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pro vyhledávání: '"Timothy McLennan"'
Autor:
Timothy McLennan-Smith
Publikováno v:
El Sawah, S. (ed.) MODSIM2019, 23rd International Congress on Modelling and Simulation..
Autor:
Timothy McLennan
Publikováno v:
Anatomical sciences educationLITERATURE CITED. 13(3)
Publikováno v:
Endocrinology. 161(2)
The gonadotrophin-releasing hormone (GnRH) pulse generator drives pulsatile luteinizing hormone (LH) secretion essential for fertility. However, the constraints within which the pulse generator operates to drive efficient LH pulsatility remain unclea
Publikováno v:
Neuroendocrinology. 105:157-169
Background/Aims: Arcuate nucleus (ARN) γ-aminobutyric acid (GABA) neurons are implicated in many critical homeostatic mechanisms, from food intake to fertility. To determine the functional relevance of ARN GABA neurons, it is essential to define the
Autor:
Katja Czieselsky, Robert Porteous, Richard Piet, Timothy McLennan, Allan E. Herbison, Bruna Kalil
A population of kisspeptin-GABA coexpressing neurons located in the rostral periventricular area of the third ventricle (RP3V) is believed to activate gonadotropin-releasing hormone (GnRH) neurons to generate the luteinizing hormone (LH) surge trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3975a445b5e274d5853ed03a3b91e1f9
https://europepmc.org/articles/PMC6596098/
https://europepmc.org/articles/PMC6596098/
Autor:
Joon S. Kim, William H. Colledge, Grace Kane, Richard Piet, Su Young Han, Jenny Clarkson, Jamie Ng, Karl J. Iremonger, Robert Porteous, Allan E. Herbison, Timothy McLennan
The pulsatile release of luteinizing hormone (LH) is critical for mammalian fertility. However, despite several decades of investigation, the identity of the neuronal network generating pulsatile reproductive hormone secretion remains unproven. We us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03d2e5451c4039a474b3d238a454f83
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(42)
Normal reproductive functioning in mammals depends upon gonadotropin-releasing hormone (GnRH) neurons generating a pulsatile pattern of gonadotropin secretion. The neural mechanism underlying the episodic release of GnRH is not known, although recent