Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Timothy R Hercus"'
Autor:
Timothy R Hercus, Emma F Barry, Mara Dottore, Barbara J McClure, Andrew I Webb, Angel F Lopez, Ian G Young, James M Murphy
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e74376 (2013)
Human interleukin-3 (hIL-3) is a polypeptide growth factor that regulates the proliferation, differentiation, survival and function of hematopoietic progenitors and many mature blood cell lineages. Although recombinant hIL-3 is a widely used laborato
Externí odkaz:
https://doaj.org/article/dfae7e17c9a84becbef847d834d58d54
Autor:
Winnie L. Kan, Urmi Dhagat, Kerstin B. Kaufmann, Timothy R. Hercus, Tracy L. Nero, Andy GX. Zeng, John Toubia, Emma F. Barry, Sophie E. Broughton, Guillermo A. Gomez, Brooks A. Benard, Mara Dottore, Karen S. Cheung Tung Shing, Helena Boutzen, Saumya E. Samaraweera, Kaylene J. Simpson, Liqing Jin, Gregory J. Goodall, C. Glenn Begley, Daniel Thomas, Paul G. Ekert, Denis Tvorogov, Richard J. D'Andrea, John E. Dick, Michael W. Parker, Angel F. Lopez
Publikováno v:
Cancer Discovery.
Leukemia stem cells (LSC) possess distinct self-renewal and arrested differentiation properties that are responsible for disease emergence, therapy failure and recurrence in acute myeloid leukemia (AML). Despite AML displaying extensive biological an
Autor:
Harshita Pant, Timothy R. Hercus, Damon J. Tumes, Kwok Ho Yip, Michael W. Parker, Catherine M. Owczarek, Angel F. Lopez, David P. Huston
Publikováno v:
The Journal of allergy and clinical immunology.
The family of cytokines that comprises IL-3, IL-5, and GM-CSF was discovered over 30 years ago, and their biological activities and resulting impact in clinical medicine has continued to expand ever since. Originally identified as bone marrow growth
Autor:
Hao Wang, Damon J. Tumes, Timothy R. Hercus, K. H. Yip, Christian Aloe, Ross Vlahos, Angel F. Lopez, Nick Wilson, Catherine M. Owczarek, Steven Bozinovski
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-11 (2022)
Acute respiratory distress syndrome (ARDS) is triggered by various aetiological factors such as trauma, sepsis and respiratory viruses including SARS-CoV-2 and influenza A virus. Immune profiling of severe COVID-19 patients has identified a complex p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffcb87256a417a89b6a60ee0103379d
https://hdl.handle.net/11541.2/30052
https://hdl.handle.net/11541.2/30052
Autor:
Gino Vairo, Nicholas J. Wilson, Hayley S. Ramshaw, Timo Kraushaar, Barbara J. McClure, Timothy R. Hercus, Mhairi Maxwell, Elmar Raquet, Damon J. Tumes, Duncan R. McKenzie, Kathleen Zeglinski, Harshita Pant, Michele A. Grimbaldeston, Catherine M. Owczarek, Joachim Röder, Angel F. Lopez, Jessica Chao, Kwok Ho Yip, Katherine Monaghan, Monther Alhamdoosh, Jia Hong Fong, Andrew Hammet
Allergic contact dermatitis (ACD) is a prevalent and poorly controlled inflammatory disease caused by skin infiltration of T cells and granulocytes. The beta common (βc) cytokines GM-CSF, IL-3, and IL-5 are powerful regulators of granulocyte functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66938273824c0ce03c6325a3d71da595
https://hdl.handle.net/11541.2/28703
https://hdl.handle.net/11541.2/28703
Autor:
Hao, Wang, Damon J, Tumes, Timothy R, Hercus, K H, Yip, Christian, Aloe, Ross, Vlahos, Angel F, Lopez, Nick, Wilson, Catherine M, Owczarek, Steven, Bozinovski
Publikováno v:
Cell deathdisease. 13(2)
Acute respiratory distress syndrome (ARDS) is triggered by various aetiological factors such as trauma, sepsis and respiratory viruses including SARS-CoV-2 and influenza A virus. Immune profiling of severe COVID-19 patients has identified a complex p
Autor:
Kwok Ho, Yip, Duncan, McKenzie, Hayley S, Ramshaw, Jessica, Chao, Barbara J, McClure, Elmar, Raquet, Timo, Kraushaar, Joachim, Röder, Mhairi, Maxwell, Monther, Alhamdoosh, Andrew, Hammet, Jia Hong, Fong, Kathleen, Zeglinski, Katherine, Monaghan, Harshita, Pant, Michele A, Grimbaldeston, Gino, Vairo, Nicholas J, Wilson, Catherine M, Owczarek, Timothy R, Hercus, Angel F, Lopez, Damon J, Tumes
Publikováno v:
The Journal of investigative dermatology. 142(4)
Allergic contact dermatitis (ACD) is a prevalent and poorly controlled inflammatory disease caused by skin infiltration of T cells and granulocytes. The beta common (β
Autor:
Gregory J. Goodall, Kaylene J. Simpson, Winnie L. Kan, Guillermo A. Gomez, John Toubia, Urmi Dhagat, Paul G Ekert, Daniel Thomas, Emma F Barry, Andy G.X. Zeng, Mara Dottore, Erwin M. Schoof, Denis Tvorogov, Sophie E. Broughton, C. Glenn Begley, Tracy L. Nero, Karen S. Cheung Tung Shing, Richard J D'Andrea, Kerstin B. Kaufmann, John E. Dick, Michael W. Parker, Timothy R. Hercus, Angel F. Lopez, Brooks Benard
Publikováno v:
SSRN Electronic Journal.
Leukemia stem cells (LSC) possess distinct self-renewal and arrested differentiation properties that are responsible for disease emergence, therapy failure and recurrence in acute myeloid leukemia (AML). Pleiotropic cytokines like interleukin (IL)-3
Autor:
Tracy L. Nero, Winnie L. Kan, Angel F. Lopez, Timothy R. Hercus, Karen S. Cheung Tung Shing, Denis Tvorogov, Michael W. Parker
Publikováno v:
Seminars in Immunology. 54:101513
Our understanding of the biological role of the βc family of cytokines has evolved enormously since their initial identification as bone marrow colony stimulating factors in the 1960′s. It has become abundantly clear over the intervening decades t
Autor:
Mara Dottore, Veronika Rayzman, Michael J. Wilson, Catherine M. Owczarek, Matthew P. Hardy, Timothy R. Hercus, Gino Vairo, Gail M. Gauvreau, Nicholas J. Wilson, Barbara J. McClure, Angel F. Lopez, Laura McMillan, Kirsten Edwards, Roma Sehmi, Steven G. Smith, Urmi Dhagat, Louis Fabri, Michael W. Parker, Hal Braley, Con Panousis, Andrew D. Nash
Publikováno v:
mAbs
The β common-signaling cytokines interleukin (IL)-3, granulocyte-macrophage colony stimulating factor (GM-CSF) and IL-5 stimulate pro-inflammatory activities of haematopoietic cells via a receptor complex incorporating cytokine-specific α and share