Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Timothy P, Hecker"'
Publikováno v:
Oncogene. 23:3962-3971
Focal adhesion kinase (FAK) signaling may be mediated through the modulation of Ras activity. We have shown previously that grade III malignant astrocytoma biopsy samples exhibit elevated levels of FAK, and that overexpression of FAK in U-251MG malig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ed18a6787f9558cbae7c2938a79fa7
https://doi.org/10.1038/sj.onc.1207541
https://doi.org/10.1038/sj.onc.1207541
Autor:
Candece L. Gladson, Timothy P. Hecker
Publikováno v:
Frontiers in Bioscience. 8:s705-714
Focal adhesion kinase (FAK) is a non-receptor cytoplasmic tyrosine kinase that transmits signals important in modulating several cell functions, including proliferation, migration, and survival. Several different types of malignant tumors have been r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d779ed77e042f7fc12f9c5b883a135a
https://doi.org/10.2741/1115
https://doi.org/10.2741/1115
Publikováno v:
Developmental Genetics. 23:347-361
Ras1 plays a critical role in receptor tyrosine kinase (RTK) signal transduction pathways that function during Drosophila development. We demonstrate that mis-expression of constitutively active forms of Ras1 (Ras1V12) and the Sevenless (Sev) RTK (Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::418318b1d251e0645c28442b7d3bea13
https://doi.org/10.1002/(sici)1520-6408(1998)23:4<347::aid-dvg9>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1998)23:4<347::aid-dvg9>3.0.co
Autor:
Henry, Haskell, Meera, Natarajan, Timothy P, Hecker, Qiang, Ding, Jerry, Stewart, J Robert, Grammer, Candece L, Gladson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(6)
Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that has been shown to promote proliferation, migration, and invasion of several cell types in vitro, and we have shown recently that FAK promotes proliferation of malignant astrocytoma cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd92d60483148c04cc18bae12a236810
https://pubmed.ncbi.nlm.nih.gov/12796381
https://pubmed.ncbi.nlm.nih.gov/12796381
Publikováno v:
Cancer journal (Sudbury, Mass.). 9(2)
Focal adhesion kinase (FAK) is a non-receptor cytoplasmic-tyrosine kinase that is activated by several different cell surface receptors shown to be upregulated on glioblastoma cells (integrins alpha(v)beta3 and alpha(v)beta5, and the epidermal growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f156f0da055de4e7c493ab0c5ff6fffe
https://pubmed.ncbi.nlm.nih.gov/12784878
https://pubmed.ncbi.nlm.nih.gov/12784878
Autor:
Timothy P, Hecker, J Robert, Grammer, G Yancey, Gillespie, Jerry, Stewart, Candece L, Gladson
Publikováno v:
Cancer research. 62(9)
Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that on activation generates signals that can modulate crucial cell functions, including cell proliferation, migration, and survival. In vitro, overexpression of FAK has been shown to promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6de6017e09138c67bff95604846d9651
https://pubmed.ncbi.nlm.nih.gov/11980671
https://pubmed.ncbi.nlm.nih.gov/11980671
Autor:
Timothy P. Hecker, C. S. Cobbs, Candece L. Gladson, J E Jr Stewart, Z. Liu, R. Rhoden, J. R. Grammer, Qiang Ding, Dongyan Wang
Publikováno v:
Journal of cell science.
p125 focal adhesion kinase (p125FAK) is a cytoplasmic tyrosine kinase that is activated upon engagement of integrin cell adhesion receptors, and initiates several signaling events that modulate cell function in vitro. To determine the biologic role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea8a1c566e7b6ba3ce99c43c69fa8dc
https://pubmed.ncbi.nlm.nih.gov/11069767
https://pubmed.ncbi.nlm.nih.gov/11069767