Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Timothy S. Dutill"'
Autor:
Michelle C. Archer, Joseph McCollum, Christopher Press, Timothy S. Dutill, Hong Liang, Dawn Fedor, Liam Kapilow-Cohen, Alana Gerhardt, Tony Phan, Edward H. Trappler, Mark T. Orr, Ryan M. Kramer, Christopher B. Fox
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17325- (2023)
With the recent exception of coronavirus disease 2019 (COVID-19), tuberculosis (TB) causes more deaths globally than any other infectious disease, and approximately 1/3 of the world's population is infected with Mycobacterium tuberculosis (Mtb). Howe
Externí odkaz:
https://doaj.org/article/88a87a77075d4c7299e7f265a7c71fc3
Autor:
Timothy S. Dutill, Michelle C. Archer, Joseph McCollum, Chris Press, Lisa McNeill, Linda Hawkins, Tony Phan, Erik D. Laursen, Richard Cabullos, Lisa Bouchard, Regie J. Castro, Mong-Wu Lin, Jeralyn Roco, Cecile Blois, Babatunde A. Adeagbo, Jeffrey A. Guderian, Alana Gerhardt, Anna Marie Beckmann, Edward H. Trappler, Ryan M. Kramer, Christopher B. Fox
Publikováno v:
Frontiers in Drug Delivery. 2
Promising clinical efficacy results have generated considerable enthusiasm for the potential impact of adjuvant-containing subunit tuberculosis vaccines. The development of a thermostable tuberculosis vaccine formulation could have significant benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf232176abd7a50242b9107e7814b9d
https://doi.org/10.3389/fddev.2022.1043756
https://doi.org/10.3389/fddev.2022.1043756
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964437
Lyophilization of vaccines is advantageous for the distribution and storage of thermally labile products, particularly in regions where cold chain management is difficult. To date, current lyophilized vaccines do not contain an adjuvant. Instead, adj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9418ee3b5d2507d7dbb63b8cf891b07c
https://doi.org/10.1007/978-1-4939-6445-1_15
https://doi.org/10.1007/978-1-4939-6445-1_15
Autor:
Steven G. Reed, James Chesko, Rhea N. Coler, Timothy S. Dutill, Christopher B. Fox, Ryan C. Anderson, Martin Friede, Thomas S. Vedvick, Garrett R. Poshusta, Tara Evers, Narek Shaverdian
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 75:123-132
Immunostimulatory molecules such as monophosphoryl lipid A (MPL), a Toll-like receptor 4 (TLR4) agonist, can be formulated to enhance vaccine adjuvant effects and to promote a Th1-type immune response. This study compares the in vitro and in vivo pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b56a91b11c1cfe5edd8741620c53244
https://doi.org/10.1016/j.colsurfb.2009.08.022
https://doi.org/10.1016/j.colsurfb.2009.08.022
Autor:
Steven G. Reed, Ryan C. Anderson, Christopher B. Fox, Thomas S. Vedvick, Timothy S. Dutill, Yasuyuki Goto
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 65:98-105
Oil-in-water emulsions have shown promise as safe and effective adjuvant formulations for vaccines. In particular, formulations consisting of metabolizable oils such as shark-derived squalene and detergents such as egg phosphatidylcholine have been u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7501f2f5043a6a33218bb32d7c50cd59
https://doi.org/10.1016/j.colsurfb.2008.03.003
https://doi.org/10.1016/j.colsurfb.2008.03.003
Autor:
Steven G. Reed, Sandra J. Sivananthan, Timothy S. Dutill, Susan Lin, Christopher B. Fox, Thomas S. Vedvick, Kristen T Forseth
Publikováno v:
Pharmaceutical development and technology. 16(5)
Development and characterization of stable and biocompatible oil-in-water emulsions is important for improved drug and vaccine delivery. In this work, two-component emulsions consisting of squalene and phosphatidylcholine have been developed. The rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58286c0f185b5107ec910bb5cab945af
https://pubmed.ncbi.nlm.nih.gov/20550484
https://pubmed.ncbi.nlm.nih.gov/20550484