Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Timothy R. Hansen"'
Autor:
Leanna Lagpacan, Christopher Allen Ziebenhaus, Bruno Marchand, Elfatih Elzein, Jason K. Perry, Bernard P. Murray, Scott Preston Simonovich, Parkhill Eric Q, Armando G. Villaseñor, WaiLok K. Hung, Nikos Pagratis, Rao Kalla, Jeff Zablocki, Dmitry Koltun, John R. Somoza, Timothy R. Hansen, Ron Aoyama, Thao Perry, Magdeleine Hung, Xiaofen Li
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(3)
We hereby disclose the discovery of inhibitors of CaMKII (7h and 7i) that are highly potent in rat ventricular myocytes, selective against hERG and other off-target kinases, while possessing good CaMKII tissue isoform selectivity (cardiac γ/δ vs. n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caba80ce7be1413193b5f5243755c5aa
https://pubmed.ncbi.nlm.nih.gov/29254643
https://pubmed.ncbi.nlm.nih.gov/29254643
Autor:
Daniel J. Hicklin, John G.M. Ullman, Elizabeth M. Jaffee, Elizabeth A. Manning, Justin M. Asquith, Todd D. Armstrong, Leisha A. Emens, Timothy R. Hansen, James M. Leatherman
Publikováno v:
Clinical Cancer Research. 13:3951-3959
Purpose: Given the complex tumor microenvironment, targeting multiple cellular components may be the most effective cancer treatment strategy. Therefore, we tested whether antiangiogenic and immune-based therapy might synergize by characterizing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2954deda38179db011d7d4ee80db2bbc
https://doi.org/10.1158/1078-0432.ccr-07-0374
https://doi.org/10.1158/1078-0432.ccr-07-0374
Publikováno v:
Hypertension. 7:333-339
Increased sympathetic outflow from the central nervous system to the periphery may contribute to the initiation of hypertension in spontaneously hypertensive rats (SHR). As this alteration in sympathetic activity may be mediated in part by alpha-adre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a051b81480fa48d767ed9685473aa085
https://doi.org/10.1161/01.hyp.7.3.333
https://doi.org/10.1161/01.hyp.7.3.333
Autor:
Timothy R. Hansen, David F. Bohr
Publikováno v:
Circulation Research. 36:590-598
The effect of transmural pressure on the responsiveness of vascular smooth muscle was studied using rats with chronic occlusion of one external iliac artery. The arterial pressure in the occluded leg was reduced to approximately half of that in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e82fdc4dde0873b7670d744db368455
https://doi.org/10.1161/01.res.36.5.590
https://doi.org/10.1161/01.res.36.5.590
Autor:
Gordon L. Pullen, Morley C. Sutter, Diwan Singh, Money C. Sutter, Farouk El-Sabban, William I. Rosenblum, Timothy R. Hansen, Dennis X. Dineen, Catherine C.Y. Pang
Publikováno v:
Journal of Vascular Research. 17:I-V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc753f48c61b77ecb29daf7f8a7e1c21
https://doi.org/10.1159/000158258
https://doi.org/10.1159/000158258
Publikováno v:
Blood vessels. 17(6)
The functional orientation of vascular smooth muscle in the walls of aortae of DOCA-hypertensive and normotensive rats was determined by measuring the maximum force-generating capacity of strips cut at various angles from their aortae. The greatest t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d7746d360bbf653aad6e70adf1d10e
https://pubmed.ncbi.nlm.nih.gov/7437523
https://pubmed.ncbi.nlm.nih.gov/7437523
Publikováno v:
European journal of pharmacology. 63(2-3)
Phenylethylamine (PEA) has been implicated in a number of central and peripheral nervous system disorders. Its possible mechanisms of action include stimulation via catecholamine release and direct stimulation by PEA. We have examined the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1a43945e10fc571acb1f244e6bf2cb
https://pubmed.ncbi.nlm.nih.gov/6247170
https://pubmed.ncbi.nlm.nih.gov/6247170
Autor:
Timothy R. Hansen, J. Alan Herd
Publikováno v:
Psychophysiology. 19(1)
Changes in blood pressure (BP) and heart rate (HR) were classically conditioned in squirrel monkeys using light as the conditional stimulus, and electric shock as the unconditional stimulus. The transient (lasting less than 5 min) and sustained (main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91e3240d384e6701a7834e3f656ca32
https://pubmed.ncbi.nlm.nih.gov/7058238
https://pubmed.ncbi.nlm.nih.gov/7058238
Autor:
Diwan Singh, Money C. Sutter, Dennis X. Dineen, Gordon L. Pullen, Timothy R. Hansen, Morley C. Sutter, William I. Rosenblum, Catherine C.Y. Pang, Farouk El-Sabban
Publikováno v:
Journal of Vascular Research. 17:328-329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c62efd05b355ed25fe4585f3a8d8b62
https://doi.org/10.1159/000158265
https://doi.org/10.1159/000158265
Publikováno v:
Psychophysiology; Nov1982, Vol. 19 Issue 6, following p718-722, 5p