Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Timothy R. Mhyre"'
Autor:
Dawn eBeraud, Margaret eTwomey, Benjamin eBloom, Andrew eMittereder, Katherine eNeitzke, Vy eTon, Sergey eChasovskikh, Timothy R. Mhyre, Kathleen A. Maguire-Zeiss
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
Parkinson’s disease, an age-related neurodegenerative disorder, is characterized by the loss of dopamine neurons in the substantia nigra, the accumulation of α-synuclein in Lewy bodies and neurites, and neuroinflammation. While the exact etiology
Externí odkaz:
https://doaj.org/article/a3a86dd551ae411d98cc3f13c4f5e0ba
Autor:
Andrew Serour, Christopher C. Leonardo, Elizabeth Kriscenski-Perry, David A. Pearce, Timothy R. Mhyre, Craig D. Applegate
Publikováno v:
Epilepsia. 43:1137-1140
Summary: Purpose: Juvenile neuronal ceroid lipofuscinosis (JNCL), or Batten disease, is a pediatric neurodegenerative disease characterized by vision loss, seizure activity, cognitive decline, and premature death. Discovery of the Batten disease–re
Autor:
Robert Padilla, Colin G. DeYoung, Jeremy R. Gray, G. William Rebeck, Timothy R. Mhyre, Amanda M. DiBattista, Adam E. Green
A recent history of failed clinical trials suggests that waiting until even the early stages of onset of Alzheimer's disease may be too late for effective treatment, pointing to the importance of early intervention in young people. Early intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e57bcb532b9d07da659ec5852775639
https://europepmc.org/articles/PMC4420146/
https://europepmc.org/articles/PMC4420146/
Publikováno v:
Journal of Neurobiology. 42:134-147
The properties of depolarization-evoked calcium transients are known to change during the maturation of dissociated cerebellar granule neuron cultures. Here, we assessed the role of the calcium-induced calcium release (CICR) mechanism in granule neur
Autor:
Susan G. Fisher, Carrie B. Peltz, Timothy R. Mhyre, Mark Mapstone, Derick R. Peterson, Michael Nazar, Dan J Berlau, William J. Hall, Ming Tan, Massimo S. Fiandaca, Claudia H. Kawas, Howard J. Federoff, Steven A. Rich, Linda MacArthur, Amrita K. Cheema, James M Haley, Xiaogang Zhong
Publikováno v:
Mapstone, M; Cheema, AK; Fiandaca, MS; Zhong, X; Mhyre, TR; Macarthur, LH; et al.(2014). Plasma phospholipids identify antecedent memory impairment in older adults. Nature Medicine, 20(4), 415-418. doi: 10.1038/nm.3466. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/50n9b66b
Alzheimer's disease causes a progressive dementia that currently affects over 35 million individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no cures or disease-modifying therapies, and this may be due to our inabi
Autor:
Sona Vasudevan, Elenora Connors, Elliott Crooke, Timothy R. Mhyre, Howard J. Federoff, Linda MacArthur
Publikováno v:
Handbook of Systems and Complexity in Health ISBN: 9781461449973
In 2003, Dr. Elias Zerhouni created the National Institutes of Health (NIH) roadmap and articulated an agenda to aggressively pursue a more integrated approach to use research discoveries to impact human health. Working groups focused on three major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed4b0d49bfd4a54e68426f46294f2cd
https://doi.org/10.1007/978-1-4614-4998-0_51
https://doi.org/10.1007/978-1-4614-4998-0_51
Autor:
Mika Shimoji, Howard J. Federoff, Hannah A. Hathaway, Sergey Chasovskikh, Dawn Béraud, Timothy R. Mhyre, Kathleen A. Maguire-Zeiss, Jordan Trecki, Jeffrey A. Johnson, Delinda A. Johnson
Publikováno v:
Journal of Neuroimmune Pharmacology
Béraud, D; Hathaway, HA; Trecki, J; Chasovskikh, S; Johnson, DA; Johnson, JA; et al.(2013). Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein. Journal of Neuroimmune Pharmacology, 8(1), 94-117. doi: 10.1007/s11481-012-9401-0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/27k6435n
Béraud, D; Hathaway, HA; Trecki, J; Chasovskikh, S; Johnson, DA; Johnson, JA; et al.(2013). Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein. Journal of Neuroimmune Pharmacology, 8(1), 94-117. doi: 10.1007/s11481-012-9401-0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/27k6435n
Parkinson's disease (PD) is the second most common age-related neurodegenerative disorder typified by tremor, rigidity, akinesia and postural instability due in part to the loss of dopamine within the nigrostriatal system. The pathologic features of
Publikováno v:
Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease ISBN: 9789400754157
Parkinson’s disease (PD) is the most common age-related motoric neurodegenerative disease initially described in the 1800’s by James Parkinson as the ‘Shaking Palsy’. Loss of the neurotransmitter dopamine was recognized as underlying the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19baa21eaffdc3f7af0e73c19f948f59
https://doi.org/10.1007/978-94-007-5416-4_16
https://doi.org/10.1007/978-94-007-5416-4_16
Autor:
Sergey Chasovskikh, Andrew Mittereder, Timothy R. Mhyre, Vy Ton, Kathleen A. Maguire-Zeiss, Dawn Béraud, Margaret A. Twomey, Benjamin Bloom, Katherine Neitzke
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
Frontiers in Neuroscience
Frontiers in Neuroscience
Parkinson’s disease, an age-related neurodegenerative disorder, is characterized by the loss of dopamine neurons in the substantia nigra, the accumulation of α-synuclein in Lewy bodies and neurites, and neuroinflammation. While the exact etiology
Autor:
Valeriya Avdoshina, Timothy R. Mhyre, Maia Parsadanian, Lino Tessarollo, Lee A. Campbell, Jody Becker, Italo Mocchetti
In the central nervous system, chemokines are primarily mediators of inflammatory processes. Their receptors, in particular, CXCR4 and CCR5, serve as co-factors along with CD4 that permit Human immunodeficiency virus-1 (HIV) infection. Moreover, expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae05fe709b5158e9db518a87c26d3440
https://europepmc.org/articles/PMC3077968/
https://europepmc.org/articles/PMC3077968/