Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Timothy M. Thomson"'
Autor:
Maria Nuria Peralta-Moreno, Yago Mena, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Olga Abian, Adrian Velazquez-Campoy, Timothy M. Thomson, Marta Pinto, José M. Granadino-Roldán, Maria Santos Tomas, Juan J. Perez, Jaime Rubio-Martinez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6119 (2024)
The development of specific antiviral therapies targeting SARS-CoV-2 remains fundamental because of the continued high incidence of COVID-19 and limited accessibility to antivirals in some countries. In this context, dark chemical matter (DCM), a set
Externí odkaz:
https://doaj.org/article/112df38d75b74c1394a53416a4e0597f
Autor:
Timothy M. Thomson
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bc2aa05f94614ddc9d37c1efb8c62167
Autor:
Emily Toscano-Guerra, Mónica Martínez Gallo, Iria Arrese-Muñoz, Anna Giné, Noelia Díaz-Troyano, Pablo Gabriel-Medina, Mar Riveiro-Barciela, Moisés Labrador-Horrillo, Fernando Martinez-Valle, Adrián Sánchez Montalvá, Manuel Hernández-González, Ricardo Pujol Borrell, Francisco Rodríguez-Frias, Roser Ferrer, Timothy M. Thomson, Rosanna Paciucci
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background SARS-CoV-2 infection portends a broad range of outcomes, from a majority of asymptomatic cases to a lethal disease. Robust correlates of severe COVID-19 include old age, male sex, poverty, and co-morbidities such as obesity, diabe
Externí odkaz:
https://doaj.org/article/2d4c6333609949d392ebc109f5d6665c
Autor:
Leire Pedrosa, Carles Foguet, Helena Oliveres, Iván Archilla, Marta García de Herreros, Adela Rodríguez, Antonio Postigo, Daniel Benítez-Ribas, Jordi Camps, Miriam Cuatrecasas, Antoni Castells, Aleix Prat, Timothy M. Thomson, Joan Maurel, Marta Cascante
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Existing immune signatures and tumor mutational burden have only modest predictive capacity for the efficacy of immune check point inhibitors. In this study, we developed an immune-metabolic signature suitable for personalized ICI therapies. A classi
Externí odkaz:
https://doaj.org/article/cc714daff1e1497f851797bec7a612cf
Autor:
Maria Nuria Peralta-Moreno, Vanessa Anton-Muñoz, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Olga Abian, Adrian Velazquez-Campoy, Timothy M. Thomson, José Manuel Granadino-Roldán, Claudia Machicado, Jaime Rubio-Martinez
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 585 (2023)
Over 750 million cases of COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), have been reported since the onset of the global outbreak. The need for effective treatments has spurred intensive research for therapeuti
Externí odkaz:
https://doaj.org/article/1390327187704505aca265db9fd93a30
Autor:
Valérie Françoise Smolders, Erika Zodda, Paul H. A. Quax, Marina Carini, Joan Albert Barberà, Timothy M. Thomson, Olga Tura-Ceide, Marta Cascante
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2019)
Cardiovascular diseases (CVD) are the leading cause of death worldwide. CVD comprise a range of diseases affecting the functionality of the heart and blood vessels, including acute myocardial infarction (AMI) and pulmonary hypertension (PH). Despite
Externí odkaz:
https://doaj.org/article/28a38af9e2fd442bb7b289d51b4428ec
Autor:
Luz Camacho, Óscar Meca-Cortés, José Luis Abad, Simón García, Nuria Rubio, Alba Díaz, Toni Celià-Terrassa, Francesca Cingolani, Raquel Bermudo, Pedro L. Fernández, Jerónimo Blanco, Antonio Delgado, Josefina Casas, Gemma Fabriàs, Timothy M. Thomson
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 5, Pp 1207-1220 (2013)
Acid ceramidase (AC) catalyzes the hydrolysis of ceramide into sphingosine, in turn a substrate of sphingosine kinases that catalyze its conversion into the mitogenic sphingosine-1-phosphate. AC is expressed at high levels in several tumor types and
Externí odkaz:
https://doaj.org/article/2b991f7a1bd34503b693968a8ce2f2fe
Autor:
Erika Zodda, Olga Tura-Ceide, Nicholas L. Mills, Josep Tarragó-Celada, Marina Carini, Timothy M Thomson, Marta Cascante
Compelling evidence has accumulated for the role of oxidative stress on the endothelial cell (EC) dysfunction underlying acute coronary syndromes. However, understanding the metabolic determinants of EC dysfunction has been hampered by the scarcity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6500f8cf220fc31d2493efaf25e333d
https://doi.org/10.1101/2023.02.28.530418
https://doi.org/10.1101/2023.02.28.530418
Autor:
Jaime, Rubio-Martínez, Ana, Jiménez-Alesanco, Laura, Ceballos-Laita, David, Ortega-Alarcón, Sonia, Vega, Cristina, Calvo, Cristina, Benítez, Olga, Abian, Adrián, Velázquez-Campoy, Timothy M, Thomson, José Manuel, Granadino-Roldán, Patricia, Gómez-Gutiérrez, Juan J, Pérez
Publikováno v:
Journal of chemical information and modeling. 61(12)
SARS-CoV-2 is a type of coronavirus responsible for the international outbreak of respiratory illness termed COVID-19 that forced the World Health Organization to declare a pandemic infectious disease situation of international concern at the beginni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f28e1b5eab45ef7d04e036d3e4add04c
https://pubmed.ncbi.nlm.nih.gov/34806382
https://pubmed.ncbi.nlm.nih.gov/34806382
Autor:
Emily Toscano-Guerra, Mónica Martínez-Gallo, Iria Arrese-Muñoz, Anna Giné, Noelia Díaz-Troyano, Pablo Gabriel-Medina, Mar Riveiro-Barciela, Moisés Labrador-Horrillo, Fernando Martinez-Valle, Adrián Sánchez Montalvá, Manuel Hernández-González, Ricardo Pujol Borrell, Francisco Rodríguez-Frias, Roser Ferrer, Timothy M. Thomson, Rosanna Paciucci
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientia
Digital.CSIC. Repositorio Institucional del CSIC
instname
Universitat Autònoma de Barcelona
Scientia
Digital.CSIC. Repositorio Institucional del CSIC
instname
Background SARS-CoV-2 infection portends a broad range of outcomes, from a majority of asymptomatic cases to a lethal disease. Robust correlates of severe COVID-19 include old age, male sex, poverty, and co-morbidities such as obesity, diabetes, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01184b18de515ef7286b7902a3787949
https://doi.org/10.1101/2021.06.29.21259693
https://doi.org/10.1101/2021.06.29.21259693