Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Timothy R Crother"'
Autor:
Joseph H Skalski, Jose J Limon, Purnima Sharma, Matthew D Gargus, Christopher Nguyen, Jie Tang, Ana Lucia Coelho, Cory M Hogaboam, Timothy R Crother, David M Underhill
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007260 (2018)
The gastrointestinal microbiota influences immune function throughout the body. The gut-lung axis refers to the concept that alterations of gut commensal microorganisms can have a distant effect on immune function in the lung. Overgrowth of intestina
Externí odkaz:
https://doaj.org/article/e6aae19f21424909888ee5b9ea8db2f6
Autor:
Heather D Jones, Jeena Yoo, Timothy R Crother, Pierre Kyme, Anat Ben-Shlomo, Ramtin Khalafi, Ching W Tseng, William C Parks, Moshe Arditi, George Y Liu, Kenichi Shimada
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128735 (2015)
Externí odkaz:
https://doaj.org/article/c5970b111dff402f846a3d594bf3c19a
Autor:
Heather D Jones, Jeena Yoo, Timothy R Crother, Pierre Kyme, Anat Ben-Shlomo, Ramtin Khalafi, Ching W Tseng, William C Parks, Moshe Arditi, George Y Liu, Kenichi Shimada
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123460 (2015)
BACKGROUND:Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransferase is an enzyme that is highly upregul
Externí odkaz:
https://doaj.org/article/840aa11d64a1475e8137267350b4f78c
Autor:
Ana Paula Lombardi Pereira, Emily Aubuchon, Debbie P. Moreira, Malcolm Lane, Thacyana T. Carvalho, Thassio R. R. Mesquita, Youngho Lee, Timothy R. Crother, Rebecca A. Porritt, Waldiceu A. Verri, Magali Noval Rivas, Moshe Arditi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundKawasaki disease (KD), an acute febrile illness and systemic vasculitis, is the leading cause of acquired heart disease in children in industrialized countries. KD leads to the development of coronary artery aneurysms (CAA) in affected chil
Externí odkaz:
https://doaj.org/article/bab04e8fb821462888b2d774045c3cc8
Autor:
Madhulika Jupelli, Kenichi Shimada, Norika Chiba, Anatoly Slepenkin, Randa Alsabeh, Heather D Jones, Ellena Peterson, Shuang Chen, Moshe Arditi, Timothy R Crother
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77447 (2013)
Chlamydia pneumoniae (CP) lung infection can induce chronic lung inflammation and is associated with not only acute asthma but also COPD exacerbations. However, in mouse models of CP infection, most studies have investigated specifically the acute ph
Externí odkaz:
https://doaj.org/article/57fb2d28ecfb4ec4a9f3d685dfce98b5
Autor:
Timothy R Crother, Jun Ma, Madhulika Jupelli, Norika Chiba, Shuang Chen, Anatoly Slepenkin, Randa Alsabeh, Ellena Peterson, Kenichi Shimada, Moshe Arditi
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48655 (2012)
Plasmacytoid dendritic cells (pDCs) are known for their robust antiviral response and their pro-tolerance effects towards allergic diseases and tissue engraftments. However, little is known about the role pDCs may play during a bacterial infection, i
Externí odkaz:
https://doaj.org/article/f1abb9359f904d489f54f50175e898d3
Autor:
Kenichi Shimada, Timothy R Crother, Justin Karlin, Shuang Chen, Norika Chiba, V Krishnan Ramanujan, Laurent Vergnes, David M Ojcius, Moshe Arditi
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21477 (2011)
Chlamydia pneumoniae (CP) is an important human pathogen that causes atypical pneumonia and is associated with various chronic inflammatory disorders. Caspase-1 is a key component of the 'inflammasome', and is required to cleave pro-IL-1β to bioacti
Externí odkaz:
https://doaj.org/article/c49c1749eb40487a9cddb68386c87d69
Autor:
Timothy R Crother, Nicolas W J Schröder, Justin Karlin, Shuang Chen, Kenichi Shimada, Anatoly Slepenkin, Randa Alsabeh, Ellena Peterson, Moshe Arditi
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20784 (2011)
Chlamydia pneumoniae (CP) is associated with induction and exacerbation of asthma. CP infection can induce allergic airway sensitization in mice in a dose- and time-dependent manner. Allergen exposure 5 days after a low dose (mild-moderate), but not
Externí odkaz:
https://doaj.org/article/4d3a02221b8a4ee982f053fe32c90b7c
Autor:
Antoine Soliman, Kathrin S Michelsen, Hisae Karahashi, Jing Lu, Fan Jing Meng, Xiaowu Qu, Timothy R Crother, Shervin Rabizadeh, Shuang Chen, Michael S Caplan, Moshe Arditi, Tamas Jilling
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e15044 (2010)
Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in neonatal intensive care units, however its pathogenesis is not completely understood. We have previously shown that platelet activating factor (PAF), bacteria and TLR4 a
Externí odkaz:
https://doaj.org/article/573ab98df4cf421aab6794e1af1f1015
Autor:
Emily L Lowe, Timothy R Crother, Shervin Rabizadeh, Bing Hu, Hanlin Wang, Shuang Chen, Kenichi Shimada, Michelle H Wong, Kathrin S Michelsen, Moshe Arditi
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13027 (2010)
Inflammatory bowel disease (IBD) is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but thought to result from a dysregulated adaptive and innate immune response to microbial produ
Externí odkaz:
https://doaj.org/article/28f8754bfb5e459b99e01e9d19755389