Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Timothy R. Wagenaar"'
Autor:
Marie Bernardo, Tatiana Tolstykh, Yu-an Zhang, Dinesh S. Bangari, Hui Cao, Kerstin A. Heyl, Joon Sang Lee, Natalia V. Malkova, Katie Malley, Eladio Marquez, Jack Pollard, Hui Qu, Errin Roberts, Sue Ryan, Kuldeep Singh, Fangxian Sun, Emma Wang, Keith Bahjat, Dmitri Wiederschain, Timothy R. Wagenaar
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Immune checkpoint blockade elicits durable anti-cancer responses in the clinic, however a large proportion of patients do not benefit from treatment. Several mechanisms of innate and acquired resistance to checkpoint blockade have been defined and in
Externí odkaz:
https://doaj.org/article/656d0612e4934ba88e1213a45e27d794
Autor:
Virna Cortez-Retamozo, Donald Shaffer, Katalin Karikó, Marie Bernardo, Timothy R Wagenaar, Hossam Hefesha, Mikhail Levit, Isaac Esparza, Ferdia Bates, Kerstin Andrea Heyl, Christian Hotz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/faf6bfc237cf45199169736f084cc1bd
Autor:
Dmitri Wiederschain, Gang Zheng, Qunyan Yu, Eunsil Yu, Christopher Winter, William Weber, Tatiana Tolstykh, Fangxian Sun, Chaomei Shi, Sabine Scheidler, Jennifer L. Rocnik, Jason Reeves, Jack Pollard, Adam Pavlicek, Christiane Metz-Weidmann, Deokhoon Kim, Lan Jiang, Shih-Min A. Huang, Rajula Gaur, Carlos Garcia-Echeverria, Scott Davis, Hui Cao, Raffaele Baffa, Heike Arlt, Charles Allerson, Sung-Min Ahn, Sonya Zabludoff, Timothy R. Wagenaar
Supplementary Tables 1 and 2. Supplementary Table 1: Fold de-repression of miR-21 target genes after anti-miR-21 treatment. Supplementary Table 2: Taqman Primer and Probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8432729fffeac16eb696d8676f243bbc
https://doi.org/10.1158/1541-7786.22513665.v1
https://doi.org/10.1158/1541-7786.22513665.v1
Autor:
Dmitri Wiederschain, Gang Zheng, Qunyan Yu, Eunsil Yu, Christopher Winter, William Weber, Tatiana Tolstykh, Fangxian Sun, Chaomei Shi, Sabine Scheidler, Jennifer L. Rocnik, Jason Reeves, Jack Pollard, Adam Pavlicek, Christiane Metz-Weidmann, Deokhoon Kim, Lan Jiang, Shih-Min A. Huang, Rajula Gaur, Carlos Garcia-Echeverria, Scott Davis, Hui Cao, Raffaele Baffa, Heike Arlt, Charles Allerson, Sung-Min Ahn, Sonya Zabludoff, Timothy R. Wagenaar
Supplementary Figure Legends. Figure legends for Supplementary Figures 1, 2, 3, and 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788f3132371a9c1df7ec4e32df1cd3f4
https://doi.org/10.1158/1541-7786.22513668.v1
https://doi.org/10.1158/1541-7786.22513668.v1
Autor:
Dmitri Wiederschain, Gang Zheng, Qunyan Yu, Eunsil Yu, Christopher Winter, William Weber, Tatiana Tolstykh, Fangxian Sun, Chaomei Shi, Sabine Scheidler, Jennifer L. Rocnik, Jason Reeves, Jack Pollard, Adam Pavlicek, Christiane Metz-Weidmann, Deokhoon Kim, Lan Jiang, Shih-Min A. Huang, Rajula Gaur, Carlos Garcia-Echeverria, Scott Davis, Hui Cao, Raffaele Baffa, Heike Arlt, Charles Allerson, Sung-Min Ahn, Sonya Zabludoff, Timothy R. Wagenaar
Supplementary Data 1. Excel sheet with fold change in gene expression following anti-miR-21 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e95a7f6cd9f6105c850d7e3c0ce479e
https://doi.org/10.1158/1541-7786.22513683
https://doi.org/10.1158/1541-7786.22513683
Autor:
Dmitri Wiederschain, Gang Zheng, Qunyan Yu, Eunsil Yu, Christopher Winter, William Weber, Tatiana Tolstykh, Fangxian Sun, Chaomei Shi, Sabine Scheidler, Jennifer L. Rocnik, Jason Reeves, Jack Pollard, Adam Pavlicek, Christiane Metz-Weidmann, Deokhoon Kim, Lan Jiang, Shih-Min A. Huang, Rajula Gaur, Carlos Garcia-Echeverria, Scott Davis, Hui Cao, Raffaele Baffa, Heike Arlt, Charles Allerson, Sung-Min Ahn, Sonya Zabludoff, Timothy R. Wagenaar
Supplementary Figure 1. miR-21 mimic suppresses expression of ANKRD46, DDAH1 and RECK. SKHep1 cells were transfected with miR-21 or negative mimic. RNA was isolated and expression of ANKRD46, DDAH1 and RECK was assessed by qPCR. (Mean, {plus minus} S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e12d835254440df0d4d0e34c3f2131
https://doi.org/10.1158/1541-7786.22513680
https://doi.org/10.1158/1541-7786.22513680
Autor:
Dmitri Wiederschain, Gang Zheng, Qunyan Yu, Eunsil Yu, Christopher Winter, William Weber, Tatiana Tolstykh, Fangxian Sun, Chaomei Shi, Sabine Scheidler, Jennifer L. Rocnik, Jason Reeves, Jack Pollard, Adam Pavlicek, Christiane Metz-Weidmann, Deokhoon Kim, Lan Jiang, Shih-Min A. Huang, Rajula Gaur, Carlos Garcia-Echeverria, Scott Davis, Hui Cao, Raffaele Baffa, Heike Arlt, Charles Allerson, Sung-Min Ahn, Sonya Zabludoff, Timothy R. Wagenaar
Supplementary Figure 4. Pathway analysis of gene expression changes following anti-miR-21 treatment. SKHep1 cells treated with anti-miR-21 were subjected to microarray gene expression analysis. Changes in cellular processes (top) and pathways (bottom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cfd6e6221e3b1bc696d8dfaccbeac4
https://doi.org/10.1158/1541-7786.22513671.v1
https://doi.org/10.1158/1541-7786.22513671.v1
Autor:
Lars M. König, Bodo Brunner, Simon Rothenfußer, Sabine Scheidler, Dmitri Wiederschain, Stefan Endres, Max M. Schnurr, Timothy R. Wagenaar, Hui Cao, Joachim Theilhaber, Kaj Grandien, Petra Scherer, Gabriele Dietert, Monika Braun, Christiane Metz-Weidmann, Felix Gnerlich, Kerstin Jahn-Hofmann, Mike W. Helms
Supplementary Figure S1 shows that RIG-I, MDA and IRF7 mRNA expression are correlated to the Type I IFN signature in melanoma, while MAVS, TBK1 and IRF3 are not. Supplementary Figure S2 shows a list of gene products correlated with RIG-I expression b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a4da953aaf859e66a4a0df15ab8f8b
https://doi.org/10.1158/1535-7163.22505878.v1
https://doi.org/10.1158/1535-7163.22505878.v1
Autor:
Dmitri Wiederschain, Gang Zheng, Qunyan Yu, Eunsil Yu, Christopher Winter, William Weber, Tatiana Tolstykh, Fangxian Sun, Chaomei Shi, Sabine Scheidler, Jennifer L. Rocnik, Jason Reeves, Jack Pollard, Adam Pavlicek, Christiane Metz-Weidmann, Deokhoon Kim, Lan Jiang, Shih-Min A. Huang, Rajula Gaur, Carlos Garcia-Echeverria, Scott Davis, Hui Cao, Raffaele Baffa, Heike Arlt, Charles Allerson, Sung-Min Ahn, Sonya Zabludoff, Timothy R. Wagenaar
Supplementary Figure 2. Anti-miR-21 treatment causes limited caspase 3/7 activation in non-transformed cell lines. Caspase 3/7 activation after treatment of SKHep1, IMR-90, and WI-38 cells with MM control or anti-miR-21 for 72 hours. (Mean, {plus min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef8d998ef87d171dc8082119bf325ba
https://doi.org/10.1158/1541-7786.22513677
https://doi.org/10.1158/1541-7786.22513677
Autor:
Lars M. König, Timothy R. Wagenaar, Simon Rothenfußer, Monika Braun, Hui Cao, Christiane Metz-Weidmann, Gabriele Dietert, Sabine Scheidler, Max Schnurr, Kaj Grandien, Felix Gnerlich, Dmitri Wiederschain, Joachim Theilhaber, Stefan Endres, Kerstin Jahn-Hofmann, Mike W. Helms, Petra Scherer, Bodo Brunner
Publikováno v:
Molecular Cancer Therapeutics. 18:2343-2356
The pattern recognition receptor RIG-I plays an important role in the recognition of nonself RNA and antiviral immunity. RIG-I's natural ligand, triphosphate RNA (ppp-RNA), is proposed to be a valuable addition to the growing arsenal of cancer immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe637e7d26f0964569f49676c0e5b05c
https://doi.org/10.1158/1535-7163.mct-18-1262
https://doi.org/10.1158/1535-7163.mct-18-1262