Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Timothy N Phoenix"'
Autor:
Jennifer Patritti-Cram, Eric P. Rahrmann, Tilat A. Rizvi, Katherine C. Scheffer, Timothy N. Phoenix, David A. Largaespada, Nancy Ratner
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110294- (2024)
Summary: The blood-nerve-barrier (BNB) that regulates peripheral nerve homeostasis is formed by endoneurial capillaries and perineurial cells surrounding the Schwann cell (SC)-rich endoneurium. Barrier dysfunction is common in human tumorigenesis, in
Externí odkaz:
https://doaj.org/article/b2e4f7d4622f4f9db1bac7a662c21301
Autor:
Shane A Liddelow, Sally Temple, Kjeld Møllgård, Renate Gehwolf, Andrea Wagner, Hannelore Bauer, Hans-Christian Bauer, Timothy N Phoenix, Katarzyna M Dziegielewska, Norman R Saunders
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33554 (2012)
Exchange mechanisms across the blood-cerebrospinal fluid (CSF) barrier in the choroid plexuses within the cerebral ventricles control access of molecules to the central nervous system, especially in early development when the brain is poorly vascular
Externí odkaz:
https://doaj.org/article/ff6270a42b8b478ba990fabcf3a33d39
Autor:
Aniruddha S. Karve, Janki M. Desai, Sidharth N. Gadgil, Nimita Dave, Trisha M. Wise-Draper, Gary A. Gudelsky, Timothy N. Phoenix, Biplab DasGupta, Lalanthica Yogendran, Soma Sengupta, David R. Plas, Pankaj B. Desai
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3217 (2024)
A glioblastoma (GBM) is one of the most aggressive, infiltrative, and treatment-resistant malignancies of the central nervous system (CNS). The current standard of care for GBMs include maximally safe tumor resection, followed by concurrent adjuvant
Externí odkaz:
https://doaj.org/article/d0a4c09af4b5404385800fc2b3d6571b
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741da86f253c6e42c0401531e9509b90
https://doi.org/10.1158/0008-5472.c.6514136.v1
https://doi.org/10.1158/0008-5472.c.6514136.v1
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
Purpose:Diffuse intrinsic pontine glioma (DIPG) is an incurable type of pediatric brain cancer, which in the majority of cases is driven by mutations in genes encoding histone 3 (H3K27M). We here determined the preclinical therapeutic potential of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426e325eb37e62297bb71b9385084f22
https://doi.org/10.1158/1078-0432.c.6529571
https://doi.org/10.1158/1078-0432.c.6529571
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c77d20498973705d006fee266ee01a
https://doi.org/10.1158/0008-5472.22432439.v1
https://doi.org/10.1158/0008-5472.22432439.v1
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
Legends pertaining to supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f3f0b188d7068471497ed95dac109a
https://doi.org/10.1158/1078-0432.22477094
https://doi.org/10.1158/1078-0432.22477094
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b86034115df2220900de572ba0818
https://doi.org/10.1158/0008-5472.22432385
https://doi.org/10.1158/0008-5472.22432385
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
File containing all supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081cd3246c4a6479a7a296a32247511d
https://doi.org/10.1158/1078-0432.22477091
https://doi.org/10.1158/1078-0432.22477091
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
Sequences of shRNA constructs used in the present study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0487d8a1c4c34ee702f686689b68552b
https://doi.org/10.1158/1078-0432.22477088.v1
https://doi.org/10.1158/1078-0432.22477088.v1