Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Timothy P. Burns"'
Autor:
Suet Kee Loo, Gabriel Sica, Xian Wang, Tingting Li, Luping Chen, Autumn Gaither-Davis, Yufei Huang, Timothy F. Burns, Laura P. Stabile, Shou-Jiang Gao
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background Lung cancer, a leading global cause of cancer-related mortality, necessitates enhanced prognostic markers for improved treatment outcomes. We have previously shown a tumor suppressive role of cytosolic arginine sensor for mTORC1 s
Externí odkaz:
https://doaj.org/article/acd6b3c9b3c7486ca1dd6bfc35c3d602
Autor:
Rajendra P. Gajula, Sivarajan T. Chettiar, Russell D. Williams, Katriana Nugent, Yoshinori Kato, Hailun Wang, Reem Malek, Kekoa Taparra, Jessica Cades, Anvesh Annadanam, A-Rum Yoon, Elana Fertig, Beth A. Firulli, Lucia Mazzacurati, Timothy F. Burns, Anthony B. Firulli, Steven S. An, Phuoc T. Tran
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 57, Iss , Pp 101010- (2024)
Externí odkaz:
https://doaj.org/article/b493658f8b604dd9813e1e3c4f3fd4e0
Autor:
Abdulkader Yassin-Kassab, Suman Chatterjee, Nayel Khan, Nathaniel Wang, Vlad C. Sandulache, Eric H-B. Huang, Timothy F. Burns, Umamaheswar Duvvuri
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Head and neck squamous cell carcinoma (HNSCC) constitutes one of the most common types of human cancers and often metastasizes to lymph nodes. Platinum-based chemotherapeutic drugs are commonly used for treatment of a wide range of cancers,
Externí odkaz:
https://doaj.org/article/51729d77fd4f4e76a3435a6037e5e191
Autor:
Jaime L. Schneider, Khvaramze Shaverdashvili, Mari Mino-Kenudson, Subba R. Digumarthy, Andrew Do, Audrey Liu, Justin F. Gainor, Jochen K. Lennerz, Timothy F. Burns, Jessica J. Lin
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Acquired drug resistance remains a major problem across oncogene-addicted cancers. Elucidation of mechanisms of resistance can inform rational treatment strategies for patients relapsing on targeted therapies while offering insights into tum
Externí odkaz:
https://doaj.org/article/39fd463012fa4aa7af342003242f7782
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The influence of sex and body mass index (BMI) on the efficacy of immune checkpoint inhibitors (ICIs) in advanced non-small cell lung cancer (NSCLC) patients remains unclear. We conducted a retrospective study to evaluate the relationship be
Externí odkaz:
https://doaj.org/article/72939d3e536647c1b974a8e9d72c5507
Autor:
Muhammad Naeem Anwar, Timothy J. Burns
Publikováno v:
Physics Letters B, Vol 847, Iss , Pp 138248- (2023)
We present new linear relations among the masses of S-wave tetraquarks with either one flavour (QQQ¯Q¯) or two (QQq¯q¯). Because the relations are sensitive to the hidden-colour, spin, and spatial degrees of freedom, comparison to experimental da
Externí odkaz:
https://doaj.org/article/9e68741d05f14b43bd9d43cee8540041
Autor:
Laura P. Stabile, Vinod Kumar, Autumn Gaither-Davis, Eric H. Huang, Frank P. Vendetti, Princey Devadassan, Sanja Dacic, Riyue Bao, Richard A. Steinman, Timothy F. Burns, Christopher J. Bakkenist
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Human lung adenocarcinoma (LUAD) in current or former smokers exhibits a high tumor mutational burden (TMB) and distinct mutational signatures. Syngeneic mouse models of clinically relevant smoking-related LUAD are lacking. We established and charact
Externí odkaz:
https://doaj.org/article/1954918282e2448aad0dedcd45e8477d
Autor:
Ashwin Somasundaram, Timothy F. Burns
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Lung cancer is the deadliest malignancy with more cancer deaths per year than the next three cancers combined. Despite remarkable advances in targeted therapy, advanced lung cancer patients have not experienced a significant improvement in m
Externí odkaz:
https://doaj.org/article/655237baa0244030bc3dd2531481c610
Autor:
Anthony R. Mato, Meghan Thompson, John N. Allan, Danielle M. Brander, John M. Pagel, Chaitra S. Ujjani, Brian T. Hill, Nicole Lamanna, Frederick Lansigan, Ryan Jacobs, Mazyar Shadman, Alan P. Skarbnik, Jeffrey J. Pu, Paul M. Barr, Alison R. Sehgal, Bruce D. Cheson, Clive S. Zent, Hande H. Tuncer, Stephen J. Schuster, Peter V. Pickens, Nirav N. Shah, Andre Goy, Allison M. Winter, Christine Garcia, Kaitlin Kennard, Krista Isaac, Colleen Dorsey, Lisa M. Gashonia, Arun K. Singavi, Lindsey E. Roeker, Andrew Zelenetz, Annalynn Williams, Christina Howlett, Hanna Weissbrot, Naveed Ali, Sirin Khajavian, Andrea Sitlinger, Eve Tranchito, Joanna Rhodes, Joshua Felsenfeld, Neil Bailey, Bhavisha Patel, Timothy F. Burns, Melissa Yacur, Mansi Malhotra, Jakub Svoboda, Richard R. Furman, Chadi Nabhan
Publikováno v:
Haematologica, Vol 103, Iss 9 (2018)
Venetoclax is a BCL2 inhibitor approved for 17p-deleted relapsed/refractory chronic lymphocytic leukemia with activity following kinase inhibitors. We conducted a multicenter retrospective cohort analysis of patients with chronic lymphocytic leukemia
Externí odkaz:
https://doaj.org/article/cf0cc2d2d3144e71a74d686f011301aa
Autor:
Rajendra P. Gajula, Sivarajan T. Chettiar, Russell D. Williams, Katriana Nugent, Yoshinori Kato, Hailun Wang, Reem Malek, Kekoa Taparra, Jessica Cades, Anvesh Annadanam, A-Rum Yoon, Elana Fertig, Beth A. Firulli, Lucia Mazzacurati, Timothy F. Burns, Anthony B. Firulli, Steven S. An, Phuoc T. Tran
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 1, Pp 16-31 (2015)
The TWIST1 gene has diverse roles in development and pathologic diseases such as cancer. TWIST1 is a dimeric basic helix-loop-helix (bHLH) transcription factor existing as TWIST1-TWIST1 or TWIST1-E12/47. TWIST1 partner choice and DNA binding can be i
Externí odkaz:
https://doaj.org/article/98b9b6cdc1dd40f8827a215c79bd3b7e