Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Timothy R. Howes"'
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-16 (2017)
Abstract Background Dorsal spine reduction in threespine sticklebacks (Gasterosteus aculeatus) is a classic example of recurrent skeletal evolution in nature. Sticklebacks in marine environments typically have long spines that form part of their skel
Externí odkaz:
https://doaj.org/article/3ef6b1671237400d88a3d07d6e683efa
Autor:
Julia I. Wucherpfennig, Timothy R. Howes, Jessica N. Au, Eric H. Au, Garrett A. Roberts Kingman, Shannon D. Brady, Amy L. Herbert, Thomas E. Reimchen, Michael A. Bell, Craig B. Lowe, Anne C. Dalziel, David M. Kingsley
Publikováno v:
Nature ecologyevolution. 6(10)
Understanding the mechanisms leading to new traits or additional features in organisms is a fundamental goal of evolutionary biology. We show that HOXDB regulatory changes have been used repeatedly in different fish genera to alter the length and num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57012d5b88600494a722dee143dfa2bc
https://pubmed.ncbi.nlm.nih.gov/36050398
https://pubmed.ncbi.nlm.nih.gov/36050398
Autor:
Julia I. Wucherpfennig, Timothy R. Howes, Jessica N. Au, Eric H. Au, Garrett A. Roberts Kingman, Shannon D. Brady, Amy L. Herbert, Thomas E. Reimchen, Michael A. Bell, Craig B. Lowe, Anne C. Dalziel, David M. Kingsley
SummaryUnderstanding the genetic mechanisms leading to new traits is a fundamental goal of evolutionary biology. We show that HOXDB regulatory changes have been used repeatedly in different stickleback fish species to alter the length and number of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467a738d52ffea3010e55fa5203d35f0
https://doi.org/10.1101/2021.12.14.472698
https://doi.org/10.1101/2021.12.14.472698
Autor:
Sarah Warren, Danny Wells, Theresa LaVallee, Tyler Hether, Jason Reeves, Christine N. Spencer, Travis Hollman, Jedd D. Wolchok, Timothy R. Howes, Claire F. Friedman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background NanoString’s GeoMx Digital Spatial Profiling (DSP) technology enables profiling of gene or protein expression from fresh or archival tissues. Specific regions of interest (ROIs) are identified via fluorescently labeled visualization mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9bed1bdc648e74ef2a94fd37659524
https://doi.org/10.1136/jitc-2020-sitc2020.0305
https://doi.org/10.1136/jitc-2020-sitc2020.0305
Autor:
John M. Kirkwood, Lazar Vujanovic, Sarah Warren, Juraj Adamik, Patricia M. Santos, Timothy R. Howes, Samuel W. Du, Andrea Gambotto, Lisa H. Butterfield
Publikováno v:
The Journal of Experimental Medicine
Santos et al. analyze cancer patient vaccine antigen-specific T cells for the importance of immune checkpoint molecule and gene pathway expression. CTLA-4 and PD-1 pathways are significantly correlated to T cell response and clinical outcomes, and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5182dc187ec9e2ac31c8dbd309e703d
http://europepmc.org/articles/PMC7336310
http://europepmc.org/articles/PMC7336310
Autor:
David M. Kingsley, Shannon D. Brady, Michael A. Bell, Timothy R. Howes, Nicelio Sanchez-Luege, Rhea R. Daugherty, Felicity C. Jones, Craig B. Lowe
We present a method to detect copy number variants (CNVs) that are differentially present between two groups of sequenced samples. We use a finite-state transducer where the emitted read depth is conditioned on the mappability and GC-content of all r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66204ba4ee1a110816be6b3b891e75e
https://europepmc.org/articles/PMC5793789/
https://europepmc.org/articles/PMC5793789/
Autor:
David M. Kingsley, Shannon D. Brady, Craig B. Lowe, Rhea R. Daugherty, Michael A. Bell, Timothy R. Howes, Nicelio Sanchez-Luege, Felicity C. Jones
Publikováno v:
Genome Research. 28:766.1-766.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c9a64fea48924f3b9023774e937ae3b
https://doi.org/10.1101/gr.237370.118
https://doi.org/10.1101/gr.237370.118
Autor:
Ross Swofford, Eric S. Lander, Jeremy Schmutz, Jane Grimwood, Timothy R. Howes, Mono Pirun, Anne K. Knecht, Evan Mauceli, Manfred Grabherr, Kerstin Lindblad-Toh, Haili Zhang, Brian R. Summers, Michael C. Zody, Richard M. Myers, Felicity C. Jones, Stephen M. J. Searle, Ewan Birney, Federica Di Palma, Simon D. M. White, Jeremy Johnson, Chris T. Amemiya, David M. Kingsley, Shannon D. Brady, Alex A. Pollen, Mark Dickson, Yingguang Frank Chan, Craig Miller, Pamela Russell
Publikováno v:
Nature, vol 484, iss 7392
PMC
Nature
PMC
Nature
Marine stickleback fish have colonized and adapted to thousands of streams and lakes formed since the last ice age, providing an exceptional opportunity to characterize genomic mechanisms underlying repeated ecological adaptation in nature. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8a84d1833591050a2d2772cce37fff
https://escholarship.org/uc/item/82z6t7n0
https://escholarship.org/uc/item/82z6t7n0