gov/26274997