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pro vyhledávání: '"Timothy S. Mulvihill"'
Canonical BAF (CBAF) is an essential 12-protein chromatin-remodeling complex that slides and/or ejects nucleosomes using the alternative catalytic ATP-dependent DNA translocases BRG1 or BRM. Currently, the regulation of BRG1/BRM activity and nucleoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::515db8ac45247616f301d9b7d8b5eff3
https://doi.org/10.1101/2021.10.26.465931
https://doi.org/10.1101/2021.10.26.465931
Autor:
Jared J. Barrott, Lena Wagner, Bradley R. Cairns, Timothy S. Mulvihill, Mary L. Nelson, Ting Liu, Jinxiu Li, Sydney Lynn Lambert, Amir Pozner, Ian C. Lock, Li Li, Ana Banito, Kevin B. Jones, Michael B. Ward, Allie H. Grossmann, Benjamin B. Ozenberger
Publikováno v:
Cancer discovery. 11(10)
Reduced protein levels of SMARCB1 (also known as BAF47, INI1, SNF5) have long been observed in synovial sarcoma. Here, we show that combined Smarcb1 genetic loss with SS18–SSX expression in mice synergized to produce aggressive tumors with histomor
Autor:
Delphi Chatterjee, Marc D. Porter, Jennifer H. Granger, Alexis C. Crawford, Ryan Robinson, Timothy S. Mulvihill, John S. Spencer, Lars B. Laurentius, Kimberly E. Hanson
Publikováno v:
The Analyst. 142:177-185
Patient care and prevention of disease outbreaks rely heavily on the performance of diagnostic tests. These tests are typically carried out in serum, urine, and other complex sample matrices, but are often plagued by a number of matrix effects such a
Autor:
Marc D. Porter, Jennifer H. Granger, Timothy S. Mulvihill, John S. Spencer, Delphi Chatterjee, Lars B. Laurentius, Alexis C. Crawford, Kimberly E. Hanson
Publikováno v:
The Analyst. 142:186-196
The ability to detect tuberculosis (TB) continues to be a global health care priority. This paper describes the development and preliminary assessment of the clinical accuracy of a heterogeneous immunoassay that integrates a serum pretreatment proces
Autor:
Timothy S. Mulvihill, Venkataswamy Sorna, Emily R. Theisen, Savita Sankar, Laura M. Hoffman, Sunil Sharma, Mary C. Beckerle, Stephen L. Lessnick, Jared Bearss
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 20(17)
Purpose: Ewing sarcoma is a pediatric bone tumor that absolutely relies on the transcriptional activity of the EWS/ETS family of fusion oncoproteins. While the most common fusion, EWS/FLI, utilizes lysine-specific demethylase 1 (LSD1) to repress crit
Autor:
Timothy S. Mulvihill, Emily R. Theisen, Savita Sankar, Sunil Sharma, Venkataswamy Sorna, Stephen L. Lessnick, Jared Bearss
Publikováno v:
Cancer Research. 74:3679-3679
Ewing sarcoma is an aggressive pediatric bone tumor characterized by an absolute reliance on the transcriptional activity of the EWS/ETS family of transcription factor fusion oncoproteins. The most common fusion is EWS/FLI, present in 85-95% of cases