Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Timothy P. Coogan"'
Publikováno v:
International journal of toxicology. 38(3)
Fulranumab, an anti-human nerve growth factor antibody, was evaluated in a series of nonclinical toxicology studies. No treatment effects were observed in adolescent cynomolgus monkeys in standard design, repeat-dose toxicology studies of up to 6 mon
Autor:
Ling Lin, Chaozhong Cai, Christopher M. Flores, Timothy P Coogan, Edmund K. LeGrand, Ellen E. Codd, Raymond W. Colburn, Angelique Leone, Charles Y. Wang, Mcdonnell Mark E, Scott L. Dax, Michael R. Brandt, Stewart Bryant, Bart DeCorte, James J. McNally, John R. Mabus, Sui-Po Zhang, John R. Carson, Michael Kemmerer, Dennis J. Stone, James M Lenhard, Michael K. McMillian, Kristen M. Chevalier, Judith Baker
Publikováno v:
Toxicological Sciences. 117:493-504
The unexpected observation of a hyperglycemic effect of some tricycle-based delta opioid receptor (DOR) agonists led to a series of studies to better understand the finding. Single administration of two novel tricyclic DOR agonists dose dependently e
Autor:
Paul Barrow, Kathryn Bayne, Joerg Bluemel, Frank Brennan, Iris D. Bolton, Christopher J. Bowman, Wayne R. Buck, Leigh Ann Burns-Naas, David B. Burr, Jennifer A. Cann, Annick J. Cauvin, Joy A. Cavagnaro, Ulrich Certa, Kathryn Chapman, Gary J. Chellman, Timothy P. Coogan, Jessica Couch, Lolke de Haan, Thierry Decelle, Annie Delaunois, Raffaella Faggioni, Betsy Ferguson, John Finch, Virginia Fisher, Werner Frings, Thomas Gelzleichter, Andreas Gschwind, Robert Hall, Wendy G. Halpern, Tobias Heckel, Kristin L. Henson, Susan Henwood, Jonathan R. Heyen, William Oliver Iverson, Mary Jeanne Kallman, Joachim Kaspareit, Tina Koban, Sven Korte, Pierre Lainée, Michael W. Leach, Lynne LeSauteur, Anne D. Lewis, Beatriz Silva Lima, Yanfei L. Ma, Keith G. Mansfield, C. Marc Luetjens, Pauline L. Martin, Kerstin Mätz-Rensing, Lars Fris Mikkelsen, Barbara Mounho-Zamora, Wolfgang Müller, Dennis J. Murphy, Marc Niehoff, Birgit Niggemann, Helen Palmer, Daniel J. Patrick, Christopher Peters, Marie-Soleil Piché, Mark Prescott, Kamm Prongay, Marlon C. Rebelatto, Alexandre Reymond, Laura Richman, Christian Roos, Lorin K. Roskos, Chandrassegar Saravanan, Vito G. Sasseville, Emanuel Schenck, Georg Schmitt, Jacintha M. Shenton, Anjali Singh, Matthew Skinner, David Glenn Smith, Markus Stephan-Gueldner, Marque Todd, Chih-Ming L. Tseng, John L. Vahle, Jean-Pierre Valentin, Hugo M. Vargas, Eric Wakshull, Lutz Walter, Gerhard F. Weinbauer, Joachim Wistuba, Harry Yang, Dietmar Zinner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc7e40da8c9c9a862d5e68f270d49f3
https://doi.org/10.1016/b978-0-12-417144-2.09993-5
https://doi.org/10.1016/b978-0-12-417144-2.09993-5
Autor:
Timothy P. Coogan, Pauline L. Martin
Nonclinical juvenile toxicity studies may need to be considered to support the use of pharmaceuticals in pediatric patients. If needed, they are generally conducted in rodents; nonhuman primates (NHPs) are used infrequently. At birth, NHPs are more d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f47fa212448b9418398662b1796a56e
https://doi.org/10.1016/b978-0-12-417144-2.00026-3
https://doi.org/10.1016/b978-0-12-417144-2.00026-3
Determination of the adsorption of tramadol hydrochloride by activated charcoal in vitro and in vivo
Autor:
Robert B. Raffa, Chunyu Wu, Dennis J. Stone, Michael R. Borenstein, Timothy P Coogan, Ellen E. Codd
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 43:205-210
Although tramadol is one of the most widely used centrally acting analgesics worldwide, no literature is available regarding adsorption of tramadol HCl powder or tablets (Ultram; 50 mg tramadol HCl per tablet) by activated charcoal (AC) for use as po
Autor:
Noriyuki Shirais, Timothy P. Coogan
Publikováno v:
Toxic Substance Mechanisms. 16:357-370
Publikováno v:
Pediatric Drug Development,2nd Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3747a5ee1475d858189e8264a58e1c0
https://doi.org/10.1002/9781118312087.ch18
https://doi.org/10.1002/9781118312087.ch18
Publikováno v:
Pediatric Drug Development: Concepts and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::139cfd5e97fe59fe39afd5d2f8f1bc44
https://doi.org/10.1002/9781118312087.ch19
https://doi.org/10.1002/9781118312087.ch19
Publikováno v:
Pediatric Nonclinical Drug Testing: Principles, Requirements, and Practices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8aaae3c696db02f4a7d1471038cee64
https://doi.org/10.1002/9781118168226.ch8
https://doi.org/10.1002/9781118168226.ch8