Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Timothy M. Tucey"'
Autor:
Christopher McCrory, Jiyoti Verma, Timothy M. Tucey, Rachael Turner, Harshini Weerasinghe, Traude H. Beilharz, Ana Traven
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTMicrobes are exposed to nutritional and stress challenges in their environmental and host niches. To rise to these challenges, they regulate transcriptional programs that enable cellular adaptation. For instance, metabolite concentrations reg
Externí odkaz:
https://doaj.org/article/81b745c522a942899b1565bde7d0a50b
Autor:
Qi Wang, Jiyoti Verma, Nikolina Vidan, Yanan Wang, Timothy M. Tucey, Tricia L. Lo, Paul F. Harrison, Michael See, Angavai Swaminathan, Karl Kuchler, Michael Tscherner, Jiangning Song, David R. Powell, Mary Sopta, Traude H. Beilharz, Ana Traven
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Identification of multiple histone acylations diversifies transcriptional control by metabolism, but their functions are incompletely defined. Here we report evidence of histone crotonylation in the human fungal pathogen Candida albicans. We
Externí odkaz:
https://doaj.org/article/95f7d75aca524f688ecbafc907b55b71
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The interactions of mitochondria with the endoplasmic reticulum (ER) are crucial for maintaining proper mitochondrial morphology, function and dynamics. This enables cells to utilize their mitochondria optimally for energy production and anabolism, a
Externí odkaz:
https://doaj.org/article/581a82fac6fb40a9a7cd8ccfc36611db
Autor:
Timothy M. Tucey, Jiyoti Verma-Gaur, Julie Nguyen, Victoria L. Hewitt, Tricia L. Lo, Miguel Shingu-Vazquez, Avril A. B. Robertson, James R. Hill, Filomena A. Pettolino, Travis Beddoe, Matthew A. Cooper, Thomas Naderer, Ana Traven
Publikováno v:
mSphere, Vol 1, Iss 3 (2016)
ABSTRACT The pathogenic yeast Candida albicans escapes macrophages by triggering NLRP3 inflammasome-dependent host cell death (pyroptosis). Pyroptosis is inflammatory and must be tightly regulated by host and microbe, but the mechanism is incompletel
Externí odkaz:
https://doaj.org/article/9250ecd36c7f4b649bfd1f5e5382377f
Autor:
Ralf B. Schittenhelm, Timothy M. Tucey, Ana Traven, Madhu Shankar, Santanu K. Ghosh, Vinutha K. Balachandra, Jiyoti Verma
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 11, p e1009071 (2020)
PLoS Genetics, Vol 16, Iss 11, p e1009071 (2020)
Regulation of gene expression programs is crucial for the survival of microbial pathogens in host environments and for their ability to cause disease. Here we investigated the epigenetic regulator RSC (Remodels the Structure of Chromatin) in the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff15c79c10b84fcfb4a669a87d1120ea
http://europepmc.org/articles/PMC7671503
http://europepmc.org/articles/PMC7671503
Autor:
Françios Alwyn Benson Olivier, Thomas Naderer, Timothy M. Tucey, Ana Traven, Tricia L. Lo, Jiyoti Verma, Avril A. B. Robertson
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 8, p e1008695 (2020)
PLoS Pathogens, Vol 16, Iss 8, p e1008695 (2020)
The NLRP3 inflammasome has emerged as a central immune regulator that senses virulence factors expressed by microbial pathogens for triggering inflammation. Inflammation can be harmful and therefore this response must be tightly controlled. The mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22ff7aaf270006608d72e263b3dca4e
http://europepmc.org/articles/PMC7433900
http://europepmc.org/articles/PMC7433900
Publikováno v:
Genetics
A leading objective in biology is to identify the complete set of activities performed by each gene. Identification of a comprehensive set of separation...
A leading objective in biology is to identify the complete set of activities that each ge
A leading objective in biology is to identify the complete set of activities that each ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f3703aa19c6c16382fee1ceb81b69e
https://doi.org/10.1534/genetics.117.300145
https://doi.org/10.1534/genetics.117.300145
Autor:
David R. Powell, Michael Tscherner, Tricia L. Lo, Karl Kuchler, Qi Wang, Michael See, Jiangning Song, Yanan Wang, Traude H. Beilharz, Nikolina Vidan, Mary Sopta, Timothy M. Tucey, Angavai Swaminathan, Ana Traven, Jiyoti Verma, Paul Harrison
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp-(2020)
Summary: Identification of multiple histone acylations diversifies transcriptional control by metabolism, but their functions are incompletely defined. Here we report evidence of histone crotonylation in the human fungal pathogen Candida albicans. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6487747efd32c96db7e898298b94a053
https://pubmed.ncbi.nlm.nih.gov/32320659
https://pubmed.ncbi.nlm.nih.gov/32320659
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The interactions of mitochondria with the endoplasmic reticulum (ER) are crucial for maintaining proper mitochondrial morphology, function and dynamics. This enables cells to utilize their mitochondria optimally for energy production and anabolism, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cbb0e35d608cb00156c168ca1d7aad
https://doi.org/10.3389/fmicb.2017.02555
https://doi.org/10.3389/fmicb.2017.02555
Autor:
Adele Barugahare, Michael J. Hickey, Robert T. Wheeler, Paul Harrison, Jiyoti Verma, Allison K. Scherer, Timothy M. Tucey, David R. Powell, Ana Traven, Thomas Naderer, Tricia L. Lo, Sarah L. Snelgrove, Traude H. Beilharz
Publikováno v:
Cell metabolism. 27(5)
Summary To fight infections, macrophages undergo a metabolic shift whereby increased glycolysis fuels antimicrobial inflammation and killing of pathogens. Here we demonstrate that the pathogen Candida albicans turns this metabolic reprogramming into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9740cdc27bdae1e5bbb46016ddf867e
https://pubmed.ncbi.nlm.nih.gov/29719235
https://pubmed.ncbi.nlm.nih.gov/29719235