Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Timothy N. W. Jackson"'
Autor:
Cassandra M. Modahl, Summer Xia Han, Jory van Thiel, Candida Vaz, Nathan L. Dunstan, Seth Frietze, Timothy N. W. Jackson, Stephen P. Mackessy, R. Manjunatha Kini
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background Venom systems are ideal models to study genetic regulatory mechanisms that underpin evolutionary novelty. Snake venom glands are thought to share a common origin, but there are major distinctions between venom toxins from the medi
Externí odkaz:
https://doaj.org/article/e32eb2a330b14f838558a0ddbc89daee
Autor:
Ivan Koludarov, Mariana Velasque, Tobias Senoner, Thomas Timm, Carola Greve, Alexander Ben Hamadou, Deepak Kumar Gupta, Günter Lochnit, Michael Heinzinger, Andreas Vilcinskas, Rosalyn Gloag, Brock A. Harpur, Lars Podsiadlowski, Burkhard Rost, Timothy N. W. Jackson, Sebastien Dutertre, Eckart Stolle, Björn M. von Reumont
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-27 (2023)
Abstract Background Venoms, which have evolved numerous times in animals, are ideal models of convergent trait evolution. However, detailed genomic studies of toxin-encoding genes exist for only a few animal groups. The hyper-diverse hymenopteran ins
Externí odkaz:
https://doaj.org/article/d4e819b6aea4481dbc47399220d9b769
Autor:
Ivan Koludarov, Tobias Senoner, Timothy N. W. Jackson, Daniel Dashevsky, Michael Heinzinger, Steven D. Aird, Burkhard Rost
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Three-finger toxins (3FTXs) are a functionally diverse family of toxins, apparently unique to venoms of caenophidian snakes. Although the ancestral function of 3FTXs is antagonism of nicotinic acetylcholine receptors, redundancy conferred by
Externí odkaz:
https://doaj.org/article/6575a48432e64e678e61c3d04a931b8f
Autor:
Luis L. Alonso, Jory van Thiel, Julien Slagboom, Nathan Dunstan, Cassandra M. Modahl, Timothy N. W. Jackson, Saer Samanipour, Jeroen Kool
Publikováno v:
Toxins, Vol 16, Iss 4, p 181 (2024)
This study provides a new methodology for the rapid analysis of numerous venom samples in an automated fashion. Here, we use LC-MS (Liquid Chromatography–Mass Spectrometry) for venom separation and toxin analysis at the accurate mass level combined
Externí odkaz:
https://doaj.org/article/9990a06817e94667b17a6686411c559a
Autor:
Afsana Afroz, Bodrun Naher Siddiquea, Aishwarya Narendra Shetty, Timothy N. W. Jackson, Andrew D. Watt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 2 (2023)
Background Snakebite envenoming is a serious and life-threatening medical condition that predominantly affects people living in rural communities across Africa, Asia, and Latin America. As our climate changes, there is a growing concern that negative
Externí odkaz:
https://doaj.org/article/521261c5165949d88060ecf60723c7ad
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ebebbd78cb8f4918860cf7bcd610a898
Publikováno v:
Toxins, Vol 15, Iss 4, p 251 (2023)
Snake venoms are primarily used to subjugate prey, and consequently, their evolution has been shown to be predominantly driven by diet-related selection pressure. Venoms tend to be more lethal to prey than non-prey species (except in cases of toxin r
Externí odkaz:
https://doaj.org/article/67ce50b5b331425b8033bb7669f14477
Autor:
Jory van Thiel, Luis L. Alonso, Julien Slagboom, Nathan Dunstan, Roel M. Wouters, Cassandra M. Modahl, Freek J. Vonk, Timothy N. W. Jackson, Jeroen Kool
Publikováno v:
Toxins, Vol 15, Iss 1, p 74 (2023)
Snake venoms are complex mixtures of toxins that differ on interspecific (between species) and intraspecific (within species) levels. Whether venom variation within a group of closely related species is explained by the presence, absence and/or relat
Externí odkaz:
https://doaj.org/article/b7100fa090eb4e798f6caea896e6292f
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Human envenoming by Australian brown snakes (Pseudonaja spp.) may result in potentially life-threatening hypotension and subsequent cardiovascular collapse. There have been relatively few studies of the cardiovascular and sympathetic effects of Pseud
Externí odkaz:
https://doaj.org/article/596653080cfc4b7aa01573b3ee78ba8b
Publikováno v:
Toxins, Vol 14, Iss 6, p 420 (2022)
Venom is a dynamic trait that has contributed to the success of numerous organismal lineages. Predominantly composed of proteins, these complex cocktails are deployed for predation and/or self-defence. Many non-toxic physiological proteins have been
Externí odkaz:
https://doaj.org/article/6e858471cb524756b236846de878641d