Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Timothy R. Walsh"'
Autor:
Tengfei Ma, Ning Xie, Yuan Gao, Jiani Fu, Chun E. Tan, Qiu E. Yang, Shaolin Wang, Zhangqi Shen, Quanjiang Ji, Julian Parkhill, Congming Wu, Yang Wang, Timothy R. Walsh, Jianzhong Shen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract IncX3 plasmids carrying the New Delhi metallo-β-lactamase-encoding gene, bla NDM-5, are rapidly spreading globally in both humans and animals. Given that carbapenems are listed on the WHO AWaRe watch group and are prohibited for use in anim
Externí odkaz:
https://doaj.org/article/0c8fbbf9704240e494654433d6bec2e6
Autor:
Qiu E. Yang, Xiaodan Ma, Minchun Li, Mengshi Zhao, Lingshuang Zeng, Minzhen He, Hui Deng, Hanpeng Liao, Christopher Rensing, Ville-Petri Friman, Shungui Zhou, Timothy R. Walsh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The horizontal transfer of plasmids has been recognized as one of the key drivers for the worldwide spread of antimicrobial resistance (AMR) across bacterial pathogens. However, knowledge remain limited about the contribution made by environ
Externí odkaz:
https://doaj.org/article/29606563a00d4cd9afaef9ebf5c322c7
Autor:
Maria Nieto-Rosado, Kirsty Sands, Edward A. R. Portal, Kathryn M. Thomson, Maria J. Carvalho, Jordan Mathias, Rebecca Milton, Calie Dyer, Chinenye Akpulu, Ian Boostrom, Patrick Hogan, Habiba Saif, Ana D. Sanches Ferreira, Thomas Hender, Barbra Portal, Robert Andrews, W. John Watkins, Rabaab Zahra, Haider Shirazi, Adil Muhammad, Syed Najeeb Ullah, Muhammad Hilal Jan, Shermeen Akif, Kenneth C. Iregbu, Fatima Modibbo, Stella Uwaezuoke, Lamidi Audu, Chinago P. Edwin, Ashiru H. Yusuf, Adeola Adeleye, Aisha S. Mukkadas, Jean Baptiste Mazarati, Aniceth Rucogoza, Lucie Gaju, Shaheen Mehtar, Andrew N. H. Bulabula, Andrew Whitelaw, Lauren Roberts, Grace Chan, Delayehu Bekele, Semaria Solomon, Mahlet Abayneh, Gesit Metaferia, Group BARNARDS, Timothy R. Walsh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Hospital surfaces can harbour bacterial pathogens, which may disseminate and cause nosocomial infections, contributing towards mortality in low- and middle-income countries (LMICs). During the BARNARDS study, hospital surfaces from neonatal
Externí odkaz:
https://doaj.org/article/fb3f6d5c019a46c0ac7a6466db812ad7
Autor:
Huangwei Song, Xueyang Wang, Muchen Zhang, Zhiyu Zou, Siyuan Yang, Tian Yi, Jianfeng Wang, Dejun Liu, Yingbo Shen, Chongshan Dai, Zhihai Liu, Timothy R. Walsh, Jianzhong Shen, Congming Wu, Yang Wang
Publikováno v:
Engineering, Vol 32, Iss , Pp 163-173 (2024)
The emergence and spread of the mobile colistin-resistance gene, mcr-1, and its variants pose a challenge to the use of colistin, a last-resort antibiotic used to treat severe infections caused by extensively drug-resistant (XDR) Gram-negative pathog
Externí odkaz:
https://doaj.org/article/fdaad9a2f0f84a748f42b929b5a77592
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28052- (2024)
Background: Carbapenem resistance is epidemic worldwide, these last resort antimicrobials are listed in the WHO ‘watch group’ with higher resistance potential. During the years 2017-18 Pakistan Antimicrobial Resistance Surveillance System reporte
Externí odkaz:
https://doaj.org/article/2e91e222ec0a4d3cba5caaa09d6b9161
Autor:
Sharmi Naha, Priyanka Basak, Kirsty Sands, Rebecca Milton, Maria J. Carvalho, Shravani Mitra, Amrita Bhattacharjee, Anuradha Sinha, Suchandra Mukherjee, Bijan Saha, Pinaki Chattopadhyay, Partha Sarathi Chakravorty, Ranjan Kumar Nandy, Shanta Dutta, Timothy R. Walsh, Sulagna Basu
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Exchange of antimicrobial resistance genes via mobile genetic elements occur in the gut which can be transferred from mother to neonate during birth. This study is the first to analyse transmissible colistin resistance gene, mcr, in pregnant mothers
Externí odkaz:
https://doaj.org/article/86ff746e48e14f7e8303f4309e0848a3
Autor:
Yingbo Shen, Rong Zhang, Dongyan Shao, Lu Yang, Jiayue Lu, Congcong Liu, Xueyang Wang, Junyao Jiang, Boxuan Wang, Congming Wu, Julian Parkhill, Yang Wang, Timothy R. Walsh, George F. Gao, Zhangqi Shen
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 6, Pp 1168-1179 (2022)
Emergence of the colistin resistance gene, mcr-1, has attracted worldwide attention. Despite the prevalence of mcr-1-positive Escherichia coli (MCRPEC) strains in human carriage showing a significant decrease between 2016 and 2019, genetic difference
Externí odkaz:
https://doaj.org/article/077857d4ac6d4763a757bd3ccd382499
Publikováno v:
PLoS Medicine, Vol 20, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/a8f5579a6e3646ea882610e5997a1acc
Autor:
Bo Fu, Jian Xu, Dandan Yin, Chengtao Sun, Dejun Liu, Weishuai Zhai, Rina Bai, Yue Cao, Qin Zhang, Shizhen Ma, Timothy R. Walsh, Fupin Hu, Yang Wang, Congming Wu, Jianzhong Shen
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTDespite carbapenems not being used in animals, carbapenem-resistant Enterobacterales (CRE), particularly New Delhi metallo-β-lactamase-producing CRE (NDM-CRE), are prevalent in livestock. Concurrently, the incidence of human infections cause
Externí odkaz:
https://doaj.org/article/a141bb1d016f458994a2d9acbb3f7ea2
Autor:
Yuqing Zhou, Refath Farzana, Somsavanh Sihalath, Sayaphet Rattanavong, Manivanh Vongsouvath, Mayfong Mayxay, Kirsty Sands, Paul N. Newton, David A.B. Dance, Brekhna Hassan, Timothy R. Walsh
Publikováno v:
Engineering, Vol 15, Iss , Pp 45-56 (2022)
This study was designed to investigate the molecular epidemiology of mobile colistin resistance (mcr) using a “One-Health” approach in Laos and to predict whether any dominant plasmid backbone and/or strain type influences the dissemination of mc
Externí odkaz:
https://doaj.org/article/16f1920b8e334155977d0c4d8150de1b