Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Timothy Soos"'
Autor:
Tong Zi, Sriram Sathyanaryanan, Su Chul Jang, Kyriakos Economides, Dalia Burzyn, Charan Leng, Kelvin Zhang, Samuel Kasera, Sushrut Kamerkar, Olga Burenkova, Timothy Soos
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7a62daf685a84d058424068cd97f0118
Autor:
Sushrut Kamerkar, Charan Leng, Kelvin Zhang, Olga Burenkova, Su Chul Jang, Tong Zi, Sílvia Sisó, Kyriakos Economides, Karl Schmidt, Timothy Soos, Dalia Burzyn, Sriram Sathyanaryanan
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Sushrut Kamerkar, Charan Leng, Olga Burenkova, Su Chul Jang, Kelvin Zhang, Samuel Kasera, Tong Zi, Sanah Langer, Silvia Siso, Timothy Soos, Dalia Burzyn, Sriram Sathyanaryanan
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Timothy Soos, Su Chul Jang, Samuel Kasera, Kelvin Zhang, Dalia Burzyn, Kyriakos D. Economides, Tong Zi, Charan Leng, Sushrut Kamerkar, Sriram Sathyanaryanan, Olga Burenkova
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTumor associated macrophages (TAMs) play a critical role in tumor immunosuppression and resistance to immune checkpoint blockade. Reprogramming ‘M2’ TAMs to a proinflammatory ‘M1’ phenotype by selectively silencing M2 phenotype-driv
Autor:
Sushrut Kamerkar, Charan Leng, Olga Burenkova, SuChul Jang, Kelvin Zhang, Yanyan Liu, William Dahlberg, Kyriakos Economides, Timothy Soos, Dalia Burzyn, Sriram Sathyanarayanan
Publikováno v:
Cancer Research. 82:3508-3508
Background: Tumor-associated macrophages (TAMs) and myeloid derived suppressor cells (MDSCs) promote an immunosuppressive milieu by inhibiting T-cell activation and recruitment, leading to resistance to immune checkpoint therapies. Interleukin 10 (IL
Autor:
Christine McCoy, Sriram Sathyanarayanan, Olivier Duchamp, Charan Leng, Timothy Soos, Olga Burenkova, Hugo Quillery, Sylvie Maubant, Su Chul Jang, Marie Leblanc, Kelvin Zhang, Dalia Burzyn, William K. Dahlberg, Kyriakos D. Economides, Sushrut Kamerkar
Publikováno v:
Cancer Research. 81:1792-1792
Background: Tumor-associated macrophages (TAMs) promote tumor progression and resistance to immune checkpoint inhibitors and are thus attractive targets for cancer immunotherapy. The STAT6 transcriptional network is an important driver of the immune-
Autor:
Dalia Burzyn, William K. Dahlberg, Eric Zhang, Sylvie Maubant, Sriram Sathyanarayanan, Kyriakos D. Economides, Scott Estes, Olivier Duchamp, Tong Zi, Katherin Kirwin, Charan Leng, Timothy Soos, Raymond S. H. Yang, Sushrut Kamerkar, Olga Burenkova, Su Chul Jang
Publikováno v:
Cancer Research. 80:5696-5696
Background: Tumor-associated macrophages (TAMs) are potent drivers of an immunosuppressive tumor microenvironment by reducing T cell recruitment and activation, promoting resistance to immune checkpoint inhibition. Experimental therapies blocking mon
Autor:
Katherine Kirwin, Eric Zhang, Kyriakos D. Economides, Sriram Sathyanarayanan, Scott Estes, Suhrut Kamerkar, Adam T. Boutin, Raymond Yang, Charan Leng, William K. Dahlberg, Tong Zi, Dalia Burzyn, Timothy Soos, Su Chul Jang, Kelvin Zhang, Olga Burenkova
Publikováno v:
Cancer Immunology Research. 8:A50-A50
Tumor-associated macrophages (TAMs) are potent drivers of an immunosuppressive tumor microenvironment and may be an attractive therapeutic target. Experimental therapies tested thus far block myeloid cell differentiation, leading to ineffective antig
Autor:
Vincent Ollion, Ivan Perrot, Frédéric Montanana-Sanchis, Rabie Chelbi, Juliette Savoret, Thien-Phong Vu Manh, Bjarne Bogen, Nicholas Colletti, Christophe Caux, Even Fossum, Michael Shaw, Marc Dalod, Timothy Soos, Cindy Sanchez, Christian Chabannon, Anne-Claire Doffin, Sreekumar Balan, Hong Liu, Didier Bechlian, Jenny Valladeau-Guilemond, Carine Asselin-Paturel
Publikováno v:
The Journal of Immunology
Human monocyte-derived dendritic cell (MoDC) have been used in the clinic with moderately encouraging results. Mouse XCR1+ DC excel at cross-presentation, can be targeted in vivo to induce protective immunity, and share characteristics with XCR1+ hum