Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Timothy Phoenix"'
Autor:
Rachid Drissi, Maryam Fouladi, Mariko DeWire, Charles B. Stevenson, Christine Fuller, Lisa Dyer, Timothy Phoenix, Deepak Kumar Mishra, Xiaoting Zhu, Satarupa Sengupta, Shiva Senthil Kumar
Histone mutation and BMI-1 expression (log2 fold change) of patient tumor section used for IHC in figure S1A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbffd99d21e0bc62b75460bd78e0565
https://doi.org/10.1158/1541-7786.22515654.v1
https://doi.org/10.1158/1541-7786.22515654.v1
Autor:
Rachid Drissi, Maryam Fouladi, Mariko DeWire, Charles B. Stevenson, Christine Fuller, Lisa Dyer, Timothy Phoenix, Deepak Kumar Mishra, Xiaoting Zhu, Satarupa Sengupta, Shiva Senthil Kumar
Survival probability of mice post-drug withdrawal starting from drug holiday. P values are indicated, *p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5206fee724bb32e1cb86e254b9769f0c
https://doi.org/10.1158/1541-7786.22515660
https://doi.org/10.1158/1541-7786.22515660
Autor:
Rachid Drissi, Maryam Fouladi, Mariko DeWire, Charles B. Stevenson, Christine Fuller, Lisa Dyer, Timothy Phoenix, Deepak Kumar Mishra, Xiaoting Zhu, Satarupa Sengupta, Shiva Senthil Kumar
B, CCHMC-DIPG-1 cells treated with PTC596 (100 nM) were quantified for the number of γH2AX foci/cell at the indicated time points. C, Representative IF images and cell cycle analysis (with the indicated % of cells) of CCHMC-DIPG-2 cells treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c6cb02bcc585707227db7019a61fa0
https://doi.org/10.1158/1541-7786.22515675
https://doi.org/10.1158/1541-7786.22515675
Autor:
Rachid Drissi, Maryam Fouladi, Mariko DeWire, Charles B. Stevenson, Christine Fuller, Lisa Dyer, Timothy Phoenix, Deepak Kumar Mishra, Xiaoting Zhu, Satarupa Sengupta, Shiva Senthil Kumar
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47449a39b69f0805caa2b66ca5da0b5e
https://doi.org/10.1158/1541-7786.22515657
https://doi.org/10.1158/1541-7786.22515657
Autor:
Rachid Drissi, Maryam Fouladi, Mariko DeWire, Charles B. Stevenson, Christine Fuller, Lisa Dyer, Timothy Phoenix, Deepak Kumar Mishra, Xiaoting Zhu, Satarupa Sengupta, Shiva Senthil Kumar
A, Scheme representing the experiment design of PTC596 treatment, drug wash-off and time points to evaluate PTC596 activity by immunoblot analysis of BMI-1, H2AK119Ub (Day 4) and cell growth by WST-1 assay (Days 8 and 11) in HFF, CCHMC-DIPG-1 and CCH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b24383d282b708bf3f52c545123fa5
https://doi.org/10.1158/1541-7786.22515678
https://doi.org/10.1158/1541-7786.22515678
Autor:
Rachid Drissi, Maryam Fouladi, Mariko DeWire, Charles B. Stevenson, Christine Fuller, Lisa Dyer, Timothy Phoenix, Deepak Kumar Mishra, Xiaoting Zhu, Satarupa Sengupta, Shiva Senthil Kumar
Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis pediatric brain tumor with a median survival of less than 1 year. No effective therapy is currently available, and no therapeutic advances have been made in several decades. We have previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aab275061c6ea6d5cd7b916bbb127f1
https://doi.org/10.1158/1541-7786.c.6541155
https://doi.org/10.1158/1541-7786.c.6541155
Autor:
Aniruddha Karve, Janki Desai, Nimita Dave, Timothy Phoenix, Gary Gudelsky, David Plas, Biplab Dasgupta, Trisha Wise-Draper, Pankaj Desai
Publikováno v:
Neuro-Oncology. 24:vii233-vii233
PURPOSE Despite significant advances in multimodal approaches for the treatment of glioblastoma (GBM), the outcome for the patients remains dismal. Previous research from our lab has shown that aromatase (CYP19A1), an enzyme that catalyzes in situ pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b098dfc0e51f9172106c4b00e66bf8
https://doi.org/10.1093/neuonc/noac209.899
https://doi.org/10.1093/neuonc/noac209.899
Autor:
Leslie Lupien, Veronica Rendo, Eric Morin, Nicholas Khuu, Jeromy DiGiacomo, Prasidda Khadka, Madison Chacon, Sophie Lu, Kristine Pelton, Lara Elcavage, Jaldeep Langhnoja, Keith Ligon, Rameen Beroukhim, Timothy Phoenix, Pratiti Bandopadhayay
Publikováno v:
Neuro-Oncology. 24:i31-i31
TP53 is the most frequently mutated tumor suppressor with somatic alterations found in approximately 50% of all human cancers. In the remaining TP53 wild-type (WT) tumors, functional inactivation of the p53 pathway may be achieved through a variety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09d35f117b0a17b5cb7c195f2c549ce5
https://doi.org/10.1093/neuonc/noac079.111
https://doi.org/10.1093/neuonc/noac079.111
Autor:
Carl Koschmann, Abed Rahman Kawakibi, Rohinton Tarapore, Sharon Gardner, Chase Thomas, Rodrigo Cartaxo, Viveka Yadav, Andrew Chi, Sylvia Kurz, Patrick Wen, Isabel Arrillaga, Tracy Batchelor, Nicholas Butowski, Ashley Sumrall, Nicole Shonka, Rebecca Harrison, John De Groot, Minesh Mehta, Yazmin Odia, Matthew Hall, Doured Daghistani, Timothy Cloughesy, Benjamin Ellingson, Michelle Kim, Yoshie Umemura, Hugh Garton, Andrea Franson, Patricia Robertson, Jonathan Schwartz, Bernard Marini, Manjunath Pai, Timothy Phoenix, Sunjong Ji, Evan Cantor, Zachary Miklja, Brendan Mullan, Amy Bruzek, Ruby Siada, Jessica Cummings, Stefanie Stallard, Kyle Wierzbicki, Alyssa Paul, Ian Wolfe, Matthew Dun, Jason Cain, Li Jiang, Mariella Filbin, Pankaj Vats, Chandan Kumar-Sinha, Rajen Mody, Arul Chinnaiyan, Drew Pratt, Sriram Venneti, Guangrong Lu, Sabine Mueller, Adam Resnick, Javad Nazarian, Sebastian Waszak, Joshua Allen
Patients with diffuse midline glioma (DMG) harboring H3 K27M mutation have no proven therapies beyond radiation. ONC201, a DRD2 antagonist and mitochondrial ClpP agonist, has induced early responses in patients with H3 K27M-mutant DMG. We performed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f1acf7b9e4e63c9e411b7056b9a949
https://doi.org/10.21203/rs.3.rs-69706/v1
https://doi.org/10.21203/rs.3.rs-69706/v1
Diffuse intrinsic pontine glioma (DIPG) is a universally fatal pediatric cancer arising in the brainstem of children. Their unique brainstem location and pathology, including limited disruption of the blood-brain barrier (BBB), present a significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28468eb4829da418f7277c6f75c09d5
https://europepmc.org/articles/PMC6012541/
https://europepmc.org/articles/PMC6012541/