Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Timothy V, Beischlag"'
Autor:
Gary H. Perdew, Preeti Ramadoss, Brett C. DiNatale, Timothy V. Beischlag, Brett D. Hollingshead
The pleiotropic cytokine interleukin 6 (IL-6) is involved in immune cell homeostasis. Additionally, IL-6 expression and signaling in tumor cells have been shown to elicit both protumor and antitumor properties. There is a plethora of mechanistic know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::612597ff456f8a455abf44923ebe5359
https://doi.org/10.1158/0008-5472.c.6497535
https://doi.org/10.1158/0008-5472.c.6497535
Autor:
Gary H. Perdew, Preeti Ramadoss, Brett C. DiNatale, Timothy V. Beischlag, Brett D. Hollingshead
Supplementary Figure 1 from Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cea3f21b1080bfc587be6b607e71df6
https://doi.org/10.1158/0008-5472.22374657
https://doi.org/10.1158/0008-5472.22374657
Publikováno v:
Synapse (New York, N.Y.)REFERENCES. 76(3-4)
The retromer complex is an evolutionarily conserved protein complex involved in the endosomal recycling of various cargo proteins. It is ubiquitously expressed in all tissue and is found in both invertebrate as well as mammalian nervous systems, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83aafc01b5bc04df8ddee2d96d6b912
https://pubmed.ncbi.nlm.nih.gov/35080780
https://pubmed.ncbi.nlm.nih.gov/35080780
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0126548 (2015)
Acute lymphoid leukemia is a common type of blood cancer and chemotherapy is the initial treatment of choice. Quantifying the effect of a chemotherapeutic drug at the cellular level plays an important role in the process of the treatment. In this stu
Externí odkaz:
https://doaj.org/article/31ad56db129c4c72b7eba1c901717686
Autor:
Shabnam Massah, Robert Hollebakken, Mark P Labrecque, Addie M Kolybaba, Timothy V Beischlag, Gratien G Prefontaine
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97535 (2014)
Regulatory elements for the mouse growth hormone (GH) gene are located distally in a putative locus control region (LCR) in addition to key elements in the promoter proximal region. The role of promoter DNA methylation for GH gene regulation is not w
Externí odkaz:
https://doaj.org/article/4b5386e07cc14aa6bf5b1615ae59c524
Autor:
Mark P Labrecque, Mandeep K Takhar, Julienne M Jagdeo, Kevin J Tam, Christina Chiu, Te-Yu Wang, Gratien G Prefontaine, Michael E Cox, Timothy V Beischlag
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99214 (2014)
Localized hypoxia in solid tumors activates transcriptional programs that promote the metastatic transformation of cells. Like hypoxia-inducible hyper-vascularization, loss of the retinoblastoma protein (Rb) is a trait common to advanced stages of tu
Externí odkaz:
https://doaj.org/article/e276625e12064928ae0b5aed567d1aed
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Genetics
BMC Genetics
Background DNA methylation is an epigenetic modification that mainly repress expression of genes essential during embryogenesis and development. There are key ATPase-dependent enzymes that read or write DNA methylation to remodel chromatin and regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec810266bda20aa34961f56bf97613f2
https://doi.org/10.1186/s12863-020-0809-x
https://doi.org/10.1186/s12863-020-0809-x
Autor:
Mark P Labrecque, Mandeep K Takhar, Brett D Hollingshead, Gratien G Prefontaine, Gary H Perdew, Timothy V Beischlag
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29545 (2012)
The activated AHR/ARNT complex (AHRC) regulates the expression of target genes upon exposure to environmental contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Importantly, evidence has shown that TCDD represses estrogen receptor (ER)
Externí odkaz:
https://doaj.org/article/15c17945b68e44948544a812e0705ebb
Autor:
Paul C. H. Li, Robert T. M. Payer, Hamide Sharifi, Karan Parekh, Timothy V. Beischlag, Avid Khamenehfar
Utilizing the microfluidic single-cell technique enables us to study the inhibition of multidrug resistance due to drug efflux on a single triple-negative breast cancer cell. This method examines drug efflux inhibition on a single cell in a microflui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3012b2cbcd1272e6762db48d4ac6b9d6
https://doi.org/10.1016/bs.mie.2019.07.010
https://doi.org/10.1016/bs.mie.2019.07.010
Autor:
John E. Elliott, Tony D. Williams, Timothy V. Beischlag, Lilian I. L. Wong, Heidi A. Currier, Michael E. Cox, Alexandra R. Reers
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 30:239-242
The effects of the organic flame retardant 1,2-Dibromo-4-(1,2-dibromoethyl) cyclohexane (TBECH) on androgen receptor target gene expression were examined in the human LNCaP prostate cancer cell line. While γ-/δ-TBECH alone led to a significant incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bf9d500f8a538c37b4553d1bbcebedf
https://doi.org/10.1002/jbt.21784
https://doi.org/10.1002/jbt.21784