Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Timothy S. Collier"'
Autor:
Anamika Gangwar, Sneha S. Deodhar, Suzanne Saldanha, Olle Melander, Fahim Abbasi, Ryan W. Pearce, Timothy S. Collier, Michael J. McPhaul, Jeremy D. Furtado, Frank M. Sacks, Nathaniel J. Merrill, Jason E. McDermott, John T. Melchior, Anand Rohatgi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15526 (2023)
High-density lipoproteins (HDLs) are promising targets for predicting and treating atherosclerotic cardiovascular disease (ASCVD), as they mediate removal of excess cholesterol from lipid-laden macrophages that accumulate in the vasculature. This fun
Externí odkaz:
https://doaj.org/article/d54832be9c494103b706d50334610c81
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 108:42-51
Context The mechanisms leading to increased cardiovascular disease in patients with nonalcoholic fatty liver disease (NAFLD) and advanced liver fibrosis remain incompletely understood. Objective This study assessed HDL-bound proteins in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c6eb452c8f2f6801be2ebaf06315b3
https://doi.org/10.1210/clinem/dgac565
https://doi.org/10.1210/clinem/dgac565
Autor:
Ashley E, Martinez, Gali, Weissberger, Zsuzsanna, Kuklenyik, Xulei, He, Cristiana, Meuret, Trusha, Parekh, Jon C, Rees, Bryan A, Parks, Michael S, Gardner, Sarah M, King, Timothy S, Collier, Michael G, Harrington, Melanie D, Sweeney, Xinhui, Wang, Berislav V, Zlokovic, Elizabeth, Joe, Daniel A, Nation, Lon S, Schneider, Helena C, Chui, John R, Barr, S Duke, Han, Ronald M, Krauss, Hussein N, Yassine
Publikováno v:
Alzheimer's & Dementia. 19:391-404
We propose the hypothesis that small high-density lipoprotein (HDL) particles reduce the risk of Alzheimer's disease (AD) by virtue of their capacity to exchange lipids, affecting neuronal membrane composition and vascular and synaptic functions. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ff622acb53f5c7095a8e774fa4786a
https://doi.org/10.1002/alz.12649
https://doi.org/10.1002/alz.12649
Autor:
FERNANDO BRIL, RYAN PEARCE, TIMOTHY S. COLLIER, SRILAXMI KALAVALAPALLI, MICHAEL J. MCPHAUL, KENNETH CUSI
Publikováno v:
Diabetes. 71
Patients with T2D remain at high risk of cardiovascular (CV) events despite adequate glycemic and LDL-C control. Changes in HDL particle composition and function may explain part of this increased CV risk. The aim of this study was to determine the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4cf12469854434eb0e8149c50c1bfc0
https://doi.org/10.2337/db22-210-or
https://doi.org/10.2337/db22-210-or
Autor:
Hanna K. Gaggin, Pradeep Natarajan, Cian P. McCarthy, Timothy S. Collier, Ralph B. D'Agostino, Renata Mukai, Asya Lyass, Nasrien E. Ibrahim, Yiwei Li, Marc S. Penn, Joseph M. Massaro, Cory Bystrom, James L. Januzzi, Zhicheng Jin
Publikováno v:
Journal of the American College of Cardiology. 73(17)
Concentrations of circulating apolipoproteins are strongly linked to risk for coronary artery disease (CAD). The relative importance of the additional knowledge of apolipoprotein concentrations within specific lipoprotein species for CAD risk predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba78db13ee8bbe3f3b14e322303bd15
https://pubmed.ncbi.nlm.nih.gov/31047002
https://pubmed.ncbi.nlm.nih.gov/31047002
Autor:
Timothy S. Collier, Sophia Apostolidou, Bruce M. McManus, Robert Balshaw, Darlene L.Y. Dai, Cory E. Bystrom, Marc S. Penn, Zhicheng Jin, Virginia Chen, Raymond T. Ng, Zsuzsanna Hollander
Publikováno v:
Clinical chemistry. 65(2)
BACKGROUND Cholesterol efflux capacity (CEC) is a measure of HDL function that, in cell-based studies, has demonstrated an inverse association with cardiovascular disease. The cell-based measure of CEC is complex and low-throughput. We hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d1e19cc032f2a01ab9020a4f35a3ba
https://pubmed.ncbi.nlm.nih.gov/30523200
https://pubmed.ncbi.nlm.nih.gov/30523200
Publikováno v:
Journal of proteome research. 17(3)
Isolation of high density lipoproteins (HDL) for structural and functional studies typically relies on ultracentrifugation techniques, which are time-consuming and difficult to scale. With emerging interest in the clinical relevance of HDL structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198be26ab52239a319f2a0b260211c20
https://pubmed.ncbi.nlm.nih.gov/29411613
https://pubmed.ncbi.nlm.nih.gov/29411613
Publikováno v:
ELECTROPHORESIS. 35:3463-3469
Altered protein phosphorylation is a feature of many human cancers that can be targeted therapeutically. Phosphopeptide enrichment is a critical step for maximizing the depth of phosphoproteome coverage by MS, but remains challenging for tissue speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5f6c3049ee8bbb363346162b882264
https://doi.org/10.1002/elps.201400022
https://doi.org/10.1002/elps.201400022
Autor:
Timothy S. Collier, Shan M. Randall, Adam Mischler, Karen F. Dorman, Balaji M. Rao, Kim A. Boggess, David C. Muddiman, Prasenjit Sarkar
Publikováno v:
Journal of proteome research. 15(8)
Human embryonic stem cells (hESCs) have been used to derive trophoblasts through differentiation in vitro. Intriguingly, mouse ESCs are prevented from differentiation to trophoblasts by certain epigenetic factor proteins such as Dnmt1, thus necessita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ef0c0af9bacadf6f9539e2ae6d7678
https://pubmed.ncbi.nlm.nih.gov/27378238
https://pubmed.ncbi.nlm.nih.gov/27378238
Autor:
Timothy S. Collier, Balaji M. Rao, Shan M. Randall, Ralph A. Dean, David C. Muddiman, Prasenjit Sarkar
Publikováno v:
Rapid Communications in Mass Spectrometry. 25:2524-2532
Protein quantification is one of the principal goals of mass spectrometry (MS)-based proteomics, and many strategies exist to achieve it. Several approaches involve the incorporation of a stable-isotope label using either chemical derivatization, enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a09d8a9019814dee6fbb76164da224
https://doi.org/10.1002/rcm.5151
https://doi.org/10.1002/rcm.5151