Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Timothy Overton"'
Publikováno v:
Birth Defects Research. 114:1079-1091
Congenital anomalies affect over 2% of pregnancies, with congenital heart disease (CHD) the most common. Understanding of causal factors is limited. Micronutrients are essential trace elements with key roles in growth and development. We aimed to inv
Autor:
Joyce Poole, Edwin Massey, Alison Hills, John Moppett, Stephen W. Jones, Timothy Overton, Sue Search
Publikováno v:
Fetal Diagnosis and Therapy. 33:137-140
A rare case of a low incidence red cell antigen causing severe fetal allo-immune red cell disease is presented. Discussion of how this can be diagnosed and successfully managed antenatally using middle cerebral artery Doppler ultrasound and maternal
Publikováno v:
American Journal of Obstetrics and Gynecology. 186:826-831
Objectives: Our purpose was to describe the fetal loss rate and platelet dynamics in fetal alloimmune thrombocytopenia managed by serial platelet transfusions. Methods: Retrospective analysis over 10 years of consecutive pregnancies affected by fetal
Autor:
Timothy L Watts, Cesare Campagnoli, Nicholas M. Fisk, I. A. G. Roberts, Phillip R. Bennett, Timothy Overton
Publikováno v:
Blood. 95:1967-1972
The yolk sac and aorto-g ros region are well recognized as the principal sites of hematopoiesis in the developing embryo, and the liver is the principal site of hematopoiesis in the fetus. However, little is known about circulating hematopoietic stem
Autor:
Timothy Overton, Véronique Houfflin-Debarge, Hilary O’Donnell, Nicholas M. Fisk, Phillip R. Bennett
Publikováno v:
Fetal Diagnosis and Therapy. 15:102-107
DNA analysis of blood is conventionally performed on cells – plasma and serum are discarded. Free DNA has been demonstrated in serum in cancer and autoimmune disorders and in pregnancy. We investigated possible noninvasive prenatal diagnosis using
Publikováno v:
Fetal Diagnosis and Therapy. 15:118-121
Duchenne muscular dystrophy (DMD) can be diagnosed by fetal muscle biopsy and immunohistochemical staining showing the absence of dystrophin. We report a case of fetal muscle biopsy in which the needle gun was successfully fired within the fetal glut
Publikováno v:
Prenatal Diagnosis. 19:527-532
The success rate for injected umbilical vascular occlusion in the published literature exceeds 85 per cent. In this study we assessed the efficacy of two forms of injected sclerosants in achieving umbilical vessel occlusion. 12 cases of attempted ult
Publikováno v:
American Journal of Obstetrics and Gynecology. 175:455-459
OBJECTIVE: Our purpose was to devise diagnostic test(s) that determine fetal KEL1 and KEL2 genotypes. STUDY DESIGN: KEL1 and KEL2 polymorphisms are due to a single C to T base substitution at nucleotide 698 of exon 6 of KEL. This allowed us to develo
Publikováno v:
American Journal of Obstetrics and Gynecology. 175:382-387
We investigated whether reliable prenatal diagnosis is possible from fetal cells harvested transcervically in first-trimester pregnancies.Fetal cells were obtained transcervically from 87 women undergoing pregnancy termination. Fetal gender was deter
Publikováno v:
Fetal and Maternal Medicine Review. 7:159-173
Deoxyribonucleic acid (DNA) is composed of a deoxyribose backbone, the three position (3') of each deoxyribose being linked to the five position (5') of the next by a phosphodiester bond. At the two position each deoxyribose is linked to one of four