Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Timothy P Padera"'
Autor:
Lance L Munn, Mohammad R Nikmaneshi, Laurel B Darragh, Sana D Karam, Pinji Lei, Hengbo Zhou, Meghan J O’Melia, James W Baish, Lutz Menzel, Johanna J Rajotte, Mohammad S Razavi Rizi, Matthew G Vander Heiden, Timothy P Padera
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c6e1acbf087946179d227bb69b62a486
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 12, p e1005231 (2016)
The lymphatic system is responsible for transporting interstitial fluid back to the bloodstream, but unlike the cardiovascular system, lacks a centralized pump-the heart-to drive flow. Instead, each collecting lymphatic vessel can individually contra
Externí odkaz:
https://doaj.org/article/4f9e4bf15dc64065b63b37dc112b6ee1
Autor:
Nicola C. Frenkel, Susanna Poghosyan, André Verheem, Timothy P. Padera, Inne H. M. Borel Rinkes, Onno Kranenburg, Jeroen Hagendoorn
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract The liver’s cellular functions are sustained by a hierarchical, segmentally-organized vascular system. Additionally, liver lymphatic vessels are thought to drain to perihepatic lymph nodes. Surprisingly, while recent findings highlight the
Externí odkaz:
https://doaj.org/article/83a9268bbc9c4e1cb850f89e226f267c
Autor:
John D. Martin, Ryan M. Lanning, Vikash P. Chauhan, Margaret R. Martin, Ahmed S. Mousa, Walid S. Kamoun, Hee-Sun Han, Hang Lee, Triantafyllos Stylianopoulos, Moungi G. Bawendi, Dan G. Duda, Edward B. Brown, Timothy P. Padera, Dai Fukumura, Rakesh K. Jain
Publikováno v:
Clinical Cancer Research. 28:3076-3090
Purpose: The abnormal function of tumor blood vessels causes tissue hypoxia, promoting disease progression and treatment resistance. Although tumor microenvironment normalization strategies can alleviate hypoxia globally, how local oxygen levels chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4a5363475591f35309b16beae72815
https://doi.org/10.1158/1078-0432.ccr-22-0486
https://doi.org/10.1158/1078-0432.ccr-22-0486
Autor:
Rakesh K. Jain, Dai Fukumura, Kevin R. Kozak, Jennifer Lobo, Shan Liao, Tohru Hoshida, Angera H. Kuo, Timothy P. Padera
Blood vessels are required for a tumor to grow and functional lymphatic vessels are required for it to disseminate to lymph nodes. In an attempt to eradicate both the primary tumor and its lymphatic metastasis, we targeted both blood and lymphatic ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c8b163b2a7acad36aef29676556a6f
https://doi.org/10.1158/1535-7163.c.6531720.v1
https://doi.org/10.1158/1535-7163.c.6531720.v1
Autor:
Dai Fukumura, Rakesh K. Jain, Satoshi Kashiwagi, Gregory Nelson, Tohru Hoshida, Timothy P. Padera, Jeroen Hagendoorn, Johanna Lahdenranta
Lymphatic metastasis is a critical determinant of cancer prognosis. Recently, several lymphangiogenic molecules such as vascular endothelial growth factor (VEGF)-C and VEGF-D were identified. However, the mechanistic understanding of lymphatic metast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc39dc41d170a4d5e502e16000ff8ddc
https://doi.org/10.1158/0008-5472.c.6499860.v1
https://doi.org/10.1158/0008-5472.c.6499860.v1
Autor:
Dai Fukumura, Rakesh K. Jain, Satoshi Kashiwagi, Gregory Nelson, Tohru Hoshida, Timothy P. Padera, Jeroen Hagendoorn, Johanna Lahdenranta
Supplementary Figure Legend from Endothelial Nitric Oxide Synthase Mediates Lymphangiogenesis and Lymphatic Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fbd9c71376669d64dc4e099e148ecc
https://doi.org/10.1158/0008-5472.22381416.v1
https://doi.org/10.1158/0008-5472.22381416.v1
Autor:
Dai Fukumura, Rakesh K. Jain, Satoshi Kashiwagi, Gregory Nelson, Tohru Hoshida, Timothy P. Padera, Jeroen Hagendoorn, Johanna Lahdenranta
Supplementary Figure 1 from Endothelial Nitric Oxide Synthase Mediates Lymphangiogenesis and Lymphatic Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0b0af60c94e593257d8c0766e3ca13
https://doi.org/10.1158/0008-5472.22381419.v1
https://doi.org/10.1158/0008-5472.22381419.v1
Publikováno v:
Cells, Vol 10, Iss 3, p 627 (2021)
Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate. Thus, it is important to understand the mechanisms by which
Externí odkaz:
https://doaj.org/article/14a835ac59d5464bbe107fe82ee5d35a
Autor:
Dhruv Singhal, Katy Börner, Elliot L. Chaikof, Michael Detmar, Maija Hollmén, Jeffrey J. Iliff, Maxim Itkin, Taija Makinen, Guillermo Oliver, Timothy P. Padera, Ellen M. Quardokus, Andrea J. Radtke, Hiroo Suami, Griffin M. Weber, Ilsa I. Rovira, Selen C. Muratoglu, Zorina S. Galis
Publikováno v:
Frontiers in Physiology, 14
Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the body and contributes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272ec1adcbd2c962910b68c0a237080e
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-499027
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-499027