Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Timothy V, Murphy"'
Autor:
Shaun L. Sandow, Irit Markus, Dana S. Hutchinson, Fiona C. Britton, Samantha L. Saunders, Timothy V. Murphy, Lu Liu
Publikováno v:
British Journal of Pharmacology. 178:1789-1804
BACKGROUND AND PURPOSE The physiological role of vascular β3 -adrenoceptors is not fully understood. Recent evidence suggests cardiac β3 -adrenoceptors are functionally effective after down-regulation of β1 /β2 -adrenoceptors. The functional inte
Autor:
Nathan M. Luque, Sandra M. Lowe, Leo L. Leader, Steven D. Horrowitz, Timothy V. Murphy, Shaun L. Sandow
Publikováno v:
The FASEB Journal. 36
Autor:
Timothy V. Murphy, Michael A. Perry, Lesley G. Ulman, Nicole A. Marden, Balu Daniel, Ghada Hanna, Gary D. Housley
Publikováno v:
The FASEB Journal. 36
Autor:
Lu Liu, Kim-Chi Phan-Thien, Li Zhang, D. Shevy Perera, Irit Markus, Timothy V. Murphy, Stelina Drimousis
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:28-39
The tachykinin NK2 receptor plays a key role in gastrointestinal motor function. Enteric neurons release neurokinin A (NKA) which activates NK2 receptors on gastrointestinal smooth muscle, leading to contraction and increased motility. In patients wi
Autor:
Shaun L. Sandow, Timothy V. Murphy
Publikováno v:
Current Opinion in Pharmacology. 45:8-15
Localized, oscillating Ca2+ signals have been identified in discrete microdomains of vascular endothelial cells. At myoendothelial contacts (between endothelial and smooth muscle cells), both endothelial Ca2+ pulsars (IP3-mediated release of intracel
Autor:
Samantha L, Saunders, Dana S, Hutchinson, Fiona C, Britton, Lu, Liu, Irit, Markus, Shaun L, Sandow, Timothy V, Murphy
Publikováno v:
British journal of pharmacologyREFERENCES. 178(8)
The physiological role of vascular βStudies were performed in cremaster muscle arteries isolated from male Sprague-Dawley rats. β-adrenoceptor expression was assessed through RT-PCR and immunofluorescence. Functional effects of βAll three β-adren
Autor:
Nadim eNaser, Andrzej S. Januszewski, Bronwyn E. Brown, Alicia J. Jenkins, Michael A Hill, Timothy V Murphy
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
Post-translational modification of proteins in diabetes, including formation of advanced glycation end products (AGEs) are believed to contribute to vascular dysfunction and disease. Impaired function of the endothelium is an early indicator of vascu
Externí odkaz:
https://doaj.org/article/bbc2556667f14b38af2f9c9b527c4f4f
Publikováno v:
Pharmacology & Therapeutics. 174:79-96
Transient receptor potential canonical type 3 channels (TRPC3) are expressed in neural, cardiac, respiratory and vascular tissues, with both similarities and differences between human and animal models for the same cell types. In common with all memb
Autor:
Timothy V, Murphy, Shaun L, Sandow
Publikováno v:
Current opinion in pharmacology. 45
Localized, oscillating Ca
Autor:
Fiona C. Britton, Sianne Toemoe, Sevvandi Senadheera, Timothy V. Murphy, Shaun L. Sandow, T. Hilton Grayson, Arjna Kanagarajah, Leo R. Leader, Paul P. Bertrand
Publikováno v:
Vascular Pharmacology. 83:66-77
This study investigated the expression and function of transient receptor potential vanilloid type-3 ion channels (TRPV3) in uterine radial arteries isolated from non-pregnant and twenty-day pregnant rats. Immunohistochemistry (IHC) suggested TRPV3 i