Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Timothy M. Rawson"'
Autor:
Richard C. Wilson, Alaa Riezk, Paul Arkell, Damien Ming, Ryan Armiger, Victoria Latham, Mark J. Gilchrist, Anne-Grete Märtson, William W. Hope, Alison H. Holmes, Timothy M. Rawson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In the face of increasing antimicrobial tolerance and resistance there is a global obligation to optimise oral antimicrobial dosing strategies including narrow spectrum penicillins, such as penicillin-V. We conducted a randomised, crossover
Externí odkaz:
https://doaj.org/article/97703b0946e84335a208e8fd496377c1
Autor:
William J. Bolton, Richard Wilson, Mark Gilchrist, Pantelis Georgiou, Alison Holmes, Timothy M. Rawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Antimicrobial resistance (AMR) and healthcare associated infections pose a significant threat globally. One key prevention strategy is to follow antimicrobial stewardship practices, in particular, to maximise targeted oral therapy and reduce
Externí odkaz:
https://doaj.org/article/2fe26817ab6d41df985a14a44ebb4456
Publikováno v:
Infection Prevention in Practice, Vol 5, Iss 4, Pp 100313- (2023)
Introduction: Central line-associated bloodstream infections (CLABSI) are an important clinical and public health issue, impacted by the purported increase in healthcare-associated infections (including CLABSI) during the COVID-19 pandemic. This revi
Externí odkaz:
https://doaj.org/article/1665d014d228436d9f6559385705fec5
Autor:
Luke S. P. Moore, Maria Virginia Villegas, Eric Wenzler, Timothy M. Rawson, Rita O. Oladele, Yohei Doi, Anucha Apisarnthanarak
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 6, Pp 1445-1463 (2023)
Abstract Despite technological advancements in infectious disease rapid diagnostic tests (RDTs) and use to direct therapy at the per-patient level, RDT utilisation in antimicrobial stewardship programmes (ASPs) is variable across low-to-middle income
Externí odkaz:
https://doaj.org/article/64c0e6c241b74b5c8c7276ebb77c0fd6
Autor:
Rakhee Mistry, Timothy M. Rawson, Oliver Troise, Nabeela Mughal, Luke S. P. Moore, Stephen Hughes
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoint criteria for methicillin-susceptible Staphylococcus aureus (MSSA) treatment with ceftriaxone are based upon high dose (4 g/day) rather than standard do
Externí odkaz:
https://doaj.org/article/a70932601443431b960562f2fd864b40
Autor:
Damien K. Ming, Ashleigh C. Myall, Bernarnd Hernandez, Andrea Y. Weiße, Robert L. Peach, Mauricio Barahona, Timothy M. Rawson, Alison H. Holmes
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background To characterise the longitudinal dynamics of C-reactive protein (CRP) and Procalcitonin (PCT) in a cohort of hospitalised patients with COVID-19 and support antimicrobial decision-making. Methods Longitudinal CRP and PCT concentra
Externí odkaz:
https://doaj.org/article/8cc97ea33545413e98a599626bbe4f0d
Autor:
William J. Bolton, Timothy M. Rawson, Bernard Hernandez, Richard Wilson, David Antcliffe, Pantelis Georgiou, Alison H. Holmes
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
The decision on when it is appropriate to stop antimicrobial treatment in an individual patient is complex and under-researched. Ceasing too early can drive treatment failure, while excessive treatment risks adverse events. Under- and over-treatment
Externí odkaz:
https://doaj.org/article/df30422d9c86484d95f09d61081033b8
Autor:
Pau Herrero, Richard C. Wilson, Ryan Armiger, Jason A. Roberts, Alison Holmes, Pantelis Georgiou, Timothy M. Rawson
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Background and objective: Sub-therapeutic dosing of piperacillin-tazobactam in critically-ill patients is associated with poor clinical outcomes and may promote the emergence of drug-resistant infections. In this paper, an in silico investigation of
Externí odkaz:
https://doaj.org/article/c57dc60040a64d91a965876665f27fbb
Autor:
Sarah Denny, Timothy M. Rawson, Peter Hart, Giovanni Satta, Ahmed Abdulaal, Stephen Hughes, Mark Gilchrist, Nabeela Mughal, Luke S. P. Moore
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background We investigated for change in blood stream infections (BSI) with Enterobacterales, coagulase negative staphylococci (CoNS), Streptococcus pneumoniae, and Staphylococcus aureus during the first UK wave of SARS-CoV-2 across five Lon
Externí odkaz:
https://doaj.org/article/43e85737032246e595d5841677ef1b7a
Autor:
Ahmed Al-Hindawi, Ahmed Abdulaal, Timothy M. Rawson, Saleh A. Alqahtani, Nabeela Mughal, Luke S. P. Moore
Publikováno v:
Frontiers in Digital Health, Vol 3 (2021)
The SARS-CoV-2 virus, which causes the COVID-19 pandemic, has had an unprecedented impact on healthcare requiring multidisciplinary innovation and novel thinking to minimize impact and improve outcomes. Wide-ranging disciplines have collaborated incl
Externí odkaz:
https://doaj.org/article/01f46144b9df4476b7137a450e9df8ac