Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Timothy S. Baker"'
Autor:
Rohit H. Subramanian, Sarah J. Smith, Robert G. Alberstein, Jake B. Bailey, Ling Zhang, Giovanni Cardone, Lauri Suominen, Mohamed Chami, Henning Stahlberg, Timothy S. Baker, F. Akif Tezcan
Publikováno v:
ACS Central Science, Vol 4, Iss 11, Pp 1578-1586 (2018)
Externí odkaz:
https://doaj.org/article/d5650ff98fc34885a71646c140838313
Autor:
Yong Zi Tan, Sriram Aiyer, Mario Mietzsch, Joshua A. Hull, Robert McKenna, Joshua Grieger, R. Jude Samulski, Timothy S. Baker, Mavis Agbandje-McKenna, Dmitry Lyumkis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Single-particle cryo-EM is a powerful method for macromolecular structure determination. Here the authors demonstrate that Ewald sphere curvature correction, sub-Angstrom pixilation and per-particle CTF refinement can improve map quality and resoluti
Externí odkaz:
https://doaj.org/article/f000b02747a14526ae63d8ed17d8476c
Autor:
Longfa Xu, Qingbing Zheng, Shaowei Li, Maozhou He, Yangtao Wu, Yongchao Li, Rui Zhu, Hai Yu, Qiyang Hong, Jie Jiang, Zizhen Li, Shuxuan Li, Huan Zhao, Lisheng Yang, Wangheng Hou, Wei Wang, Xiangzhong Ye, Jun Zhang, Timothy S. Baker, Tong Cheng, Z. Hong Zhou, Xiaodong Yan, Ningshao Xia
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Coxsackievirus A6 (CVA6) causes hand, foot and mouth disease in children. Here the authors present the CVA6 procapsid and A-particle cryo-EM structures and identify an immune-dominant neutralizing epitope, which can be exploited for vaccine developme
Externí odkaz:
https://doaj.org/article/f06de03619794e4cae31c9264a758c1f
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6182-6199 (2015)
Sindbis virus (SINV) is an enveloped, mosquito-borne alphavirus. Here we generated and characterized a fluorescent protein-tagged (FP-tagged) SINV and found that the presence of the FP-tag (mCherry) affected glycoprotein transport to the plasma membr
Externí odkaz:
https://doaj.org/article/69f9f915c153450dbdfd21f33f02552a
Autor:
Zhihai Li, Daning Wang, Ying Gu, Shuo Song, Maozhou He, Jingjie Shi, Xinlin Liu, Shuangping Wei, Jinjin Li, Hai Yu, Qingbing Zheng, Xiaodong Yan, Timothy S. Baker, Jun Zhang, Jason S. McLellan, Shaowei Li, Ningshao Xia
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT Persistent, high-risk human papillomavirus (HPV) infection is the primary cause of cervical cancer. Neutralizing antibodies elicited by L1-only virus-like particles (VLPs) can block HPV infection; however, the lack of high-resolution structu
Externí odkaz:
https://doaj.org/article/8f49676155a44406a4ecc5706e4f012c
Autor:
Nikéa Pittman, Adam Misseldine, Lorena Geilen, Sujata Halder, J. Kennon Smith, Justin Kurian, Paul Chipman, Mandy Janssen, Robert Mckenna, Timothy S. Baker, Anthony D’Abramo Jr., Susan Cotmore, Peter Tattersall, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 9, Iss 11, p 321 (2017)
LuIII, a protoparvovirus pathogenic to rodents, replicates in human mitotic cells, making it applicable for use to kill cancer cells. This virus group includes H-1 parvovirus (H-1PV) and minute virus of mice (MVM). However, LuIII displays enhanced on
Externí odkaz:
https://doaj.org/article/b036ccfcc40b4c499f9922879e35ccf3
Autor:
Kristin N. Parent, Yuko Takagi, Giovanni Cardone, Norman H. Olson, Maria Ericsson, May Yang, Yujin Lee, John M. Asara, Raina N. Fichorova, Timothy S. Baker, Max L. Nibert
Publikováno v:
mBio, Vol 4, Iss 2 (2013)
ABSTRACT The flagellated protozoan Trichomonas vaginalis is an obligate human genitourinary parasite and the most frequent cause of sexually transmitted disease worldwide. Most clinical isolates of T. vaginalis are persistently infected with one or m
Externí odkaz:
https://doaj.org/article/0d3db788b4904565a0ae4780d942dc15
Autor:
Richard Henderson, Timothy S. Baker
Publikováno v:
International Tables for Crystallography ISBN: 9780470660782
Burger's Medicinal Chemistry and Drug Discovery
Burger's Medicinal Chemistry and Drug Discovery
This chapter gives a complete but concise introduction to electron cryomicroscopy. The theoretical and practical background is discussed together with a review of applications to the three-dimensional structural analysis of biological macromolecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfe5d3087fd999e50c9843baa93e1b9
https://escholarship.org/uc/item/9tb0m9b8
https://escholarship.org/uc/item/9tb0m9b8
Autor:
Rohit H. Subramanian, Jake B. Bailey, Xiaodong Yan, Timothy S. Baker, Timothy Booth, F. Akif Tezcan, Jerika A. Chiong, Robert G. Alberstein, Julian Esselborn, Eyal Golub
Publikováno v:
Nature
Nature, vol 578, iss 7793
Nature, vol 578, iss 7793
Many proteins exist naturally as symmetrical homooligomers or homopolymers1. The emergent structural and functional properties of such protein assemblies have inspired extensive efforts in biomolecular design2–5. As synthesized by ribosomes, protei
Autor:
Michael C. Fiore, Timothy S. Baker, Robert Adsit, Susan Lundsten, Mark Zehner, Amy D. Skora, Danielle E. McCarthy, Paul Hartlaub, Allison Gorrilla, Todd A. Mahr
Publikováno v:
Journal of the American Medical Informatics Association. 26:778-786
Objective The study sought to determine whether interoperable, electronic health record–based referral (eReferral) produces higher rates of referral and connection to a state tobacco quitline than does fax-based referral, thus addressing low rates