Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Timothy S. Mulligan"'
Autor:
Arife Unal Eroglu, Timothy S. Mulligan, Liyun Zhang, David T. White, Sumitra Sengupta, Cathy Nie, Noela Y. Lu, Jiang Qian, Lisha Xu, Wuhong Pei, Shawn M. Burgess, Meera T. Saxena, Jeff S. Mumm
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential. Similarly, among nearly 300 genetic
Externí odkaz:
https://doaj.org/article/26f4e85cc8724161b9abfd475abe72c6
Autor:
Michelle H Rich, Abigail V Sharrock, Timothy S Mulligan, Frazer Matthews, Alistair S Brown, Hannah R Lee-Harwood, Elsie M Williams, Janine N Copp, Rory F Little, Jenni JB Francis, Claire N Horvat, Luke J Stevenson, Jeremy G Owen, Meera T Saxena, Jeff S Mumm, David F Ackerley
Publikováno v:
bioRxiv
SummaryFunctional screening of environmental DNA (eDNA) libraries is a potentially powerful approach to discover enzymatic “unknown unknowns”, but is usually heavily biased toward the tiny subset of genes preferentially transcribed and translated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a912240b02a0284245439c0f64bc50dc
https://doi.org/10.1101/2023.03.24.534183
https://doi.org/10.1101/2023.03.24.534183
Autor:
Jennifer L Anderson, Timothy S Mulligan, Meng-Chieh Shen, Hui Wang, Catherine M Scahill, Frederick J Tan, Shao J Du, Elisabeth M Busch-Nentwich, Steven A Farber
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007105 (2017)
As model organism-based research shifts from forward to reverse genetics approaches, largely due to the ease of genome editing technology, a low frequency of abnormal phenotypes is being observed in lines with mutations predicted to lead to deleterio
Externí odkaz:
https://doaj.org/article/113fcbe6ef3a4950b7f16a238692a5a8
Autor:
Abigail V. Sharrock, Timothy S. Mulligan, Kelsi R. Hall, Elsie M. Williams, David T. White, Liyun Zhang, Kevin Emmerich, Frazer Matthews, Saumya Nimmagadda, Selena Washington, Katherine D. Le, Danielle Meir-Levi, Olivia L. Cox, Meera T. Saxena, Anne L. Calof, Martha E. Lopez-Burks, Arthur D. Lander, Ding Ding, Hongkai Ji, David F. Ackerley, Jeff S. Mumm
Publikováno v:
Nature methods, vol 19, iss 2
Transgenic expression of bacterial nitroreductase (NTR) enzymes sensitizes eukaryotic cells to prodrugs such as metronidazole (MTZ), enabling selective cell-ablation paradigms that have expanded studies of cell function and regeneration in vertebrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fc22cea9ed01529cf478d87a37f105
https://escholarship.org/uc/item/1fn995n4
https://escholarship.org/uc/item/1fn995n4
Autor:
Brant M. Weinstein, Qin Tang, Nora Torres Yordán, Anthony Anselmo, Daniel Castranova, Riadh Lobbardi, Ruslan I. Sadreyev, Jason N. Berman, Timothy S. Mulligan, John C. Moore, Van N. Pham, Robert S. Liwski, David M. Langenau
Publikováno v:
Molecular and Cellular Biology. 36:2868-2876
ZAP70 [zeta-chain (TCR)-associated protein kinase, 70-kDa], is required for T cell activation. ZAP70 deficiencies in humans and null mutations in mice lead to severe combined immune deficiency. Here, we describe a zap70 loss-of-function mutation in z
Autor:
Brant M. Weinstein, Eric T. Sause, Timothy S. Mulligan, Amber N. Stratman, Jianxin A. Yu, Matthew G. Butler
Primitive blood vessels in vertebrate embryos form by a process called vasculogenesis, during which mesodermal cells differentiate into endothelial precursor cells called angioblasts. These angioblasts then differentiate into endothelial cells (ECs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c0b999907fef46d4bb25dc14d4c5ff
https://doi.org/10.1016/b978-0-12-405945-0.00024-7
https://doi.org/10.1016/b978-0-12-405945-0.00024-7
Autor:
Kate G. Ackerman, Peter G. Alexander, Xiaoying Bai, Jennifer L. Baker, David R. Beier, John W. Belmont, David A. Billmire, Ira L. Blitz, Samantha A. Brugmann, Matthew G. Butler, Ching-Fang Chang, Ajay B. Chitnis, William T.Y. Chiu, Ken W.Y. Cho, Albert J. Courey, Damian Dalle Nogare, Jamie Davies, Sheng Ding, Darin Dolezal, Nataki C. Douglas, Hongling Du, Benjamin Feldman, Alejandra Fernandez, Maureen Gannon, Mor Grinstein, Yanli Guo, Renée V. Hoch, Keiji Itoh, Beverly A. Karpinski, Matthew W. Kelley, Kristy L. Kenyon, Paul A. Krieg, Anthony-Samuel LaMantia, Mark T. Langhans, Ke Li, Frederick J. Livesey, Mui Luong, Shawn M. Luttrell, Nasir Malik, Zoë F. Mann, Nathan Martin, Thomas M. Maynard, Roberto Mayor, Daniel Meechan, Sigolène M. Meilhac, Anna M. Method, Sally A. Moody, Steven Moore, Timothy S. Mulligan, L.A. Naiche, Virginia E. Papaioannou, Aitana Perea-Gomez, Francesca Pignoni, Mahendra S. Rao, Girish S. Ratnaparkhi, Kimberly G. Riley, Jean-Pierre Saint-Jeannet, Eric T. Sause, Elizabeth N. Schock, Thomas M. Schultheiss, Soojung Shin, Sergei Y. Sokol, Philippe Soriano, Amber N. Stratman, Billie J. Swalla, Hugh S. Taylor, Irma Thesleff, Eric Theveneau, Rocky S. Tuan, Andrea S. Viczian, Andrew S. Warkman, Andrew J. Washkowitz, Brant M. Weinstein, James M. Wells, Marcin Wlizla, Min Xie, Yingzi Yang, Jianxin A. Yu, Mingliang Zhang, Irene E. Zohn, Leonard I. Zon, Aaron M. Zorn, Michael E. Zuber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::257f1eff6dfdbe58418a507ef8d29cd5
https://doi.org/10.1016/b978-0-12-405945-0.01002-4
https://doi.org/10.1016/b978-0-12-405945-0.01002-4
Publikováno v:
Microvascular research. 96
Recently the zebrafish has emerged as a promising vertebrate model of lymphatic vasculature development. The establishment of numerous transgenic lines that label the lymphatic endothelium in the zebrafish has allowed the fine examination of the deve
Autor:
Robert S. Liwski, Brant M. Weinstein, Anthony Anselmo, John C. Moore, David M. Langenau, Nora Torres Yordán, Riadh Lobbardi, John F. Rawls, Jason N. Berman, Ashwin Ramakrishnan, Qin Tang, Ruslan I. Sadreyev, Timothy S. Mulligan, Finola E. Moore
Publikováno v:
Cancer Research. 76:4177-4177
Cell transplantation into immune compromised mice has transformed our understanding of cancer and is now the gold standard for assessing therapeutic responses in vivo. However, mouse models are expensive and engraftment is often difficult to visualiz