Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Timothy Nichols"'
Autor:
Rebecca Bott-Knutson, Joy Hart, Heidi Appel, Jonathan Kotinek, Paul Knox, William Ziegler, Dan Roberts, Andrea Radasanu, Timothy Nichols, Leigh Fine
Publikováno v:
Journal of the European Honors Council, Vol 6, Iss 2 (2023)
A dedicated group of honors professionals from 14 institutions across the United States of America (USA) recently emerged to strategize how honors education can prepare students to address the world’s most wicked problems--grand challenges--systema
Externí odkaz:
https://doaj.org/article/ec5a944fd5c049b2a1724513afee1cad
Autor:
Scott J. Dylla, Hans-Peter Gerber, Puja Sapra, Hadi Falahatpisheh, Frank Barletta, Robert Stull, Johannes Hampl, Orit Foord, Kathryn Loving, Timothy Nichols, Justin Lucas, Judy Lucas, Erik Upeslacis, Wenyan Zhong, Marybeth Pysz, Jeffrey Bernstein, Paul Escarpe, Elana Ernstoff, Virginia Pulito, Kiran Khandke, Sarah Fong, Monette Aujay, Marianne Santaguida, Wade Anderson, Jorge Aguilar, Albert Park, Alexander Bankovich, Marc Damelin
Purpose: Triple-negative breast cancer (TNBC) and ovarian cancer each comprise heterogeneous tumors, for which current therapies have little clinical benefit. Novel therapies that target and eradicate tumor-initiating cells (TIC) are needed to signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2ad6d27feffc9b7ae90f84aa16d05e
https://doi.org/10.1158/1078-0432.c.6523641.v1
https://doi.org/10.1158/1078-0432.c.6523641.v1
Autor:
Scott J. Dylla, Hans-Peter Gerber, Puja Sapra, Hadi Falahatpisheh, Frank Barletta, Robert Stull, Johannes Hampl, Orit Foord, Kathryn Loving, Timothy Nichols, Justin Lucas, Judy Lucas, Erik Upeslacis, Wenyan Zhong, Marybeth Pysz, Jeffrey Bernstein, Paul Escarpe, Elana Ernstoff, Virginia Pulito, Kiran Khandke, Sarah Fong, Monette Aujay, Marianne Santaguida, Wade Anderson, Jorge Aguilar, Albert Park, Alexander Bankovich, Marc Damelin
Supplementary Figures 1-4. Supplementary Figure 1. Analysis of EFNA4 copy number in breast and hepatocellular carcinoma. Supplementary Figure 2. Characterization of PF-06647263 conjugates. Supplementary Figure 3. Biomarkers of PF-06647263 activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d14fed96e16e890f6829719918e5df
https://doi.org/10.1158/1078-0432.22457655.v1
https://doi.org/10.1158/1078-0432.22457655.v1
Autor:
Mark Ozeck, Timothy Nichols, Akshata Udyavar, Thomas A Paul, Tao Xie, Shikhar Sharma, Wen Yan, Jessica Frey, Chi-Yeh Chung
Publikováno v:
Molecular Oncology. 16:1309-1328
Small cell lung cancer (SCLC) is a heterogeneous disease, consisting of intra-tumoral and inter-tumoral neuroendocrine (ASCL1 and/or NEUROD1), mesenchymal-like, and YAP-driven transcriptional states. Lysine-specific demethylase 1 (LSD1; also known as
Autor:
Wen Yan, Mark Ozeck, Tao Xie, Akshata Udyavar, Timothy Nichols, Thomas A Paul, Shikhar Sharma, Chi-Yeh Chung, Jessica Frey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cc2b6772e2c415d8c023673d8a9327
https://doi.org/10.1002/1878-0261.13124/v2/response1
https://doi.org/10.1002/1878-0261.13124/v2/response1
Autor:
James S. Hardwick, Ping Wei, Joan Cao, Hui Wang, Todd VanArsdale, Scott L. Weinrich, Paul A. Rejto, Shibing Deng, Goldie Y. L. Lui, Zhou Zhu, Timothy Nichols
Publikováno v:
Oncogene. 38:4125-4141
The CDK4/6 inhibitor palbociclib reduces tumor growth by decreasing retinoblastoma (RB) protein phosphorylation and inducing cell cycle arrest at the G1/S phase transition. Palbociclib in combination with anti-hormonal therapy brings significant bene
Autor:
Mark Ozeck, Tao Xie, Chi-Yeh Chung, Wen Yan, Timothy Nichols, Thomas A Paul, Akshata Udyavar, Jessica Frey, Shikhar Sharma
BackgroundSCLC is a heterogeneous disease, consisting of intra-tumoral and inter-tumoral neuroendocrine (ASCL1/NEUROD1), mesenchymal-like, and YAP-driven transcriptional states. Lysine-specific demethylase 1 (LSD1/KDM1A) inhibitors have recently been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aefe2ac7172dcc01caf596b1c5c64dd
https://doi.org/10.21203/rs.3.rs-249776/v1
https://doi.org/10.21203/rs.3.rs-249776/v1
Publikováno v:
2013 ASEE Annual Conference & Exposition Proceedings.
Autor:
Sripad Ram, Y.S. Choi, Sy Cho, James S. Hardwick, Timothy Nichols, Pamela Vizcarra, Ying Ding, J. Yu, Keith A. Ching, Young-Ae Park, Zhengyan Kan, Eric L. Powell, S-H Lee
Publikováno v:
Cancer Research. 78:P2-07
The advent of immuno-oncology (IO) therapies has made it an imperative to characterize intratumoral immune microenvironment in addition to oncogenic alterations through molecular profiling of the tumor. To elucidate the baseline profiles of tumor inf
Autor:
Timothy Nichols, David Clemmons
Summary: This assay is used by the DiaComp to measure glucose tolerance and insulin sensitivity in pigs. Diabetic Complications: Reference: 1. Bergman RN, Finegood DT, Ader M: Assessment of insulin sensitivity in vivo. Endocr Rev 1985, 6:45-86.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67d6635cd732fc105084f851388ff1f4
https://doi.org/10.17504/protocols.io.8e8hthw
https://doi.org/10.17504/protocols.io.8e8hthw