Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Timothy R H, Regnault"'
Autor:
Bryan S. Richardson, Akasham Rajagopaul, Barbra de Vrijer, Genevieve Eastabrook, Timothy R. H. Regnault
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-8 (2022)
Highlights Birth/placental wt is decreased in females as a measure of placental efficiency. Cord vein O2 is increased in females as a measure of placental O2 transport. Cord artery O2 is decreased in females as a measure of fetal systemic O2 levels.
Externí odkaz:
https://doaj.org/article/44ee80974cb94b7b916cc0c03466c931
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283118 (2023)
Pre-existing and gestationally-developed diabetes mellitus have been linked with impairments in placental villous trophoblast cell metabolic function, that are thought to underlie the development of metabolic diseases early in the lives of the expose
Externí odkaz:
https://doaj.org/article/abb3808fc5774427bb627ef594590fc5
Autor:
Zachary J. W. Easton, Ousseynou Sarr, Lin Zhao, Adriana Zardini Buzatto, Xian Luo, Shuang Zhao, Liang Li, Timothy R. H. Regnault
Publikováno v:
Metabolites, Vol 13, Iss 8, p 883 (2023)
Maternal obesity and gestational diabetes mellitus (GDM) are linked with impaired placental function and early onset of non-communicable cardiometabolic diseases in offspring. Previous studies have highlighted that the dietary non-esterified fatty ac
Externí odkaz:
https://doaj.org/article/e3675e938dbb457089ab49434ec1ac09
Autor:
Alexander L. Pendleton, Stephanie R. Wesolowski, Timothy R. H. Regnault, Ronald M. Lynch, Sean W. Limesand
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Intrauterine growth restriction (IUGR) of the fetus, resulting from placental insufficiency (PI), is characterized by low fetal oxygen and nutrient concentrations that stunt growth rates of metabolic organs. Numerous animal models of IUGR recapitulat
Externí odkaz:
https://doaj.org/article/fb182e110b44438d8eb08377868b43c6
Autor:
Rebecca L. Wilson, Kristin Lampe, Brad J. Matushewski, Timothy R. H. Regnault, Helen N. Jones
Publikováno v:
Methods and Protocols, Vol 4, Iss 3, p 58 (2021)
One of the greatest challenges to the development and implementation of pregnancy therapeutics is the ability to rigorously test treatments in clinically relevant animal models. Guinea pigs offer a unique advantage in studying the placenta, fetal dev
Externí odkaz:
https://doaj.org/article/f452bdcc82c94432949b49166685b98e
Autor:
Kevin J Sinclair, Lanette J Friesen-Waldner, Colin M McCurdy, Curtis N Wiens, Trevor P Wade, Barbra de Vrijer, Timothy R H Regnault, Charles A McKenzie
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192900 (2018)
To examine the feasibility of using MRI to identify differences in liver size and fat deposition in fetal guinea pigs exposed to an in utero environment influenced by maternal consumption of a Western diet.Female guinea pigs fed either an energy-dens
Externí odkaz:
https://doaj.org/article/8a020e581cb04574b20cc0068e0ba190
Autor:
Lanette J. Friesen-Waldner, Katherine E. Mathers, Timothy R. H. Regnault, Neetin H Prabhu, Charles A. McKenzie, Kevin J. Sinclair, Conrad B Pitts, Trevor Wade, Leigh K. Smith
Publikováno v:
Journal of Magnetic Resonance Imaging. 54:1404-1414
Background Alterations in glycolysis are central to the increasing incidence of non-alcoholic fatty liver disease (NAFLD), highlighting a need for in vivo, non-invasive technologies to understand the development of hepatic metabolic aberrations. Purp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d7391e53fa04690c02a403272235c81
https://doi.org/10.1002/jmri.27677
https://doi.org/10.1002/jmri.27677
Autor:
Alison V. Lee, Lan You, Se-Young Oh, Ziwei Li, Alexandra Code, Cuilan Zhu, Rebecca E. Fisher-Heffernan, Timothy R. H. Regnault, Cornelis F. M. De Lange, Lee-Anne Huber, Niel A. Karrow
Publikováno v:
Animals, Vol 9, Iss 3, p 80 (2019)
Weaning stress can negatively impact a pig’s performance; dietary supplementation with omega-3 polyunsaturated fatty acids (n-3 PUFA) reduces inflammatory stress and promotes nursery pig’s health and growth. Fish oil (FO) is a major source of n-3
Externí odkaz:
https://doaj.org/article/2728005abd4b4e2f8d67e6faef690700
Autor:
Christina Vanderboor, Zachary J. W. Easton, Flavien Delhaes, Timothy R. H. Regnault, Lin Zhao, Katherine E. Mathers
Publikováno v:
Reproduction
Paediatrics Publications
Paediatrics Publications
Placental villous trophoblast mitochondrial respiratory function is critical for a successful pregnancy and environmental influences such as maternal obesity have been associated with respiratory impairment at term. More recently, a gestational high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30e6bb6f9c80682e046e61e070aa01b
https://doi.org/10.1530/rep-19-0433
https://doi.org/10.1530/rep-19-0433
Autor:
Erin Vanessa LaRae Smith, Rebecca Maree Dyson, Christina M. G. Vanderboor, Ousseynou Sarr, Jane Anderson, Mary J. Berry, Timothy R. H. Regnault, Lifeng Peng, Clint Gray
Publikováno v:
Paediatrics Publications
International Journal of Molecular Sciences, Vol 23, Iss 999, p 999 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 999
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 999, p 999 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 999
International Journal of Molecular Sciences
Excess dietary fructose is a major public health concern, yet little is known about its influence on offspring development and later-life disease when consumed in excess during pregnancy. To determine whether increased maternal fructose intake could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1e700d9c53bd10de0fbf2ad6c36455
https://ir.lib.uwo.ca/paedpub/2175
https://ir.lib.uwo.ca/paedpub/2175
