Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Timothy Q. Vu"'
Autor:
Justin A. Peruzzi, Jan Steinkühler, Timothy Q. Vu, Taylor F. Gunnels, Vivian T. Hu, Peilong Lu, David Baker, Neha P. Kamat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The organization of membrane proteins between and within membrane-bound compartments is critical to cellular function. Yet we lack approaches to regulate this organization in a range of membrane-based materials, such as engineered cells, exo
Externí odkaz:
https://doaj.org/article/dd904c5a265f4a8588ba54371b068b97
Publikováno v:
Biomacromolecules. 24:1574-1584
Publikováno v:
Small Methods.
Publikováno v:
Trends in Biotechnology. 41:276-277
The addition of both cell-targeting moieties and polyethylene glycol (PEG) to nanoparticle (NP) drug delivery systems is a standard approach to improve the biodistribution, specificity, and uptake of therapeutic cargo. The spatial presentation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec07d45488b03392b6711fe2db78b89
https://doi.org/10.1101/2022.10.18.512758
https://doi.org/10.1101/2022.10.18.512758
Autor:
Justin A. Peruzzi, Jan Steinkühler, Timothy Q. Vu, Taylor F. Gunnels, Peilong Lu, David Baker, Neha P. Kamat
The extent to which membrane biophysical properties, such as hydrophobic thickness, can drive membrane protein organization remains unknown. Inspired by this question, we used de novo protein design, molecular dynamic simulations, and cell-free syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef526797ae74491ed93bbc179a39d029
https://doi.org/10.1101/2022.06.01.494374
https://doi.org/10.1101/2022.06.01.494374
Publikováno v:
Nano Lett
Ligand spatial presentation and density play important roles in signaling pathways mediated by cell receptors and are critical parameters when designing protein-conjugated therapeutic nanoparticles. Here, we harness lipid phase separation to spatiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09c4fc52eb105d3efccee49dd1d6d58
https://europepmc.org/articles/PMC9680886/
https://europepmc.org/articles/PMC9680886/
Publikováno v:
Angew Chem Int Ed Engl
Targeted vesicle fusion is a promising approach to selectively control interactions between vesicle compartments and would enable the initiation of biological reactions in complex aqueous environments. Here, we explore how two features of vesicle mem
Targeted vesicle fusion is a promising approach to selectively control interactions between vesicle compartments and would enable the initiation of biological reactions in complex aqueous environments. Here, we explore how two features of vesicle mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f56e9d91ce3392593677a167cb3319
Autor:
Huiyi H. Chang, Kari L. Christe, Una Lee, Timothy Q. Vu, Leif A. Havton, Victor Pikov, Jaime H. Nieto
Publikováno v:
Chang, HH; Lee, UJ; Vu, T; Pikov, V; Nieto, JH; Christe, KL; et al.(2018). EMG Characteristics of the External Anal Sphincter Guarding Reflex and Effects of a Unilateral Ventral Root Avulsion Injury in Rhesus Macaques (Macaca mulatta).. Journal of neurophysiology. doi: 10.1152/jn.00435.2017. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3pd417d0
The external anal sphincter (EAS) is important for the maintenance of bowel continence and may be compromised by a variety of neuropathic conditions. However, large animal models for the study of EAS functions have been sparse. The EAS guarding refle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bd4e33287eaac501be9ae8e276d1b6
http://www.escholarship.org/uc/item/3pd417d0
http://www.escholarship.org/uc/item/3pd417d0