Rising resistance of urinary tract pathogens in children: a cause for concern

Autor: Mansoor Ahmed, Wan Norafifah Wan Long, Timothy M Reynolds, Sidra Javed

Publikováno v: Irish Journal of Medical Science (1971 -). 191:279-282

Urinary tract infection (UTI) is one of the common infections in childhood. Prompt diagnosis and treatment reduces the risk of complications. The choice of antibiotic to treat UTI varies from region to region. Rational use and appropriately chosen an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b428649519e60949f3ad7166105432
https://doi.org/10.1007/s11845-021-02531-4

COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study

Autor: Amanda Semper, P Burns, K Gajee, Amoolya Vusirikala, L Moore, S Joyce, Paul Klenerman, R Longfellow, R Matthews, Jacqueline Hewson, L Prentice, Alastair Grant, Edgar Wellington, A Tengbe, S Ambalkar, Alex Soriano, I Karagiannis, A Ashby, C Carr, O Kay, B Larru, Manjula Meda, T Lewis, H Aziz, R Chaudhuri, Ioannis Karagiannis, Martin S. Williams, J Conneely, Tim Planche, A M Moody, A Ho, Ashley Otter, K McLelland-Brooks, N Todd, J Alderton, Matthew T. G. Holden, A Boulos, T DeSilva, A Rajgopal, R Pritchard Jones, J Khawam, SC Bain, V J Hall, S Birch, Sarah Foulkes, MA Chand, CS Brown, P Cowling, K Hollinshead, M Halkes, M Ramsay, Cathy Rowe, Colin S Brown, Mark Joseph, N Slawson, Blanche Oguti, L Hall, J Russell, Ayoub Saei, Linda Partridge, Shahjahan Miah, L Coke, Steven Platt, Angie Lackenby, Victoria Hall, M Sartaj, L Keen, A Saei, T Chin, C Thomas, Louise Robinson, Christopher W Holmes, C Subudhi, M Beekes, R Laugharne, Diane Wycherley, R.J. Shorten, R Temple-Purcell, H Chenoweth, V Maxwell, A Atti, Padmasayee Papineni, J Giles, K. Black, M Booth, Jane Democratis, D McCracken, L Cromey, Peter Kirwan, D Delgado, D Hilton, R Crosby-Nwaobi, Susanna Dunachie, A Roebuck, G Sebbage, S Foulkes, K Tempeton, Edward M. Smith, J Murira, Ajay Chawla, Joanna Ellis, J Lopez-Bernal, S Jose, Nick Andrews, A Charlett, Bjl Burton, I Sinanovic, N Aldridge, Katie Jeffery, Gretchen A Stevens, Y Ellis, J Powell, Shân Davies, Alan Jackson, Jonathan L. Heeney, A Dave, B Oguti, A Swan, EA Sheridan, Sara Bennett, Susan Hopkins, T Donaghy, Sakib Rokadiya, Jasmin Islam, S Akhtar, J Mouland, P Domingos, J Harwood, Christian Gabriel, Christopher J A Duncan, Stephen R. Williams, S Hams, E Cameron, F Westwell, Keith D. James, Meaghan Kall, K Pagget, Justin Pepperell, Robert Tilley, A O'Kelly, S Horne, K Potts, S Gormley, F Sanderson, Sharen Painter, S. Stone, Mariyam Mirfenderesky, Tabitha Mahungu, S Baillon, R Kyffin, S Organ, S Brake, Andre Charlett, S Brand, D Browne, J Ledger, Meera Chand, Madhumita Shrotri, Michael J. Cole, Debra Padgett, M Lee, Martin Wiselka, A M O'Connell, Minal Patel, Katie Munro, L Haahr, T M Byrne, J Gunn, Naomi F. Walker, P Bakker, P Cieciwa, Stephen Winchester, N Chitalia, B Wadams, Michael P. Murphy, P Staves, Ken Agwuh, Cressida Auckland, Sarah Meisner, Ejm Monk, J Howard, C Duff, Susan R. Hopkins, N Andrews, J Elliott, K Braithwaite, AJ Plant, M Howard, Sharon Campbell, A Nissr, Stuart K. Roberts, D Pople, G Maloney, L Mabey, T Bailey, Simon Warren, S Orr, Alex Horsley, J Radmore, Lance Turtle, Helen V. Smith, Badrinathan Chandrasekaran, C Forsyth, R Lear, A Roynon, Claire Price, Ana Atti, Maria Zambon, Stephen R Knight, Jeremy N. Day, Katja Hoschler, Aarti Shah, Chetan Parmar, Rajeka Lazarus, M Lattimore, Julia Stowe, J Aeron-Thomas, J Tomlinson, L Allsop, A Abdelrazik, C Laven, Silvia D'Arcangelo, Z Naheed, A Cochrane, L Price, Emily MacNaughton, K Munro, E King, Chris Jones, S Mcwilliam, G Boyd, Caroline Kerrison, S Hamer, David W Eyre, T Trinick, J Marrs, F Adair, H Coles, Jameel Khawam, S Board, Gordon B. Mills, Mary Ramsay, Nada Ahmed, D Brooking, J Northfield, Jamie Lopez-Bernal, N Kalakonda, D Ironmonger, Shazaad Ahmad, S Taylor, A Watt, J Graves, D Flanagan, Helen Baxendale, R Penn, Louise Berry, D Corrigan, C Favager, M E Green, V Bateman, N Mahabir, J Osbourne, K Gray, Eleri Wilson-Davies, S Pai, I Knox, S Tonge, G Pottinger, M Brazil, Hayley Crawford, K Court, Daniel Harvey, Brendan A I Payne, A Arenas-Pinto, E Hanna, Robin Gopal, Henrietta U. Okafor, Frances L. Game, A Cross, Benjamin J. Stewart, Kevin K. Brown, Timothy M Reynolds, ED Lacey, V Irvine, Julie V. Robotham, A Lloyd, M Aga, D Brennan, C Loughrey, K Shipman, I Del Rosario, Stephen J. Fowler, H Hodgson, K Nimako, Ruth Simmons, Aditi Pai, S Stewart, R Druyeh, Nicholas J. White, A Bexley, E Defever, G Harrison, Trevor J. Barnes, N Wong, Natalie Gillson, S Khanduri, Sarah Wallace, M O'Kane, A Whileman, Arthur Taylor, A Houston, R Sierra, N Elumogo, Ezra Linley, A Higham, J Islam, J Ashcroft, E Underhill, D Camero, Stacey Donaldson, N Gillson, N Osuji, M Z Qazzafi, J Birch, C Sinclair, E Wellington, D Dhasmana, C Pegg, Reuben McGregor, C Norman, Alison Rodger, D Adeboyeku, L E Hughes, H Johnstone, L Gallego, Tim Brooks, Adrian Hawkins, A Selassi, P Swift, P Mercer, A Cowley, A Gibson, P Harrington, A Broadley, P Ridley, S Evans, Ywj Huang

Summary Background BNT162b2 mRNA and ChAdOx1 nCOV-19 adenoviral vector vaccines have been rapidly rolled out in the UK from December, 2020. We aimed to determine the factors associated with vaccine coverage for both vaccines and documented the vaccin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379bd8d61173536a1da08d3f37b30695
https://ora.ox.ac.uk/objects/uuid:5a2a7448-4a7a-4e81-abb9-b93e119c6113

Genetic risk scores in lipid disorders

Autor: Anthony S. Wierzbicki, Timothy M Reynolds

Publikováno v: Current Opinion in Cardiology. 34:406-412

Purpose of review Extensive work has gone into understanding the genetics of cardiovascular disease (CVD) and implicating genes involved in hyperlipidaemia. Translation into routine practise involves using genetic risk scores (GRS) to identify high-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920b7b2c7129fcef3cf24e74d220cedb
https://doi.org/10.1097/hco.0000000000000623

Identification of patients with Fabry disease using routine pathology results: PATHFINDER (eGFR) study

Autor: Karen Tylee, Kathryn L Booth, Timothy M Reynolds, Anthony S. Wierzbicki

Publikováno v: International Journal of Clinical Practice. 75

Aims Lysosomal α-galactosidase A deficiency (Fabry disease (FD)) was considered an X-linked recessive disorder but is now viewed as a variable penetrance dominant trait. The prevalence of FD is 1 in 40 000-117 000 but the ascertainment of late-onset

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbda55120f51367aeea80247ed64831c
https://doi.org/10.1111/ijcp.13672

An update on trials of novel lipid-lowering drugs

Autor: Anthony S. Wierzbicki, Timothy M Reynolds, Adie Viljoen

Publikováno v: Current Opinion in Cardiology. 33:416-422

PURPOSE OF REVIEW A number of novel trials have assessed the efficacy of new lipid-lowering therapies in cardiovascular disease (CVD). RECENT FINDINGS Proprotein convertase subtilisin kexin-9 inhibitors reduce low-density lipoprotein cholesterol (LDL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd1bc9451b3fa9f91f116b54c445175
https://doi.org/10.1097/hco.0000000000000518