Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Timothy R. Koscik"'
Autor:
Ashrita Raghuram, Alberto Varon, Jorge A. Roa, Daizo Ishii, Yongjun Lu, Madhavan L. Raghavan, Chaorong Wu, Vincent A. Magnotta, David M. Hasan, Timothy R. Koscik, Edgar A. Samaniego
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Aneurysm wall enhancement (AWE) after the administration of contrast gadolinium is a potential biomarker of unstable intracranial aneurysms. While most studies determine AWE subjectively, this study comprehensively quantified AWE in 3D imagi
Externí odkaz:
https://doaj.org/article/8d7fdb47d4564afb9dffc9e1c868ccff
Autor:
Ashrita Raghuram, Alberto Varon, Sebastian Sanchez, Daizo Ishii, Chaorong Wu, Vincent A. Magnotta, David M. Hasan, Timothy R. Koscik, Edgar A. Samaniego
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 2, Iss 4 (2022)
Background Aneurysm wall enhancement has been identified as a potential biomarker for aneurysm instability. Enhancement has been determined by different approaches on 2‐dimensional multiplanar views. This study describes a new method to quantify en
Externí odkaz:
https://doaj.org/article/e01e06a55eba430c8bfbe64f1016399b
Autor:
Timothy R. Koscik, Ellen van der Plas, Laurie Gutmann, Sarah A. Cumming, Darren G. Monckton, Vincent Magnotta, Richard K. Shields, Peggy C. Nopoulos
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Deficits in white matter (WM) integrity and motor symptoms are among the most robust and reproducible features of myotonic dystrophy type 1 (DM1). In the present study, we investigate whether WM integrity, obtained from diffusion-weighted MR
Externí odkaz:
https://doaj.org/article/0e5a87339ef14fe0b3a871680f6a4da9
Autor:
Nicholas T. Trapp, Joel Bruss, Marcie King Johnson, Brandt D. Uitermarkt, Laren Garrett, Amanda Heinzerling, Chaorong Wu, Timothy R. Koscik, Patrick Ten Eyck, Aaron D. Boes
Publikováno v:
Brain Stimulation, Vol 13, Iss 3, Pp 578-581 (2020)
Background: No consensus exists in the clinical transcranial magnetic stimulation (TMS) field as to the best method for targeting the left dorsolateral prefrontal cortex (DLPFC) for depression treatment. Two common targeting methods are the Beam F3 m
Externí odkaz:
https://doaj.org/article/556bc2cd10bf407cbb0052be98949d06
Autor:
Ellen van der Plas, Jeffrey D. Long, Timothy R. Koscik, Vincent Magnotta, Darren G. Monckton, Sarah A. Cumming, Amy C. Gottschalk, Marco Hefti, Laurie Gutmann, Peggy C. Nopoulos
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
IntroductionThe present study had four aims. First, neuronal injury markers, including neurofilament light (NF-L), total tau, glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase (UCH-L1), were compared between individuals with a
Externí odkaz:
https://doaj.org/article/009018d5ab65499fb8768c4ab0e95700
Autor:
Jacob N. Miller, Alison Kruger, David J. Moser, Laurie Gutmann, Ellen van der Plas, Timothy R. Koscik, Sarah A. Cumming, Darren G. Monckton, Peggy C. Nopoulos
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Myotonic dystrophy type 1 is the most common form of muscular dystrophy in adults, and is primarily characterized by muscle weakness and myotonia, yet some of the most disabling symptoms of the disease are cognitive and behavioral. Here we evaluated
Externí odkaz:
https://doaj.org/article/e471c06bf36444afb72579129c838841
Publikováno v:
NeuroImage, Vol 214, Iss , Pp 116764- (2020)
Understanding the neural implementation of value-based choice has been an important focus of neuroscience for several decades. Although a consensus has emerged regarding the brain regions involved, including ventromedial prefrontal cortex (vmPFC), po
Externí odkaz:
https://doaj.org/article/60dc76053947447693e2b62ab074cb1d
Autor:
Jordan L. Schultz, Douglas R. Langbehn, Hend M. Al‐Kaylani, Ellen van der Plas, Timothy R. Koscik, Eric A. Epping, Patricia B. Espe‐Pfeifer, Erin P. Martin, David J. Moser, Vincent A. Magnotta, Peggy C. Nopoulos
Publikováno v:
Movement Disorders. 38:113-122
Juvenile-onset Huntington's disease (JOHD) is a rare form of Huntington's disease (HD) characterized by symptom onset before the age of 21 years. Observational data in this cohort is lacking.Quantify measures of disease progression for use in clinica
Autor:
Erin E. Reasoner, Ellen van der Plas, Douglas R. Langbehn, Amy L. Conrad, Timothy R. Koscik, Eric A. Epping, Vincent A. Magnotta, Peggy C. Nopoulos
Publikováno v:
J Huntingtons Dis
Background: Molecular studies provide evidence that mutant huntingtin (mHTT) affects early cortical development; however, cortical development has not been evaluated in child and adolescent carriers of mHTT. Objective: To evaluate the impact of mHTT
Autor:
Lichun Zhang, Zhihui Guo, Honghai Zhang, Ellen van der Plas, Timothy R. Koscik, Peggy C. Nopoulos, Milan Sonka
Publikováno v:
Medical Physics.